Table of Contents

Research Article

• Research Article

  The requirement for yeast superoxide dismutase is bypassed through mutations in BSD2, a novel metal homeostasis gene.

  X F Liu, V C Culotta
• Research Article

  Identification of a cell-type-specific transcriptional repressor in the promoter region of the mouse hepatocyte growth factor gene.

  Y Liu, A B Beedle, L Lin, A W Bell, R Zarnegar
• Research Article

  A targeted-replacement system for identification of signals for de novo methylation in Neurospora crassa.

  V P Miao, M J Singer, M R Rountree, E U Selker
• Research Article

  Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors.

  P M Siegel, D L Dankort, W R Hardy, W J Muller
• Research Article

  Calcium inhibits epidermal growth factor-induced activation of p21ras in human primary keratinocytes.

  J P Medema, M W Sark, C Backendorf, J L Bos
• Research Article

  Genetic analysis of a transcriptional activation pathway by using hepatoma cell variants.

  G A Bulla, R E Fournier
• Research Article

  A novel synapse-associated noncoding RNA.

  M A Velleca, M C Wallace, J P Merlie
• Research Article

  Endogenous retinoid X receptors can function as hormone receptors in pituitary cells.

  K D Davis, T J Berrodin, J E Stelmach, J D Winkler, M A Lazar
• Research Article

  The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene.

  K Hahm, P Ernst, K Lo, G S Kim, C Turck, S T Smale
• Research Article

  Transcriptional regulation of the phosphoenolpyruvate carboxykinase gene by cooperation between hepatic nuclear factors.

  O Yanuka-Kashles, H Cohen, M Trus, A Aran, N Benvenisty, L Reshef
• Research Article

  A novel, cell-type-specific mechanism for estrogen receptor-mediated gene activation in the absence of an estrogen-responsive element.

  D A Sukovich, R Mukherjee, P A Benfield
• Research Article

  Reciprocal regulation of the Epstein-Barr virus BamHI-F promoter by EBNA-1 and an E2F transcription factor.

  N S Sung, J Wilson, M Davenport, N D Sista, J S Pagano
• Research Article

  Association of MEK1 with p21ras.GMPPNP is dependent on B-Raf.

  S A Moodie, M J Paris, W Kolch, A Wolfman
• Research Article

  The REC2 gene encodes the homologous pairing protein of Ustilago maydis.

  E B Kmiec, A Cole, W K Holloman
• Research Article

  p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly.

  R Foster, K Q Hu, D A Shaywitz, J Settleman
• Research Article

  Immortalization-susceptible elements and their binding factors mediate rejuvenation of regulation of the type I collagenase gene in simian virus 40 large T antigen-transformed immortal human fibroblasts.

  S Imai, T Fujino, S Nishibayashi, T Manabe, T Takano
• Research Article

  Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells.

  H Kiyokawa, V M Richon, R A Rifkind, P A Marks
• Research Article

  A monomeric derivative of the cellular transcription factor CREB functions as a constitutive activator.

  W Krajewski, K A Lee
• Research Article

  Analysis of period mRNA cycling in Drosophila head and body tissues indicates that body oscillators behave differently from head oscillators.

  P E Hardin
• Research Article

  Physical isolation of nascent RNA chains transcribed by RNA polymerase II: evidence for cotranscriptional splicing.

  J Wuarin, U Schibler
• Research Article

  Mutational analysis of the transcription activation domain of RelA: identification of a highly synergistic minimal acidic activation module.

  W S Blair, H P Bogerd, S J Madore, B R Cullen
• Research Article

  Virus-encoded cyclin.

  J U Jung, M Stäger, R C Desrosiers
• Research Article

  Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor.

  K A Schandel, D D Jenness
• Research Article

  Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein.

  Y W Kim, G A Otterson, R A Kratzke, A B Coxon, F J Kaye
• Research Article

  Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase.

  M Matsuoka, J Y Kato, R P Fisher, D O Morgan, C J Sherr
• Research Article

  Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression.

  W Zhong, J Mirkovitch, J E Darnell
• Research Article

  Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.

  J Tsukada, K Saito, W R Waterman, A C Webb, P E Auron
• Research Article

  Regulation of RAG-2 protein expression in avian thymocytes.

  S E Ferguson, M A Accavitti, D D Wang, C L Chen, C B Thompson
• Research Article

  Functional analysis of Csk in signal transduction through the B-cell antigen receptor.

  A Hata, H Sabe, T Kurosaki, M Takata, H Hanafusa
• Research Article

  Ets-1 activates the DRA promoter in B cells.

  N Jabrane-Ferrat, B M Peterlin
• Research Article

  Cap-dependent and cap-independent translation by internal initiation of mRNAs in cell extracts prepared from Saccharomyces cerevisiae.

  N Iizuka, L Najita, A Franzusoff, P Sarnow
• Research Article

  The basic helix-loop-helix protein upstream stimulating factor regulates the cardiac ventricular myosin light-chain 2 gene via independent cis regulatory elements.

  S Navankasattusas, M Sawadogo, M van Bilsen, C V Dang, K R Chien
• Research Article

  A homeodomain protein related to caudal regulates intestine-specific gene transcription.

  E Suh, L Chen, J Taylor, P G Traber
• Research Article

  Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun.

  E Cano, C A Hazzalin, L C Mahadevan
• Research Article

  A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins.

  A Cvekl, C M Sax, E H Bresnick, J Piatigorsky
• Research Article

  Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene.

  S C Sun, J Elwood, C Béraud, W C Greene
• Research Article

  cis-regulatory sequences responsible for alternative splicing of the Drosophila dopa decarboxylase gene.

  J Shen, J Hirsh
• Research Article

  Mapping an initiation region of DNA replication at a single-copy chromosomal locus in Drosophila melanogaster cells by two-dimensional gel methods and PCR-mediated nascent-strand analysis: multiple replication origins in a broad zone.

  T Shinomiya, S Ina
• Research Article

  A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transduction.

  S Takaki, H Kanazawa, M Shiiba, K Takatsu
• Research Article

  The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes.

  V Marechal, B Elenbaas, J Piette, J C Nicolas, A J Levine
• Research Article

  Comparison of DNA methylation patterns among mouse cell lines by restriction landmark genomic scanning.

  J Kawai, K Hirose, S Fushiki, S Hirotsune, N Ozawa, A Hara, Y Hayashizaki, S Watanabe
• Research Article

  Hierarchies of RNA-processing signals in a trypanosome surface antigen mRNA precursor.

  M Hug, H R Hotz, C Hartmann, C Clayton
• Research Article

  The human immunodeficiency virus type 1 Rev protein shuttles between the cytoplasm and nuclear compartments.

  K H Kalland, A M Szilvay, K A Brokstad, W Saetrevik, G Haukenes
• Research Article

  Identification and characterization by antisense oligonucleotides of exon and intron sequences required for splicing.

  Z Dominski, R Kole
• Research Article

  Differential effects of Cdc68 on cell cycle-regulated promoters in Saccharomyces cerevisiae.

  D Lycan, G Mikesell, M Bunger, L Breeden
• Research Article

  Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression.

  B H Jhun, D W Rose, B L Seely, L Rameh, L Cantley, A R Saltiel, J M Olefsky
• Research Article

  The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase.

  M Shirayama, Y Matsui, A Toh-E
• Research Article

  ralGDS family members interact with the effector loop of ras p21.

  A Kikuchi, S D Demo, Z H Ye, Y W Chen, L T Williams
• Research Article

  Active-site assembly and mode of DNA cleavage by Flp recombinase during full-site recombination.

  I Whang, J Lee, M Jayaram
• Research Article

  The SR protein B52/SRp55 is essential for Drosophila development.

  H Z Ring, J T Lis
• Research Article

  A highly conserved domain of RNA polymerase II shares a functional element with acidic activation domains of upstream transcription factors.

  H Xiao, J D Friesen, J T Lis
• Research Article

  The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells.

  H S Ip, D B Wilson, M Heikinheimo, Z Tang, C N Ting, M C Simon, J M Leiden, M S Parmacek
• Research Article

  Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor.

  E R Eldredge, G M Korf, T A Christensen, D C Connolly, M J Getz, N J Maihle
• Research Article

  Distinct protein forms are produced from alternatively spliced bicistronic glutamic acid decarboxylase mRNAs during development.

  G Szabo, Z Katarova, R Greenspan
• Research Article

  Fibroblast growth factor and cyclic AMP (cAMP) synergistically activate gene expression at a cAMP response element.

  Y Tan, K G Low, C Boccia, J Grossman, M J Comb
• Research Article

  Activation of the DNA-binding ability of human heat shock transcription factor 1 may involve the transition from an intramolecular to an intermolecular triple-stranded coiled-coil structure.

  J Zuo, R Baler, G Dahl, R Voellmy
• Research Article

  Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer.

  C V Gunther, B J Graves
• Research Article

  MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.

  K Kataoka, K T Fujiwara, M Noda, M Nishizawa
• Research Article

  Selection of new HSF1 and HSF2 DNA-binding sites reveals difference in trimer cooperativity.

  P E Kroeger, R I Morimoto
• Research Article

  Breakpoint junctions of chromosome 9p deletions in two human glioma cell lines.

  H M Pomykala, S K Bohlander, P L Broeker, O I Olopade, M O Díaz
• Research Article

  Identification of a putative RNA helicase (HRH1), a human homolog of yeast Prp22.

  Y Ono, M Ohno, Y Shimura
• Research Article

  Isolation of a thyroid hormone-responsive gene by immunoprecipitation of thyroid hormone receptor-DNA complexes.

  J Bigler, R N Eisenman
• Research Article

  Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the protein.

  K A Lillycrop, S J Dawson, J K Estridge, T Gerster, P Matthias, D S Latchman
• Research Article

  Functional conservation of multiple elements in yeast chromosomal replicators.

  H Rao, Y Marahrens, B Stillman
• Research Article

  Domain B of ARS307 contains two functional elements and contributes to chromosomal replication origin function.

  J F Theis, C S Newlon
• Research Article

  Cell transformation by fibroblast growth factors can be suppressed by truncated fibroblast growth factor receptors.

  Y Li, C Basilico, A Mansukhani
• Research Article

  SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex.

  D Staknis, R Reed