Table of Contents

Research Article

• Research Article

  Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating.

  K L Clark, D Dignard, D Y Thomas, M Whiteway
• Research Article

  An opportunistic promoter sharing regulatory sequences with either a muscle-specific or a ubiquitous promoter in the human aldolase A gene.

  J P Concordet, M Salminen, J Demignon, C Moch, P Maire, A Kahn, D Daegelen
• Research Article

  Sperm-specific expression of angiotensin-converting enzyme (ACE) is mediated by a 91-base-pair promoter containing a CRE-like element.

  T Howard, R Balogh, P Overbeek, K E Bernstein
• Research Article

  Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae.

  P W Sherwood, S V Tsang, M A Osley
• Research Article

  The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras Asn-17.

  F Schweighoffer, H Cai, M C Chevallier-Multon, I Fath, G Cooper, B Tocque
• Research Article

  Discrimination among potential activators of the beta-globin CACCC element by correlation of binding and transcriptional properties.

  G A Hartzog, R M Myers
• Research Article

  MCM1 binds to a transcriptional control element in Ty1.

  B Errede
• Research Article

  SPT13 (GAL11) of Saccharomyces cerevisiae negatively regulates activity of the MCM1 transcription factor in Ty1 elements.

  G Yu, J S Fassler
• Research Article

  Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility.

  K Takaishi, A Kikuchi, S Kuroda, K Kotani, T Sasaki, Y Takai
• Research Article

  Schizosaccharomyces pombe map3+ encodes the putative M-factor receptor.

  K Tanaka, J Davey, Y Imai, M Yamamoto
• Research Article

  Identification of a negative element in the human vimentin promoter: modulation by the human T-cell leukemia virus type I Tax protein.

  A Salvetti, A Lilienbaum, Z Li, D Paulin, L Gazzolo
• Research Article

  Transcriptional inhibition of the murine erythropoietin receptor gene by an upstream repetitive element.

  H Youssoufian, H F Lodish
• Research Article

  A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation.

  J N Feder, L Y Jan, Y N Jan
• Research Article

  Gene RRN4 in Saccharomyces cerevisiae encodes the A12.2 subunit of RNA polymerase I and is essential only at high temperatures.

  Y Nogi, R Yano, J Dodd, C Carles, M Nomura
• Research Article

  Identification of amino acids essential for DNA binding and dimerization in p67SRF: implications for a novel DNA-binding motif.

  A D Sharrocks, H Gille, P E Shaw
• Research Article

  Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.

  M Valius, C Bazenet, A Kazlauskas
• Research Article

  RNA B is the major nucleolar trimethylguanosine-capped small nuclear RNA associated with fibrillarin and pre-rRNAs in Trypanosoma brucei.

  T Hartshorne, N Agabian
• Research Article

  Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras.

  R H Medema, A M de Vries-Smits, G C van der Zon, J A Maassen, J L Bos
• Research Article

  An abundant high-mobility-group-like protein is targeted to micronuclei in a cell cycle-dependent and developmentally regulated fashion in Tetrahymena thermophila.

  T Wang, C D Allis
• Research Article

  Isolation of RRM-type RNA-binding protein genes and the analysis of their relatedness by using a numerical approach.

  Y J Kim, B S Baker
• Research Article

  A transcriptional switch between the Pig-1 and Sgs-4 genes of Drosophila melanogaster.

  E Mougneau, D von Seggern, T Fowler, J Rosenblatt, T Jongens, B Rogers, D Gietzen, S K Beckendorf
• Research Article

  Two domains of ISGF3 gamma that mediate protein-DNA and protein-protein interactions during transcription factor assembly contribute to DNA-binding specificity.

  S A Veals, T Santa Maria, D E Levy
• Research Article

  Genomic and transcriptional linkage of the genes for calmodulin, EF-hand 5 protein, and ubiquitin extension protein 52 in Trypanosoma brucei.

  S Wong, T H Morales, J E Neigel, D A Campbell
• Research Article

  A Drosophila homolog of bovine smg p25a GDP dissociation inhibitor undergoes a shift in isoelectric point in the developmental mutant quartet.

  J E Zahner, C M Cheney
• Research Article

  Molecular basis for developmental changes in interleukin-2 gene inducibility.

  D Chen, E V Rothenberg
• Research Article

  Localization of small heat shock proteins to the higher plant endomembrane system.

  K W Helm, P R LaFayette, R T Nagao, J L Key, E Vierling
• Research Article

  Identification of cis and trans components of a novel heat shock stress regulatory pathway in Saccharomyces cerevisiae.

  N Kobayashi, K McEntee
• Research Article

  Identification of a retinoic acid response element upstream of the murine Hox-4.2 gene.

  H Pöpperl, M S Featherstone
• Research Article

  Transcriptional regulation of the rat tissue type plasminogen activator gene: localization of DNA elements and nuclear factors mediating constitutive and cyclic AMP-induced expression.

  M Ohlsson, G Leonardsson, X C Jia, P Feng, T Ny
• Research Article

  Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.

  U M Wegenka, J Buschmann, C Lütticken, P C Heinrich, F Horn
• Research Article

  Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene.

  I T Chen, L A Chasin
• Research Article

  The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth.

  C A Finlay
• Research Article

  Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditions.

  S E Behrens, K Tyc, B Kastner, J Reichelt, R Lührmann
• Research Article

  Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.

  E P Sandgren, N C Luetteke, T H Qiu, R D Palmiter, R L Brinster, D C Lee
• Research Article

  Involvement of a C/EBP-like protein in the acquisition of responsiveness to glucocorticoid hormones during chick neural retina development.

  S Ben-Or, S Okret
• Research Article

  An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity.

  M Kenna, A Stevens, M McCammon, M G Douglas
• Research Article

  E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice.

  M P Kamps, D Baltimore
• Research Article

  Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A.

  I Bongarzone, N Monzini, M G Borrello, C Carcano, G Ferraresi, E Arighi, P Mondellini, G Della Porta, M A Pierotti
• Research Article

  Specific enzymatic dephosphorylation of the retinoblastoma protein.

  J W Ludlow, C L Glendening, D M Livingston, J A DeCarprio
• Research Article

  Timing of molecular events in meiosis in Saccharomyces cerevisiae: stable heteroduplex DNA is formed late in meiotic prophase.

  C Goyon, M Lichten
• Research Article

  Sequence-specific transcriptional activation by Myc and repression by Max.

  C Amin, A J Wagner, N Hay
• Research Article

  The effect on chromosome stability of deleting replication origins.

  A Dershowitz, C S Newlon
• Research Article

  Direct interaction of the tau 1 transactivation domain of the human glucocorticoid receptor with the basal transcriptional machinery.

  I J McEwan, A P Wright, K Dahlman-Wright, J Carlstedt-Duke, J A Gustafsson
• Research Article

  Binding of a sequence-specific single-stranded DNA-binding factor to the simian virus 40 core origin inverted repeat domain is cell cycle regulated.

  E P Carmichael, J M Roome, A F Wahl
• Research Article

  Developmental regulation and tissue distribution of the liver transcription factor LFB1 (HNF1) in Xenopus laevis.

  S Bartkowski, D Zapp, H Weber, G Eberle, C Zoidl, S Senkel, L Klein-Hitpass, G U Ryffel
• Research Article

  Induction of liver alpha-1 acid glycoprotein gene expression involves both positive and negative transcription factors.

  Y M Lee, W H Tsai, M Y Lai, D S Chen, S C Lee
• Research Article

  Hepatocyte-specific expression of the hepatitis B virus core promoter depends on both positive and negative regulation.

  W Guo, M Chen, T S Yen, J H Ou
• Research Article

  Two alleles of a developmentally regulated alpha-tubulin locus in Physarum polycephalum replicate on different schedules.

  D B Cunningham, W F Dove
• Research Article

  Estradiol-inducible squelching and cell growth arrest by a chimeric VP16-estrogen receptor expressed in Saccharomyces cerevisiae: suppression by an allele of PDR1.

  D M Gilbert, D M Heery, R Losson, P Chambon, Y Lemoine
• Research Article

  Hematopoietic commitment during embryonic stem cell differentiation in culture.

  G Keller, M Kennedy, T Papayannopoulou, M V Wiles
• Research Article

  A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity.

  L B Andersen, R Ballester, D A Marchuk, E Chang, D H Gutmann, A M Saulino, J Camonis, M Wigler, F S Collins
• Research Article

  DNA polymerases delta and epsilon are required for chromosomal replication in Saccharomyces cerevisiae.

  M E Budd, J L Campbell
• Research Article

  GCD11, a negative regulator of GCN4 expression, encodes the gamma subunit of eIF-2 in Saccharomyces cerevisiae.

  E M Hannig, A M Cigan, B A Freeman, T G Kinzy
• Research Article

  Suppressors of clathrin deficiency: overexpression of ubiquitin rescues lethal strains of clathrin-deficient Saccharomyces cerevisiae.

  K K Nelson, S K Lemmon
• Research Article

  Replication and mutagenesis of UV-damaged DNA templates in human and monkey cell extracts.

  M P Carty, J Hauser, A S Levine, K Dixon
• Research Article

  Concerted action of the transcriptional activators REB1, RAP1, and GCR1 in the high-level expression of the glycolytic gene TPI.

  E W Scott, H V Baker
• Research Article

  Unusually large telomeric repeats in the yeast Candida albicans.

  M J McEachern, J B Hicks
• Research Article

  Transcriptional activation by the adenovirus larger E1a product is mediated by members of the cellular transcription factor ATF family which can directly associate with E1a.

  B Chatton, J L Bocco, M Gaire, C Hauss, B Reimund, J Goetz, C Kedinger
• Research Article

  Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate.

  P Engler, A Weng, U Storb
• Research Article

  Characterization of the mouse beta maj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements.

  J Tantravahi, M Alvira, E Falck-Pedersen
• Research Article

  Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.

  N Nelson, M S Marks, P H Driggers, K Ozato
• Research Article

  fos/jun repression of cardiac-specific transcription in quiescent and growth-stimulated myocytes is targeted at a tissue-specific cis element.

  K McBride, L Robitaille, S Tremblay, S Argentin, M Nemer
• Research Article

  Profilaggrin is a major epidermal calcium-binding protein.

  N G Markova, L N Marekov, C C Chipev, S Q Gan, W W Idler, P M Steinert
• Research Article

  Splicing in Caenorhabditis elegans does not require an AG at the 3' splice acceptor site.

  R V Aroian, A D Levy, M Koga, Y Ohshima, J M Kramer, P W Sternberg
• Research Article

  Roles of multiple glucose transporters in Saccharomyces cerevisiae.

  C H Ko, H Liang, R F Gaber
• Research Article

  The REB1 site is an essential component of a terminator for RNA polymerase I in Saccharomyces cerevisiae.

  W H Lang, R H Reeder
• Research Article

  Differential activation of myc gene family members in hepatic carcinogenesis by closely related hepatitis B viruses.

  L J Hansen, B C Tennant, C Seeger, D Ganem
• Research Article

  GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression.

  V Lemarchandel, J Ghysdael, V Mignotte, C Rahuel, P H Roméo
• Research Article

  Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism.

  A Berghard, K Gradin, I Pongratz, M Whitelaw, L Poellinger
• Research Article

  A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter.

  S H Sims, Y Cha, M F Romine, P Q Gao, K Gottlieb, A B Deisseroth
• Research Article

  The cellular RNA-binding protein EAP recognizes a conserved stem-loop in the Epstein-Barr virus small RNA EBER 1.

  D P Toczyski, J A Steitz
• Research Article

  Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells.

  J J Ryan, R Danish, C A Gottlieb, M F Clarke
• Research Article

  Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts.

  E Ullu, K R Matthews, C Tschudi