Table of Contents

Research Article

• Research Article

  Alternatively spliced murine lyn mRNAs encode distinct proteins.

  E Stanley, S Ralph, S McEwen, I Boulet, D A Holtzman, P Lock, A R Dunn
• Research Article

  A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs.

  J C Vera, G R Castillo, O M Rosen
• Research Article

  The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities.

  C G Burd, E L Matunis, G Dreyfuss
• Research Article

  Detection and characterization of a factor which rescues spliceosome assembly from a heat-inactivated HeLa cell nuclear extract.

  P Delannoy, M H Caruthers
• Research Article

  Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function.

  D A Wassarman, J A Steitz
• Research Article

  Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatment.

  X A Li, A S Lee
• Research Article

  Differential regional expression of three natriuretic peptide receptor genes within primate tissues.

  J N Wilcox, A Augustine, D V Goeddel, D G Lowe
• Research Article

  Translation initiation factor 4A from Saccharomyces cerevisiae: analysis of residues conserved in the D-E-A-D family of RNA helicases.

  S R Schmid, P Linder
• Research Article

  Excess wild-type p53 blocks initiation and maintenance of simian virus 40 transformation.

  K Fukasawa, G Sakoulas, R E Pollack, S Chen
• Research Article

  An endoplasmic reticulum-specific cyclophilin.

  K W Hasel, J R Glass, M Godbout, J G Sutcliffe
• Research Article

  Pituitary pro-opiomelanocortin gene expression requires synergistic interactions of several regulatory elements.

  M Therrien, J Drouin
• Research Article

  Modular recognition of 5-base-pair DNA sequence motifs by human heat shock transcription factor.

  N F Cunniff, J Wagner, W D Morgan
• Research Article

  The block to transcription elongation at the minute virus of mice attenuator is regulated by cellular elongation factors.

  A Krauskopf, E Bengal, Y Aloni
• Research Article

  Poly(ADP-ribose) polymerase inhibitors suppress UV-induced human immunodeficiency virus type 1 gene expression at the posttranscriptional level.

  S Yamagoe, T Kohda, M Oishi
• Research Article

  Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line.

  N L Lumelsky, B G Forget
• Research Article

  Mutational analysis of CDC42Sc, a Saccharomyces cerevisiae gene that encodes a putative GTP-binding protein involved in the control of cell polarity.

  M Ziman, J M O'Brien, L A Ouellette, W R Church, D I Johnson
• Research Article

  In vivo characterization of the Saccharomyces cerevisiae centromere DNA element I, a binding site for the helix-loop-helix protein CPF1.

  R Niedenthal, R Stoll, J H Hegemann
• Research Article

  byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype.

  Y Wang, H P Xu, M Riggs, L Rodgers, M Wigler
• Research Article

  Identification of cis sequences controlling efficient position-independent tissue-specific expression of human major histocompatibility complex class I genes in transgenic mice.

  J W Chamberlain, H A Vasavada, S Ganguly, S M Weissman
• Research Article

  Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells.

  R Buettner, S O Yim, Y S Hong, E Boncinelli, M A Tainsky
• Research Article

  The complex set of late transcripts from the Drosophila sex determination gene sex-lethal encodes multiple related polypeptides.

  M E Samuels, P Schedl, T W Cline
• Research Article

  Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone.

  S Marcus, G A Caldwell, D Miller, C B Xue, F Naider, J M Becker
• Research Article

  DNA-binding specificity of the fushi tarazu homeodomain.

  B Florence, R Handrow, A Laughon
• Research Article

  Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains.

  C Abate, D Luk, T Curran
• Research Article

  Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding.

  T Chakraborty, T J Brennan, L Li, D Edmondson, E N Olson
• Research Article

  RAP1 is required for BAS1/BAS2- and GCN4-dependent transcription of the yeast HIS4 gene.

  C Devlin, K Tice-Baldwin, D Shore, K T Arndt
• Research Article

  Mutation of serum response factor phosphorylation sites and the mechanism by which its DNA-binding activity is increased by casein kinase II.

  J R Manak, R Prywes
• Research Article

  Ecdysterone receptor is a sequence-specific transcription factor involved in the developmental regulation of heat shock genes.

  Y Luo, J Amin, R Voellmy
• Research Article

  Role of heat shock transcription factor in yeast metallothionein gene expression.

  W M Yang, W Gahl, D Hamer
• Research Article

  The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts.

  D Jähner, T Hunter
• Research Article

  Protein synthesis requirements for nuclear division, cytokinesis, and cell separation in Saccharomyces cerevisiae.

  D J Burke, D Church
• Research Article

  Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells.

  M D Sklar, E Thompson, M J Welsh, M Liebert, J Harney, H B Grossman, M Smith, E V Prochownik
• Research Article

  Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes.

  W K Kaufmann, J C Boyer, L L Estabrooks, S J Wilson
• Research Article

  Regulation of a double-stranded RNA modification activity in human cells.

  L M Morrissey, K Kirkegaard
• Research Article

  Changes in dihydrofolate reductase (DHFR) mRNA levels can account fully for changes in DHFR synthesis rates during terminal differentiation in a highly amplified myogenic cell line.

  E E Schmidt, G F Merrill
• Research Article

  The myosin light chain enhancer and the skeletal actin promoter share a binding site for factors involved in muscle-specific gene expression.

  H Ernst, K Walsh, C A Harrison, N Rosenthal
• Research Article

  Beta-casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammary-gland-specific nuclear factor.

  M Schmitt-Ney, W Doppler, R K Ball, B Groner
• Research Article

  Platelet-derived growth factor (PDGF)-induced disulfide-linked dimerization of PDGF receptor in living cells.

  W Li, J Schlessinger
• Research Article

  Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1(HAP1) activator binds to the CYB2 upstream activation site UAS1-B2.

  T Lodi, B Guiard
• Research Article

  AAR1/TUP1 protein, with a structure similar to that of the beta subunit of G proteins, is required for a1-alpha 2 and alpha 2 repression in cell type control of Saccharomyces cerevisiae.

  Y Mukai, S Harashima, Y Oshima
• Research Article

  Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction.

  J C Yu, M A Heidaran, J H Pierce, J S Gutkind, D Lombardi, M Ruggiero, S A Aaronson
• Research Article

  Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice.

  M Albitar, M Katsumata, S A Liebhaber
• Research Article

  Secretion and transcriptional regulation of transforming growth factor-beta 3 during myogenesis.

  R Lafyatis, R Lechleider, A B Roberts, M B Sporn
• Research Article

  The HXT1 gene product of Saccharomyces cerevisiae is a new member of the family of hexose transporters.

  D A Lewis, L F Bisson
• Research Article

  A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways.

  J N Rottman, R L Widom, B Nadal-Ginard, V Mahdavi, S K Karathanasis