Table of Contents

Research Article

• Research Article

  trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor.

  L C Webster, R P Ricciardi
• Research Article

  E1A-mediated activation of the adenovirus E4 promoter can occur independently of the cellular transcription factor E4F.

  C Jones, K A Lee
• Research Article

  Inhibition of translation of transforming growth factor-beta 3 mRNA by its 5' untranslated region.

  B A Arrick, A L Lee, R L Grendell, R Derynck
• Research Article

  Liver cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response elements 1 and 2 (XRE1 and -2) of the rat cytochrome P-450IA1 gene and a constitutive, nuclear XRE-binding factor that is distinct from the dioxin receptor.

  J Hapgood, S Cuthill, P Söderkvist, A Wilhelmsson, I Pongratz, R H Tukey, E F Johnson, J A Gustafsson, L Poellinger
• Research Article

  Derepression of mouse beta-major-globin gene transcription during erythroid differentiation.

  K Macleod, M Plumb
• Research Article

  Determination of Candida tropicalis acyl coenzyme A oxidase isozyme function by sequential gene disruption.

  S Picataggio, K Deanda, J Mielenz
• Research Article

  Expression of the murine alpha B-crystallin gene in lens and skeletal muscle: identification of a muscle-preferred enhancer.

  R A Dubin, R Gopal-Srivastava, E F Wawrousek, J Piatigorsky
• Research Article

  In situ distinction between steroid receptor binding and transactivation at a target gene.

  D P McDonnell, Z Nawaz, B W O'Malley
• Research Article

  Mutational analysis of the DNA-binding domain of the CYS3 regulatory protein of Neurospora crassa.

  M N Kanaan, G A Marzluf
• Research Article

  Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization.

  P Lock, S Ralph, E Stanley, I Boulet, R Ramsay, A R Dunn
• Research Article

  Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation.

  K A Lord, A Abdollahi, S M Thomas, M DeMarco, J S Brugge, B Hoffman-Liebermann, D A Liebermann
• Research Article

  Specific binding of chloroplast proteins in vitro to the 3' untranslated region of spinach chloroplast petD mRNA.

  H C Chen, D B Stern
• Research Article

  Double-strand gap repair in a mammalian gene targeting reaction.

  V Valancius, O Smithies
• Research Article

  High expression of a 3'----5' exonuclease activity is specific to B lymphocytes.

  A L Kenter, J Tredup
• Research Article

  The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology.

  C M DiPersio, D A Jackson, K S Zaret
• Research Article

  CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli.

  C T Weaver, J T Pingel, J O Nelson, M L Thomas
• Research Article

  Transactivation of pancreas-specific gene sequences in somatic cell hybrids.

  K J Wu, L C Samuelson, G Howard, M H Meisler, G J Darlington
• Research Article

  Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes.

  J A Augustine, S L Sutor, R T Abraham
• Research Article

  Repair of a synthetic abasic site involves concerted reactions of DNA synthesis followed by excision and ligation.

  Y Matsumoto, D F Bogenhagen
• Research Article

  Differential regulation of glucose transporter isoforms by the src oncogene in chicken embryo fibroblasts.

  M K White, T B Rall, M J Weber
• Research Article

  Physiological and genetic analysis of the carbon regulation of the NAD-dependent glutamate dehydrogenase of Saccharomyces cerevisiae.

  P W Coschigano, S M Miller, B Magasanik
• Research Article

  The jun and fos protein families are both required for cell cycle progression in fibroblasts.

  K Kovary, R Bravo
• Research Article

  Phorbol esters selectively and reversibly inhibit a subset of myofibrillar genes responsible for the ongoing differentiation program of chick skeletal myotubes.

  J K Choi, S Holtzer, S A Chacko, Z X Lin, R K Hoffman, H Holtzer
• Research Article

  Assessment of the transcriptional activation potential of the HMG chromosomal proteins.

  D Landsman, M Bustin
• Research Article

  Glucocorticoid regulation of transforming growth factor beta 1 activity and binding in osteoblast-enriched cultures from fetal rat bone.

  M Centrella, T L McCarthy, E Canalis
• Research Article

  Synapsis, strand scission, and strand exchange induced by the FLP recombinase: analysis with half-FRT sites.

  A Amin, H Roca, K Luetke, P D Sadowski
• Research Article

  Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells.

  P Hasty, J Rivera-Pérez, C Chang, A Bradley
• Research Article

  Restriction of neuroblastoma to the prostate gland in transgenic mice.

  D G Skalnik, D M Dorfman, D A Williams, S H Orkin
• Research Article

  HMG1-related DNA-binding protein isolated with V-(D)-J recombination signal probes.

  M Shirakata, K Hüppi, S Usuda, K Okazaki, K Yoshida, H Sakano
• Research Article

  Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation.

  D Ramotar, S C Popoff, E B Gralla, B Demple
• Research Article

  The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts.

  R P Misra, V M Rivera, J M Wang, P D Fan, M E Greenberg
• Research Article

  Transcriptional activation in an improved whole-cell extract from Saccharomyces cerevisiae.

  M Woontner, P A Wade, J Bonner, J A Jaehning
• Research Article

  Differential ability of proximal and remote element pairs to cooperate in activating RNA polymerase II transcription.

  W D Wang, J D Gralla
• Research Article

  Telomerase is processive.

  C W Greider
• Research Article

  Identification of a specific exon sequence that is a major determinant in the selection between a natural and a cryptic 5' splice site.

  L Domenjoud, H Gallinaro, L Kister, S Meyer, M Jacob
• Research Article

  Interactions between adenylate cyclase and the yeast GTPase-activating protein IRA1.

  M R Mitts, J Bradshaw-Rouse, W Heideman
• Research Article

  Analysis of premature termination in c-myc during transcription by RNA polymerase II in a HeLa nuclear extract.

  L London, R G Keene, R Landick
• Research Article

  Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1.

  L Brizuela, G Chrebet, K A Bostian, S A Parent
• Research Article

  The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain.

  D E Johnson, J Lu, H Chen, S Werner, L T Williams
• Research Article

  trans activation of nerve growth factor in transgenic mice containing the human T-cell lymphotropic virus type I tax gene.

  J E Green
• Research Article

  The gene encoding the transcription factor SCIP has features of an expressed retroposon.

  R Kuhn, E S Monuki, G Lemke
• Research Article

  elt-1, an embryonically expressed Caenorhabditis elegans gene homologous to the GATA transcription factor family.

  J Spieth, Y H Shim, K Lea, R Conrad, T Blumenthal
• Research Article

  Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments.

  G Fritz, K Tano, S Mitra, B Kaina
• Research Article

  Mutations in the three largest subunits of yeast RNA polymerase II that affect enzyme assembly.

  P A Kolodziej, R A Young
• Research Article

  Characterization of the major regulatory element upstream of the human alpha-globin gene cluster.

  A P Jarman, W G Wood, J A Sharpe, G Gourdon, H Ayyub, D R Higgs
• Research Article

  5'-flanking sequences mediate butyrate stimulation of embryonic globin gene expression in adult erythroid cells.

  J G Glauber, N J Wandersee, J A Little, G D Ginder
• Research Article

  Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce early response gene transcription.

  P van der Geer, T Hunter
• Research Article

  Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.

  M Kelliher, A Knott, J McLaughlin, O N Witte, N Rosenberg
• Research Article

  Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

  Y S Cheng, C E Patterson, P Staeheli
• Research Article

  A codon change in beta-tubulin which drastically affects microtubule structure in Drosophila melanogaster fails to produce a significant phenotype in Saccharomyces cerevisiae.

  V Praitis, W S Katz, F Solomon
• Research Article

  Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and posttranscriptional levels in response to lipopolysaccharide.

  K Brand, B J Fowler, T S Edgington, N Mackman
• Research Article

  Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation.

  S M Thomas, M Hayes, G D'Arcangelo, R C Armstrong, B E Meyer, A Zilberstein, J S Brugge, S Halegoua
• Research Article

  Tec2, a second transposon-like element demonstrating developmentally programmed excision in Euplotes crassus.

  M F Krikau, C L Jahn
• Research Article

  The amino-terminal 14 amino acids of v-src can functionally replace the extracellular and transmembrane domains of v-erbB.

  M McMahon, R C Schatzman, J M Bishop
• Research Article

  Retinoic acid-induced down-regulation of the interleukin-2 promoter via cis-regulatory sequences containing an octamer motif.

  M P Felli, A Vacca, D Meco, I Screpanti, A R Farina, M Maroder, S Martinotti, E Petrangeli, L Frati, A Gulino
• Research Article

  Replication timing control can be maintained in extrachromosomally amplified genes.

  S M Carroll, J Trotter, G M Wahl
• Research Article

  Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.

  J S Gibbs, K Weisshart, P Digard, A deBruynKops, D M Knipe, D M Coen
• Research Article

  Multiple CArG boxes in the human cardiac actin gene promoter required for expression in embryonic cardiac muscle cells developing in vitro from embryonal carcinoma cells.

  G Pari, K Jardine, M W McBurney
• Research Article

  Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cells.

  S L Martin