Table of Contents

Research Article

• Research Article

  The retinoblastoma gene product regulates Sp1-mediated transcription.

  S J Kim, U S Onwuta, Y I Lee, R Li, M R Botchan, P D Robbins
• Research Article

  The role and fate of DNA ends for homologous recombination in embryonic stem cells.

  P Hasty, J Rivera-Pérez, A Bradley
• Research Article

  Point mutations in the Drosophila hairy gene demonstrate in vivo requirements for basic, helix-loop-helix, and WRPW domains.

  S M Wainwright, D Ish-Horowicz
• Research Article

  Expression of MRF4, a myogenic helix-loop-helix protein, produces multiple changes in the myogenic program of BC3H-1 cells.

  N E Block, J B Miller
• Research Article

  Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis.

  M Selvakumaran, D A Liebermann, B Hoffman-Liebermann
• Research Article

  Nerve growth factor-induced derepression of peripherin gene expression is associated with alterations in proteins binding to a negative regulatory element.

  M A Thompson, E Lee, D Lawe, E Gizang-Ginsberg, E B Ziff
• Research Article

  Specific transcription factors stimulate simian virus 40 and polyomavirus origins of DNA replication.

  Z S Guo, M L DePamphilis
• Research Article

  Negative regulation of catalase gene expression in hepatoma cells.

  K Sato, K Ito, H Kohara, Y Yamaguchi, K Adachi, H Endo
• Research Article

  GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.

  A Kazlauskas, A Kashishian, J A Cooper, M Valius
• Research Article

  High-frequency germ line gene conversion in transgenic mice.

  J R Murti, M Bumbulis, J C Schimenti
• Research Article

  Growth-dependent inhibition of CCAAT enhancer-binding protein (C/EBP alpha) gene expression during hepatocyte proliferation in the regenerating liver and in culture.

  D Mischoulon, B Rana, N L Bucher, S R Farmer
• Research Article

  Saccharomyces cerevisiae contains an RNase MRP that cleaves at a conserved mitochondrial RNA sequence implicated in replication priming.

  L L Stohl, D A Clayton
• Research Article

  The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor alpha.

  E White, P Sabbatini, M Debbas, W S Wold, D I Kusher, L R Gooding
• Research Article

  Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases.

  K J Koller, F J de Sauvage, D G Lowe, D V Goeddel
• Research Article

  Specific cleavage of pre-edited mRNAs in trypanosome mitochondrial extracts.

  M Harris, C Decker, B Sollner-Webb, S Hajduk
• Research Article

  The hsp70 gene CCAAT-binding factor mediates transcriptional activation by the adenovirus E1a protein.

  L S Lum, S Hsu, M Vaewhongs, B Wu
• Research Article

  Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein.

  A D Cox, M M Hisaka, J E Buss, C J Der
• Research Article

  HAP1 and ROX1 form a regulatory pathway in the repression of HEM13 transcription in Saccharomyces cerevisiae.

  T Keng
• Research Article

  Posttranscriptional regulation of rat growth hormone gene expression: increased message stability and nuclear polyadenylation accompany thyroid hormone depletion.

  D Murphy, K Pardy, V Seah, D Carter
• Research Article

  STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs.

  S S Wang, D R Stanford, C D Silvers, A K Hopper
• Research Article

  The promoter for the procyclic acidic repetitive protein (PARP) genes of Trypanosoma brucei shares features with RNA polymerase I promoters.

  S D Brown, J Huang, L H Van der Ploeg
• Research Article

  Anti-Cdc25 antibodies inhibit guanyl nucleotide-dependent adenylyl cyclase of Saccharomyces cerevisiae and cross-react with a 150-kilodalton mammalian protein.

  E Gross, I Marbach, D Engelberg, M Segal, G Simchen, A Levitzki
• Research Article

  The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP.

  Z Kozmik, S Wang, P Dörfler, B Adams, M Busslinger
• Research Article

  SRN1, a yeast gene involved in RNA processing, is identical to HEX2/REG1, a negative regulator in glucose repression.

  K S Tung, L L Norbeck, S L Nolan, N S Atkinson, A K Hopper
• Research Article

  Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.

  E M Douville, D E Afar, B W Howell, K Letwin, L Tannock, Y Ben-David, T Pawson, J C Bell
• Research Article

  Characterization of the DNA-binding activity of GCR1: in vivo evidence for two GCR1-binding sites in the upstream activating sequence of TPI of Saccharomyces cerevisiae.

  M A Huie, E W Scott, C M Drazinic, M C Lopez, I K Hornstra, T P Yang, H V Baker
• Research Article

  Overproduction of the GAL1 or GAL3 protein causes galactose-independent activation of the GAL4 protein: evidence for a new model of induction for the yeast GAL/MEL regulon.

  P J Bhat, J E Hopper
• Research Article

  Interaction of basal positive and negative transcription elements controls repression of the proximal rat prolactin promoter in nonpituitary cells.

  S M Jackson, C A Keech, D J Williamson, A Gutierrez-Hartmann
• Research Article

  Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck.

  L Caron, N Abraham, T Pawson, A Veillette
• Research Article

  X rays induce interallelic homologous recombination at the human thymidine kinase gene.

  M B Benjamin, J B Little
• Research Article

  Negative autoregulation of the neu gene is mediated by a novel enhancer.

  X Y Zhao, M C Hung
• Research Article

  Instability of simple sequence DNA in Saccharomyces cerevisiae.

  S T Henderson, T D Petes
• Research Article

  Functional dissection of the lck proximal promoter.

  J M Allen, K A Forbush, R M Perlmutter
• Research Article

  Investigation of coelectroporation as a method for introducing small mutations into embryonic stem cells.

  A C Davis, M Wims, A Bradley
• Research Article

  Isolation of telomerelike sequences from Cryptococcus neoformans and their use in high-efficiency transformation.

  J C Edman
• Research Article

  Mutations in the zinc fingers of ADR1 that change the specificity of DNA binding and transactivation.

  S K Thukral, M L Morrison, E T Young
• Research Article

  Identification of a novel enhancer element mediating calcium-dependent induction of gene expression in response to either epidermal growth factor or activation of protein kinase C.

  P Lenormand, D Pribnow, K D Rodland, B E Magun
• Research Article

  Activation of a mammalian origin of replication by chromosomal rearrangement.

  T H Leu, J L Hamlin
• Research Article

  Posttranslational control of Ty1 retrotransposition occurs at the level of protein processing.

  M J Curcio, D J Garfinkel
• Research Article

  DNA-binding properties of the E1A-associated 300-kilodalton protein.

  Y Rikitake, E Moran
• Research Article

  E1A-responsive elements for repression of rat fibronectin gene transcription.

  T Nakajima, T Nakamura, S Tsunoda, S Nakada, K Oda
• Research Article

  Role of the liver-enriched transcription factor DBP in expression of the cytochrome P450 CYP2C6 gene.

  M Yano, E Falvey, F J Gonzalez
• Research Article

  Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene.

  D M Henderson, C D Sifri, M Rodgers, D F Wirth, N Hendrickson, B Ullman
• Research Article

  A transcriptionally active DNA-binding site for human p53 protein complexes.

  W D Funk, D T Pak, R H Karas, W E Wright, J W Shay
• Research Article

  Global regulation of mitochondrial biogenesis in Saccharomyces cerevisiae: ABF1 and CPF1 play opposite roles in regulating expression of the QCR8 gene, which encodes subunit VIII of the mitochondrial ubiquinol-cytochrome c oxidoreductase.

  J H de Winde, L A Grivell
• Research Article

  Anatomy of an unusual RNA polymerase II promoter containing a downstream TATA element.

  Y Kasai, H Chen, S J Flint
• Research Article

  Rapid induction in regenerating liver of RL/IF-1 (an I kappa B that inhibits NF-kappa B, RelB-p50, and c-Rel-p50) and PHF, a novel kappa B site-binding complex.

  M Tewari, P Dobrzanski, K L Mohn, D E Cressman, J C Hsu, R Bravo, R Taub