Table of Contents

Research Article

• Research Article

  The conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth.

  D Poon, S Schroeder, C K Wang, T Yamamoto, M Horikoshi, R G Roeder, P A Weil
• Research Article

  Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.

  C L Farnsworth, L A Feig
• Research Article

  A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.

  J D Hildebrandt, R Day, C L Farnsworth, L A Feig
• Research Article

  Direct-repeat analysis of chromatid interactions during intrachromosomal recombination in mouse cells.

  R J Bollag, R M Liskay
• Research Article

  Characterization of a candidate bcl-1 gene.

  D A Withers, R C Harvey, J B Faust, O Melnyk, K Carey, T C Meeker
• Research Article

  Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products.

  P Cserjesi, E N Olson
• Research Article

  Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP.

  S V Iyer, D L Davis, S N Seal, J B Burch
• Research Article

  Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis.

  H Ronne, M Carlberg, G Z Hu, J O Nehlin
• Research Article

  Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation.

  C L Miller, A L Feldhaus, J W Rooney, L D Rhodes, C H Sibley, H Singh
• Research Article

  Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis.

  O Miura, A D'Andrea, D Kabat, J N Ihle
• Research Article

  v-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine.

  J G Song, L M Pfeffer, D A Foster
• Research Article

  Repression of the Drosophila proliferating-cell nuclear antigen gene promoter by zerknüllt protein.

  M Yamaguchi, F Hirose, Y Nishida, A Matsukage
• Research Article

  Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding.

  W T Pu, K Struhl
• Research Article

  Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.

  K Mizuno, F J Gonzalez, S Kimura
• Research Article

  Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4.

  J C Schneider, L Guarente
• Research Article

  Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts.

  A S Baldwin, J C Azizkhan, D E Jensen, A A Beg, L R Coodly
• Research Article

  Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function.

  A Zentella, F M Weis, D A Ralph, M Laiho, J Massagué
• Research Article

  AGP/EBP(LAP) expressed in rat hepatoma cells interacts with multiple promoter sites and is necessary for maximal glucocorticoid induction of the rat alpha-1 acid glycoprotein gene.

  P Williams, T Ratajczak, S C Lee, G M Ringold
• Research Article

  Light represses transcription of asparagine synthetase genes in photosynthetic and nonphotosynthetic organs of plants.

  F Y Tsai, G Coruzzi
• Research Article

  Chromatin structure, not DNA sequence specificity, is the primary determinant of topoisomerase II sites of action in vivo.

  A Udvardy, P Schedl
• Research Article

  Exocrine pancreas transcription factor 1 binds to a bipartite enhancer element and activates transcription of acinar genes.

  S L Weinrich, A Meister, W J Rutter
• Research Article

  Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70.

  M K Bagchi, S Y Tsai, M J Tsai, B W O'Malley
• Research Article

  Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor.

  M A Lazar, T J Berrodin, H P Harding
• Research Article

  axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

  J P O'Bryan, R A Frye, P C Cogswell, A Neubauer, B Kitch, C Prokop, R Espinosa, M M Le Beau, H S Earp, E T Liu
• Research Article

  Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes.

  E A Musgrove, C S Lee, R L Sutherland
• Research Article

  C/EBP-like proteins binding to the functional box-alpha and box-beta of the second enhancer of hepatitis B virus.

  C H Yuh, L P Ting
• Research Article

  Isolation and characterization of a Chlamydomonas reinhardtii mutant lacking the gamma-subunit of chloroplast coupling factor 1 (CF1).

  E J Smart, B R Selman
• Research Article

  Molecular features of the viral and cellular Src kinases involved in interactions with the GTPase-activating protein.

  B K Brott, S Decker, M C O'Brien, R Jove
• Research Article

  A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.

  M Mohammadi, A M Honegger, D Rotin, R Fischer, F Bellot, W Li, C A Dionne, M Jaye, M Rubinstein, J Schlessinger
• Research Article

  The thyroid hormone receptor gene (c-erbA alpha) is expressed in advance of thyroid gland maturation during the early embryonic development of Xenopus laevis.

  D E Banker, J Bigler, R N Eisenman
• Research Article

  Activation of skeletal alpha-actin gene transcription: the cooperative formation of serum response factor-binding complexes over positive cis-acting promoter serum response elements displaces a negative-acting nuclear factor enriched in replicating myoblasts and nonmyogenic cells.

  T C Lee, K L Chow, P Fang, R J Schwartz
• Research Article

  GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats.

  J S Flick, M Johnston
• Research Article

  Identification and characterization of a novel cytoskeleton-associated pp60src substrate.

  H Wu, A B Reynolds, S B Kanner, R R Vines, J T Parsons
• Research Article

  Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF.

  P Pognonec, R G Roeder
• Research Article

  A hydrophobic protein sequence can override a nuclear localization signal independently of protein context.

  K van Zee, F Appel, E Fanning
• Research Article

  Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene.

  T Decker, D J Lew, J E Darnell
• Research Article

  Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice.

  D D Barker, H Wu, S Hartung, M Breindl, R Jaenisch
• Research Article

  Specificity of a retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter: consequences of both retinoic acid and thyroid hormone receptor binding.

  P C Lucas, B M Forman, H H Samuels, D K Granner
• Research Article

  Convergent transcription initiates from oppositely oriented promoters within the 5' end regions of Drosophila melanogaster F elements.

  G Minchiotti, P P Di Nocera
• Research Article

  Two components of Saccharomyces cerevisiae transcription factor IIIB (TFIIIB) are stereospecifically located upstream of a tRNA gene and interact with the second-largest subunit of TFIIIC.

  B Bartholomew, G A Kassavetis, E P Geiduschek
• Research Article

  c-mos expression in mouse oocytes is controlled by initiator-related sequences immediately downstream of the transcription initiation site.

  S K Pal, S S Zinkel, A A Kiessling, G M Cooper
• Research Article

  Novel protein-DNA interactions associated with increased immunoglobulin transcription in response to antigen plus interleukin-5.

  C F Webb, C Das, S Eaton, K Calame, P W Tucker
• Research Article

  Identification of a matrix-associated region 5' of an immunoglobulin heavy chain variable region gene.

  C F Webb, C Das, K L Eneff, P W Tucker
• Research Article

  In vivo analysis of the Saccharomyces cerevisiae centromere CDEIII sequence: requirements for mitotic chromosome segregation.

  B Jehn, R Niedenthal, J H Hegemann
• Research Article

  Overexpression of transforming growth factor-beta in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene.

  S J Kim, T S Winokur, H D Lee, D Danielpour, K Y Kim, A G Geiser, L S Chen, M B Sporn, A B Roberts, G Jay
• Research Article

  LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes.

  K Lo, N R Landau, S T Smale
• Research Article

  Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events.

  T Triglia, S J Foote, D J Kemp, A F Cowman
• Research Article

  Quantitation of alpha-factor internalization and response during the Saccharomyces cerevisiae cell cycle.

  B Zanolari, H Riezman
• Research Article

  Inhibition of chromatin assembly in Xenopus oocytes correlates with derepression of the mouse mammary tumor virus promoter.

  T Perlmann, O Wrange
• Research Article

  The 40-kilodalton to autoantigen associates with nucleotides 21 to 64 of human mitochondrial RNA processing/7-2 RNA in vitro.

  Y Yuan, E Tan, R Reddy
• Research Article

  Expression of v-src in embryonic neural retina alters cell adhesion, inhibits histogenesis, and prevents induction of glutamine synthetase.

  L Vardimon, L E Fox, R Cohen-Kupiec, L Degenstein, A A Moscona
• Research Article

  RNA polymerase II pauses at the 5' end of the transcriptionally induced Drosophila hsp70 gene.

  T O'Brien, J T Lis
• Research Article

  Splice site choice in a complex transcription unit containing multiple inefficient polyadenylation signals.

  Y Luo, G G Carmichael
• Research Article

  The chromatin structure of Saccharomyces cerevisiae autonomously replicating sequences changes during the cell division cycle.

  J A Brown, S G Holmes, M M Smith
• Research Article

  An RNA-binding protein specifically interacts with a functionally important domain of the downstream element of the simian virus 40 late polyadenylation signal.

  Z W Qian, J Wilusz
• Research Article

  Suppression of the chemically transformed phenotype of BHK cells by a human cDNA.

  M V Eiden, L MacArthur, H Okayama
• Research Article

  Yeast glycolytic mRNAs are differentially regulated.

  P A Moore, F A Sagliocco, R M Wood, A J Brown
• Research Article

  Cloning of a growth arrest-specific and transforming growth factor beta-regulated gene, TI 1, from an epithelial cell line.

  B Kallin, R de Martin, T Etzold, V Sorrentino, L Philipson
• Research Article

  Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins.

  D D Dubey, L R Davis, S A Greenfeder, L Y Ong, J G Zhu, J R Broach, C S Newlon, J A Huberman
• Research Article

  Exon recognition and nucleocytoplasmic partitioning determine AMPD1 alternative transcript production.

  I Mineo, E W Holmes
• Research Article

  The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins.

  J L Brissette, N M Kumar, N B Gilula, G P Dotto
• Research Article

  Heteroduplex formation and mismatch repair of the "stuck" mutation during mating-type switching in Saccharomyces cerevisiae.

  B L Ray, C I White, J E Haber
• Research Article

  Cell-specific regulation of oncogene-responsive sequences of the c-fos promoter.

  A Gutman, C Wasylyk, B Wasylyk