Cover photograph (Copyright © 2007, American Society for Microbiology. All Rights Reserved.): The extracellular matrix glycoprotein EMILIN2 triggers cell death upon binding to death receptors. A metaphorical representation of EMILIN2 action based on the famous Caravaggio painting “La Medusa” is shown; the artwork represents an EMILIN2 matrix immunostaining threatening a horrified “blebbing” face. The illustration was designed by Maurizio Mongiat and Stefano Marastoni. (See related article on September 2006, vol. 27: issue 20, p. 7176.)