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Cover photograph (Copyright © 2007, American Society for Microbiology. All Rights Reserved.): Subcellular localization of FATP1 in skeletal muscle. Soleus muscle from mice fasted overnight after intraperitoneal injection of insulin is shown. Muscle strips were fixed in 2\% paraformaldehyde, thick sectioned, and stained with antibodies against caveolin 3 (blue), FATP1 (red), and CD36 (green). Nuclei were stained with DAPI (4′,6′-diamidino-2-phenylindole) and are pseudocolored in turquoise. Three-dimensional reconstructions of confocal image stacks and overlay of the different channels were performed using the Volocity program. Caveolin 3 served as a plasma membrane marker illustrating that after insulin stimulation FATP1 is predominantly localized to the sarcolemma. (See related article in May 2006, vol. 26: issue 9, p. 3455.)


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J. Bacteriol. J. Virol. Eukaryot. Cell
Microbiol. Mol. Biol. Rev. Clin. Vaccine Immunol. All ASM Journals

Copyright © 2007 by the American Society for Microbiology. All rights reserved.