Table of Contents

Research Article

• Research Article

  Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression.

  A Sharma, R Stein
• Research Article

  A simple and efficient procedure for generating stable expression libraries by cDNA cloning in a retroviral vector.

  J R Rayner, T J Gonda
• Research Article

  Mechanisms of overlap formation in nonhomologous DNA end joining.

  P Pfeiffer, S Thode, J Hancke, W Vielmetter
• Research Article

  The mutant type 1 protein phosphatase encoded by glc7-1 from Saccharomyces cerevisiae fails to interact productively with the GAC1-encoded regulatory subunit.

  J S Stuart, D L Frederick, C M Varner, K Tatchell
• Research Article

  Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.

  E Gulbins, K M Coggeshall, C Langlet, G Baier, N Bonnefoy-Berard, P Burn, A Wittinghofer, S Katzav, A Altman
• Research Article

  A unique palindromic element mediates gamma interferon induction of mig gene expression.

  P Wong, C W Severns, N B Guyer, T M Wright
• Research Article

  The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.

  M Foiani, F Marini, D Gamba, G Lucchini, P Plevani
• Research Article

  Multiple silencer elements are involved in regulating the chicken vimentin gene.

  R J Garzon, Z E Zehner
• Research Article

  Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex.

  J L Wrana, H Tran, L Attisano, K Arora, S R Childs, J Massagué, M B O'Connor
• Research Article

  Two different sequence elements within exon 4 are necessary for calcitonin-specific splicing of the human calcitonin/calcitonin gene-related peptide I pre-mRNA.

  C C van Oers, G J Adema, H Zandberg, T C Moen, P D Baas
• Research Article

  Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells.

  A J Klingelhutz, S A Barber, P P Smith, K Dyer, J K McDougall
• Research Article

  Role of the histone amino termini in facilitated binding of a transcription factor, GAL4-AH, to nucleosome cores.

  M Vettese-Dadey, P Walter, H Chen, L J Juan, J L Workman
• Research Article

  Prokaryotic expression cloning of a novel human tyrosine kinase.

  J F Beeler, W J LaRochelle, M Chedid, S R Tronick, S A Aaronson
• Research Article

  Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pX.

  G Natoli, M L Avantaggiati, P Chirillo, A Costanzo, M Artini, C Balsano, M Levrero
• Research Article

  Endothelial-cell-specific regulation of von Willebrand factor gene expression.

  N Jahroudi, D C Lynch
• Research Article

  Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

  A Stacey, A Schnieke, J McWhir, J Cooper, A Colman, D W Melton
• Research Article

  Cloning and characterization of KNR4, a yeast gene involved in (1,3)-beta-glucan synthesis.

  Z Hong, P Mann, N H Brown, L E Tran, K J Shaw, R S Hare, B DiDomenico
• Research Article

  Retinoic acid represses Oct-3/4 gene expression through several retinoic acid-responsive elements located in the promoter-enhancer region.

  E Pikarsky, H Sharir, E Ben-Shushan, Y Bergman
• Research Article

  Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors.

  F A La Rosa, J W Pierce, G E Sonenshein
• Research Article

  Interactions among three proteins that specifically activate translation of the mitochondrial COX3 mRNA in Saccharomyces cerevisiae.

  N G Brown, M C Costanzo, T D Fox
• Research Article

  Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway.

  M S Hasson, D Blinder, J Thorner, D D Jenness
• Research Article

  Anisomycin and rapamycin define an area upstream of p70/85S6k containing a bifurcation to histone H3-HMG-like protein phosphorylation and c-fos-c-jun induction.

  E Kardalinou, N Zhelev, C A Hazzalin, L C Mahadevan
• Research Article

  Cdc42p GTPase is involved in controlling polarized cell growth in Schizosaccharomyces pombe.

  P J Miller, D I Johnson
• Research Article

  Specific expression of the human CD4 gene in mature CD4+ CD8- and immature CD4+ CD8+ T cells and in macrophages of transgenic mice.

  Z Hanna, C Simard, A Laperrière, P Jolicoeur
• Research Article

  Ig alpha and Ig beta are functionally homologous to the signaling proteins of the T-cell receptor.

  A L Burkhardt, T Costa, Z Misulovin, B Stealy, J B Bolen, M C Nussenzweig
• Research Article

  Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors.

  R D Mosteller, J Han, D Broek
• Research Article

  Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors.

  L A Quilliam, K Kato, K M Rabun, M M Hisaka, S Y Huff, S Campbell-Burk, C J Der
• Research Article

  Characterization of a negative retinoic acid response element in the murine Oct4 promoter.

  J Schoorlemmer, A van Puijenbroek, M van Den Eijnden, L Jonk, C Pals, W Kruijer
• Research Article

  The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes.

  J H Lammers, H H Offenberg, M van Aalderen, A C Vink, A J Dietrich, C Heyting
• Research Article

  Intracellular association of the protein product of the c-myc oncogene with the TATA-binding protein.

  S Maheswaran, H Lee, G E Sonenshein
• Research Article

  Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors.

  C Y Wang, A G Bassuk, L H Boise, C B Thompson, R Bravo, J M Leiden
• Research Article

  Glucose repression of yeast mitochondrial transcription: kinetics of derepression and role of nuclear genes.

  T L Ulery, S H Jang, J A Jaehning
• Research Article

  Physical and functional interaction between wild-type p53 and mdm2 proteins.

  D S Haines, J E Landers, L J Engle, D L George
• Research Article

  Pigment-cell-specific genes from fibroblasts are transactivated after chromosomal transfer into melanoma cells.

  T P Powers, T B Shows, R L Davidson
• Research Article

  Stably integrated mouse mammary tumor virus long terminal repeat DNA requires the octamer motifs for basal promoter activity.

  E Buetti
• Research Article

  DNA repair defects associated with chromosomal translocation breaksite regions.

  E J Beecham, G M Jones, C Link, K Huppi, M Potter, J F Mushinski, V A Bohr
• Research Article

  Activation of phospholipase C-gamma 1 through transfected platelet-derived growth factor receptor enhances interleukin 2 production upon antigen stimulation in a T-cell line.

  H Nakano, H Ohno, T Saito
• Research Article

  Positive regulatory elements (HF-1a and HF-1b) and a novel negative regulatory element (HF-3) mediate ventricular muscle-specific expression of myosin light-chain 2-luciferase fusion genes in transgenic mice.

  K J Lee, R Hickey, H Zhu, K R Chien
• Research Article

  RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.

  W Reith, C Ucla, E Barras, A Gaud, B Durand, C Herrero-Sanchez, M Kobr, B Mach
• Research Article

  HEN1 encodes a 20-kilodalton phosphoprotein that binds an extended E-box motif as a homodimer.

  L Brown, R Baer
• Research Article

  Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins.

  H L Hsu, L Huang, J T Tsan, W Funk, W E Wright, J S Hu, R E Kingston, R Baer
• Research Article

  tRNA genes as transcriptional repressor elements.

  M W Hull, J Erickson, M Johnston, D R Engelke
• Research Article

  Homologous, homeologous, and illegitimate repair of double-strand breaks during transformation of a wild-type strain and a rad52 mutant strain of Saccharomyces cerevisiae.

  C Mezard, A Nicolas
• Research Article

  Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events.

  K M Kramer, J A Brock, K Bloom, J K Moore, J E Haber
• Research Article

  Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster.

  I Reveillaud, J Phillips, B Duyf, A Hilliker, A Kongpachith, J E Fleming
• Research Article

  Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase.

  M Autero, J Saharinen, T Pessa-Morikawa, M Soula-Rothhut, C Oetken, M Gassmann, M Bergman, K Alitalo, P Burn, C G Gahmberg
• Research Article

  HLA class I heavy-chain gene promoter elements mediating synergy between tumor necrosis factor and interferons.

  D R Johnson, J S Pober
• Research Article

  The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex.

  S Obert, R J O'Connor, S Schmid, P Hearing
• Research Article

  Polypurine sequences within a downstream exon function as a splicing enhancer.

  K Tanaka, A Watakabe, Y Shimura
• Research Article

  Xenopus gamma-crystallin gene expression: evidence that the gamma-crystallin gene family is transcribed in lens and nonlens tissues.

  B D Smolich, S K Tarkington, M S Saha, R M Grainger
• Research Article

  A factor induced by differentiation signals in cells of the macrophage lineage binds to the gamma interferon activation site.

  A Eilers, M Baccarini, F Horn, R A Hipskind, C Schindler, T Decker
• Research Article

  Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency.

  C Béraud, S C Sun, P Ganchi, D W Ballard, W C Greene
• Research Article

  A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor.

  Y H Lee, M Yano, S Y Liu, E Matsunaga, P F Johnson, F J Gonzalez
• Research Article

  ATBF1, a multiple-homeodomain zinc finger protein, selectively down-regulates AT-rich elements of the human alpha-fetoprotein gene.

  H Yasuda, A Mizuno, T Tamaoki, T Morinaga
• Research Article

  Purification of an oligo(dG).oligo(dC)-binding sea urchin nuclear protein, suGF1: a family of G-string factors involved in gene regulation during development.

  J Hapgood, D Patterton
• Research Article

  suGF1 binds in the major groove of its oligo(dG).oligo(dC) recognition sequence and is excluded by a positioned nucleosome core.

  D Patterton, J Hapgood
• Research Article

  High-resolution methylation analysis of the human hypoxanthine phosphoribosyltransferase gene 5' region on the active and inactive X chromosomes: correlation with binding sites for transcription factors.

  I K Hornstra, T P Yang
• Research Article

  Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor.

  B Samal, Y Sun, G Stearns, C Xie, S Suggs, I McNiece
• Research Article

  Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export.

  S Sapperstein, C Berkower, S Michaelis
• Research Article

  Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences.

  H Leung, N Maizels
• Research Article

  The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo.

  Y Minami, Y Kimura, H Kawasaki, K Suzuki, I Yahara
• Research Article

  Nature and distribution of chromosomal intertwinings in Saccharomyces cerevisiae.

  R M Spell, C Holm
• Research Article

  Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins.

  E Petricoin, M David, H Fang, P Grimley, A C Larner, S Vande Pol
• Research Article

  The Drosophila l(2)35Ba/nocA gene encodes a putative Zn finger protein involved in the development of the embryonic brain and the adult ocellar structures.

  P Y Cheah, Y B Meng, X Yang, D Kimbrell, M Ashburner, W Chia
• Research Article

  Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system.

  H Harada, E Takahashi, S Itoh, K Harada, T A Hori, T Taniguchi
• Research Article

  Cloning and characterization of centromeric DNA from Neurospora crassa.

  M Centola, J Carbon
• Research Article

  Analysis of an origin of DNA amplification in Sciara coprophila by a novel three-dimensional gel method.

  C Liang, S A Gerbi