Table of Contents

Research Article

• Research Article

  Identification of base and backbone contacts used for DNA sequence recognition and high-affinity binding by LAC9, a transcription activator containing a C6 zinc finger.

  Y D Halvorsen, K Nandabalan, R C Dickson
• Research Article

  BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

  A J Muller, J C Young, A M Pendergast, M Pondel, N R Landau, D R Littman, O N Witte
• Research Article

  The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation.

  L Naldini, E Vigna, R Ferracini, P Longati, L Gandino, M Prat, P M Comoglio
• Research Article

  Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein.

  M F Moran, P Polakis, F McCormick, T Pawson, C Ellis
• Research Article

  DNase I-hypersensitive sites and transcription factor-binding motifs within the mouse E beta meiotic recombination hot spot.

  R Shenkar, M H Shen, N Arnheim
• Research Article

  Retroviral insertions 90 kilobases proximal to the Evi-1 myeloid transforming gene activate transcription from the normal promoter.

  C Bartholomew, J N Ihle
• Research Article

  Recognition of U1 and U2 small nuclear RNAs can be altered by a 5-amino-acid segment in the U2 small nuclear ribonucleoprotein particle (snRNP) B" protein and through interactions with U2 snRNP-A' protein.

  R C Bentley, J D Keene
• Research Article

  Biosynthesis of human fibroblast growth factor-5.

  B Bates, J Hardin, X Zhan, K Drickamer, M Goldfarb
• Research Article

  Ecdysterone regulatory elements function as both transcriptional activators and repressors.

  L Dobens, K Rudolph, E M Berger
• Research Article

  Characterization of the BCR promoter in Philadelphia chromosome-positive and -negative cell lines.

  N P Shah, O N Witte, C T Denny
• Research Article

  Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction.

  R H Chen, J Chung, J Blenis
• Research Article

  Coordinate regulation of pp90rsk and a distinct protein-serine/threonine kinase activity that phosphorylates recombinant pp90rsk in vitro.

  J Chung, R H Chen, J Blenis
• Research Article

  Identification and characterization of a novel enhancer for the rat neu promoter.

  D H Yan, M C Hung
• Research Article

  An in vitro transcription analysis of early responses of the human immunodeficiency virus type 1 long terminal repeat to different transcriptional activators.

  Y C Li, J Ross, J A Scheppler, B R Franza
• Research Article

  Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster.

  C Holdridge, D Dorsett
• Research Article

  A muscle-specific intron enhancer required for rescue of indirect flight muscle and jump muscle function regulates Drosophila tropomyosin I gene expression.

  J R Schultz, T Tansey, L Gremke, R V Storti
• Research Article

  Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential.

  S Katzav, J L Cleveland, H E Heslop, D Pulido
• Research Article

  Insertion of part of an intron into the 5' untranslated region of a Caenorhabditis elegans gene converts it into a trans-spliced gene.

  R Conrad, J Thomas, J Spieth, T Blumenthal
• Research Article

  Cell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cells.

  W G McGregor, R H Chen, L Lukash, V M Maher, J J McCormick
• Research Article

  Synergistic activation of a human promoter in vivo by transcription factor Sp1.

  G M Anderson, S O Freytag
• Research Article

  Identification of single-stranded-DNA-binding proteins that interact with muscle gene elements.

  I M Santoro, T M Yi, K Walsh
• Research Article

  Synergistic interactions of silkmoth chorion promoter-binding factors.

  Y A Skeiky, K Iatrou
• Research Article

  Cell cycle tyrosine phosphorylation of p34cdc2 and a microtubule-associated protein kinase homolog in Xenopus oocytes and eggs.

  J E Ferrell, M Wu, J C Gerhart, G S Martin
• Research Article

  Requirement of phosphatidylinositol-3 kinase modification for its association with p60src.

  Y Fukui, H Hanafusa
• Research Article

  The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains.

  A D D'Andrea, A Yoshimura, H Youssoufian, L I Zon, J W Koo, H F Lodish
• Research Article

  Control of protein phosphatase 2A by simian virus 40 small-t antigen.

  S I Yang, R L Lickteig, R Estes, K Rundell, G Walter, M C Mumby
• Research Article

  Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigen.

  K H Scheidtmann, M C Mumby, K Rundell, G Walter
• Research Article

  Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation.

  L E Hyman, S H Seiler, J Whoriskey, C L Moore
• Research Article

  Effects of controlled RAD52 expression on repair and recombination in Saccharomyces cerevisiae.

  K J Dornfeld, D M Livingston
• Research Article

  Platelet-derived growth factor increases the in vivo activity of phospholipase C-gamma 1 and phospholipase C-gamma 2.

  L Sultzman, C Ellis, L L Lin, T Pawson, J Knopf
• Research Article

  A new U6 small nuclear ribonucleoprotein-specific protein conserved between cis- and trans-splicing systems.

  K Gröning, Z Palfi, S Gupta, M Cross, T Wolff, A Bindereif
• Research Article

  Accurate transcription of a plant mitochondrial gene in vitro.

  P J Hanic-Joyce, M W Gray
• Research Article

  The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency.

  F Fazioli, U H Kim, S G Rhee, C J Molloy, O Segatto, P P Di Fiore
• Research Article

  Activation of the silent endogenous cholesterol-7-alpha-hydroxylase gene in rat hepatoma cells: a new complementation group having resistance to 25-hydroxycholesterol.

  J K Leighton, S Dueland, M S Straka, J Trawick, R A Davis
• Research Article

  Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

  A F Wilks, A G Harpur, R R Kurban, S J Ralph, G Zürcher, A Ziemiecki
• Research Article

  An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice.

  J L Slack, D J Liska, P Bornstein
• Research Article

  Cross-resistance to UV radiation of a cisplatin-resistant human cell line: overexpression of cellular factors that recognize UV-modified DNA.

  C C Chao, S L Huang, H M Huang, S Lin-Chao
• Research Article

  Human DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cells.

  B E Pearson, H P Nasheuer, T S Wang
• Research Article

  Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation.

  A Alessandrini, S V Desiderio
• Research Article

  Effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase alpha-primase.

  K L Collins, T J Kelly
• Research Article

  Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products.

  P Yaciuk, M C Carter, J M Pipas, E Moran
• Research Article

  Organization and chromosomal localization of the human platelet-derived endothelial cell growth factor gene.

  K Hagiwara, G Stenman, H Honda, P Sahlin, A Andersson, K Miyazono, C H Heldin, F Ishikawa, F Takaku
• Research Article

  The SIT4 protein phosphatase functions in late G1 for progression into S phase.

  A Sutton, D Immanuel, K T Arndt
• Research Article

  Translation initiation in Drosophila melanogaster is reduced by mutations upstream of the AUG initiator codon.

  Y Feng, L E Gunter, E L Organ, D R Cavener
• Research Article

  Cloning and characterization of a human c-myc promoter-binding protein.

  R Ray, D M Miller
• Research Article

  In vitro studies of the binding of the ARGR proteins to the ARG5,6 promoter.

  E Dubois, F Messenguy
• Research Article

  Dissection of the bifunctional ARGRII protein involved in the regulation of arginine anabolic and catabolic pathways.

  H F Qui, E Dubois, F Messenguy
• Research Article

  A family of genes related to a new expression site-associated gene in Trypanosoma equiperdum.

  I C Florent, A Raibaud, H Eisen
• Research Article

  Developmental expression of Sp1 in the mouse.

  J D Saffer, S P Jackson, M B Annarella
• Research Article

  Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).

  J K Batra, D J Fitzgerald, V K Chaudhary, I Pastan
• Research Article

  Identification of DNA regions required for mitotic and meiotic functions within the centromere of Schizosaccharomyces pombe chromosome I.

  K M Hahnenberger, J Carbon, L Clarke
• Research Article

  The functional domains of the murine Thy-1 gene promoter.

  E Spanopoulou, V Giguere, F Grosveld
• Research Article

  Transcripts from amplified sequences of an inherited homogeneously staining region in chromosome 1 of the house mouse (Mus musculus).

  W A Eckert, C Plass, A Weith, W Traut, H Winking
• Research Article

  In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria.

  A Chomyn, G Meola, N Bresolin, S T Lai, G Scarlato, G Attardi
• Research Article

  Differential introduction of DNA damage and repair in mammalian genes transcribed by RNA polymerases I and II.

  J M Vos, E L Wauthier
• Research Article

  The SIR1 gene of Saccharomyces cerevisiae and its role as an extragenic suppressor of several mating-defective mutants.

  E M Stone, M J Swanson, A M Romeo, J B Hicks, R Sternglanz
• Research Article

  Autonomous DNA replication in human cells is affected by the size and the source of the DNA.

  S S Heinzel, P J Krysan, C T Tran, M P Calos
• Research Article

  A conserved 28-base-pair element (HF-1) in the rat cardiac myosin light-chain-2 gene confers cardiac-specific and alpha-adrenergic-inducible expression in cultured neonatal rat myocardial cells.

  H Zhu, A V Garcia, R S Ross, S M Evans, K R Chien
• Research Article

  Characterization of a telomere-binding protein from Physarum polycephalum.

  J S Coren, E M Epstein, V M Vogt
• Research Article

  Transcriptional suppression of cellular gene expression by c-Myc.

  B S Yang, T J Geddes, R J Pogulis, B de Crombrugghe, S O Freytag
• Research Article

  Identification of a 70-base-pair cell cycle regulatory unit within the promoter of the human thymidine kinase gene and its interaction with cellular factors.

  Y K Kim, A S Lee
• Research Article

  The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes.

  H S Ro, D A Roncari
• Research Article

  Lovastatin selectively inhibits ras activation of the 12-O-tetradecanoylphorbol-13-acetate response element in mammalian cells.

  D Defeo-Jones, E M McAvoy, R E Jones, G A Vuocolo, K M Haskell, R J Wegrzyn, A Oliff
• Research Article

  GAL11 (SPT13), a transcriptional regulator of diverse yeast genes, affects the phosphorylation state of GAL4, a highly specific transcriptional activator.

  R M Long, L M Mylin, J E Hopper
• Research Article

  Cyclic AMP-independent activation of transcription factor NF-kappa B in HL60 cells by tumor necrosis factors alpha and beta.

  H P Hohmann, R Kolbeck, R Remy, A P van Loon
• Research Article

  Identification of a fibroblast growth factor-binding protein in Drosophila melanogaster.

  J S Doctor, F M Hoffmann, B B Olwin
• Research Article

  The developmentally regulated shift from membrane to secreted mu mRNA production is accompanied by an increase in cleavage-polyadenylation efficiency but no measurable change in splicing efficiency.

  M L Peterson, E R Gimmi, R P Perry
• Research Article

  Introduction of exogenous DNA into Chlamydomonas reinhardtii by electroporation.

  L E Brown, S L Sprecher, L R Keller