Table of Contents

Research Article

• Research Article

  Identification and characterization of Drosophila relatives of the yeast transcriptional activator SNF2/SWI2.

  L K Elfring, R Deuring, C M McCallum, C L Peterson, J W Tamkun
• Research Article

  Multiple cis-acting targeting sequences are required for orb mRNA localization during Drosophila oogenesis.

  V Lantz, P Schedl
• Research Article

  Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic mice.

  A R Brooks, B P Nagy, S Taylor, W S Simonet, J M Taylor, B Levy-Wilson
• Research Article

  A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation.

  D L Barber, J C DeMartino, M O Showers, A D D'Andrea
• Research Article

  A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells.

  G D Longmore, P N Pharr, H F Lodish
• Research Article

  Overexpression of C-terminally but not N-terminally truncated Myb induces fibrosarcomas: a novel nonhematopoietic target cell for the myb oncogene.

  R D Press, E P Reddy, D L Ewert
• Research Article

  A gene involved in control of human cellular senescence on human chromosome 1q.

  P J Hensler, L A Annab, J C Barrett, O M Pereira-Smith
• Research Article

  Subcellular locations of MOD5 proteins: mapping of sequences sufficient for targeting to mitochondria and demonstration that mitochondrial and nuclear isoforms commingle in the cytosol.

  M Boguta, L A Hunter, W C Shen, E C Gillman, N C Martin, A K Hopper
• Research Article

  The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence.

  N Méthot, A Pause, J W Hershey, N Sonenberg
• Research Article

  A nuclear encoded tRNA of Trypanosoma brucei is imported into mitochondria.

  A Schneider, J Martin, N Agabian
• Research Article

  Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha.

  B F Tate, G Allenby, R Janocha, S Kazmer, J Speck, L J Sturzenbecker, P Abarzúa, A A Levin, J F Grippo
• Research Article

  The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins.

  T G Lee, N Tang, S Thompson, J Miller, M G Katze
• Research Article

  Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity.

  M Russell, S Winitz, G L Johnson
• Research Article

  The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.

  M Selvakumaran, H K Lin, R T Sjin, J C Reed, D A Liebermann, B Hoffman
• Research Article

  The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth.

  Q Zhan, K A Lord, I Alamo, M C Hollander, F Carrier, D Ron, K W Kohn, B Hoffman, D A Liebermann, A J Fornace
• Research Article

  Activation of the Ras/mitogen-activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3-L1 adipocytes.

  N van den Berghe, D M Ouwens, J A Maassen, M G van Mackelenbergh, H C Sips, H M Krans
• Research Article

  A segment of mRNA encoding the leader peptide of the CPA1 gene confers repression by arginine on a heterologous yeast gene transcript.

  P Delbecq, M Werner, A Feller, R K Filipkowski, F Messenguy, A Piérard
• Research Article

  NHP6A and NHP6B, which encode HMG1-like proteins, are candidates for downstream components of the yeast SLT2 mitogen-activated protein kinase pathway.

  C Costigan, D Kolodrubetz, M Snyder
• Research Article

  Targeting frequency for deletion vectors in embryonic stem cells.

  H Zhang, P Hasty, A Bradley
• Research Article

  Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes.

  R Philip, E Brunette, L Kilinski, D Murugesh, M A McNally, K Ucar, J Rosenblatt, T B Okarma, J S Lebkowski
• Research Article

  Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine.

  H H van Es, S Karcz, F Chu, A F Cowman, S Vidal, P Gros, E Schurr
• Research Article

  Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia.

  D D Wright, B M Sefton, M P Kamps
• Research Article

  A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor.

  J McGuire, M L Whitelaw, I Pongratz, J A Gustafsson, L Poellinger
• Research Article

  rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells.

  T Nishiyama, T Sasaki, K Takaishi, M Kato, H Yaku, K Araki, Y Matsuura, Y Takai
• Research Article

  Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney.

  C S Lin, W Shen, Z P Chen, Y H Tu, P Matsudaira
• Research Article

  Loss of p53 protein during radiation transformation of primary human mammary epithelial cells.

  D E Wazer, Q Chu, X L Liu, Q Gao, H Safaii, V Band
• Research Article

  Non-Mendelian inheritance of macronuclear mutations is gene specific in Paramecium tetraurelia.

  J M Scott, K Mikami, C L Leeck, J D Forney
• Research Article

  Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.

  A R Zinn, R K Alagappan, L G Brown, I Wool, D C Page
• Research Article

  Continued functioning of the secretory pathway is essential for ribosome synthesis.

  K Mizuta, J R Warner
• Research Article

  The Aspergillus nidulans abaA gene encodes a transcriptional activator that acts as a genetic switch to control development.

  A Andrianopoulos, W E Timberlake
• Research Article

  Transcription inhibits the replication of autonomously replicating plasmids in human cells.

  S B Haase, S S Heinzel, M P Calos
• Research Article

  Characterization of cis-acting elements in light regulation of the nuclear gene encoding the A subunit of chloroplast isozymes of glyceraldehyde-3-phosphate dehydrogenase from Arabidopsis thaliana.

  T R Conley, S C Park, H B Kwon, H P Peng, M C Shih
• Research Article

  MCM1 point mutants deficient in expression of alpha-specific genes: residues important for interaction with alpha 1.

  L Bruhn, G F Sprague
• Research Article

  Cellular protein interactions with herpes simplex virus type 1 oriS.

  C E Dabrowski, P J Carmillo, P A Schaffer
• Research Article

  Bcl-2 blocks p53-dependent apoptosis.

  S K Chiou, L Rao, E White
• Research Article

  Molecular genetic analyses of a 376-kilodalton Golgi complex membrane protein (giantin)

  H P Seelig, P Schranz, H Schröter, C Wiemann, G Griffiths, M Renz
• Research Article

  Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta.

  P Hu, J Schlessinger
• Research Article

  Developmental and cell type specificity of LINE-1 expression in mouse testis: implications for transposition.

  D Branciforte, S L Martin
• Research Article

  Purification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcription.

  S K Hansen, P A Baeuerle, F Blasi
• Research Article

  The human beta 2 integrin CD18 promoter consists of two inverted Ets cis elements.

  E P Böttinger, C S Shelley, O C Farokhzad, M A Arnaout
• Research Article

  Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron.

  C M Grant, P F Miller, A G Hinnebusch
• Research Article

  Assembly of mitochondrial ribonucleoprotein complexes involves specific guide RNA (gRNA)-binding proteins and gRNA domains but does not require preedited mRNA.

  L K Read, H U Göringer, K Stuart
• Research Article

  Faithful degradation of soybean rbcS mRNA in vitro.

  M M Tanzer, R B Meagher
• Research Article

  Stimulation of polyomavirus DNA replication by wild-type p53 through the DNA-binding site.

  T Kanda, K Segawa, N Ohuchi, S Mori, Y Ito
• Research Article

  His-154 is involved in the linkage of the Saccharomyces cerevisiae L-A double-stranded RNA virus Gag protein to the cap structure of mRNAs and is essential for M1 satellite virus expression.

  A Blanc, J C Ribas, R B Wickner, N Sonenberg
• Research Article

  The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity.

  A Klippel, J A Escobedo, M Hirano, L T Williams
• Research Article

  Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen.

  M T Sáenz Robles, H Symonds, J Chen, T Van Dyke
• Research Article

  Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles.

  M Yoneda, T Miyatake, G Attardi
• Research Article

  Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase.

  J Y Kato, M Matsuoka, D K Strom, C J Sherr
• Research Article

  In vitro mutagenesis of Caenorhabditis elegans cuticle collagens identifies a potential subtilisin-like protease cleavage site and demonstrates that carboxyl domain disulfide bonding is required for normal function but not assembly.

  J Yang, J M Kramer
• Research Article

  Modulating the potency of an activator in a yeast in vitro transcription system.

  Y Ohashi, J M Brickman, E Furman, B Middleton, M Carey
• Research Article

  Identification and characterization of a novel yeast gene: the YGP1 gene product is a highly glycosylated secreted protein that is synthesized in response to nutrient limitation.

  M Destruelle, H Holzer, D J Klionsky
• Research Article

  The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix.

  D G Overdier, A Porcella, R H Costa
• Research Article

  A unique subpopulation of murine DNA polymerase alpha/primase specifically interacts with polyomavirus T antigen and stimulates DNA replication.

  K Moses, C Prives
• Research Article

  Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

  Z Songyang, S E Shoelson, J McGlade, P Olivier, T Pawson, X R Bustelo, M Barbacid, H Sabe, H Hanafusa, T Yi
• Research Article

  FTZ-F1-related orphan receptors in Xenopus laevis: transcriptional regulators differentially expressed during early embryogenesis.

  H Ellinger-Ziegelbauer, A K Hihi, V Laudet, H Keller, W Wahli, C Dreyer
• Research Article

  Identical components of yeast transcription factor IIIB are required and sufficient for transcription of TATA box-containing and TATA-less genes.

  C A Joazeiro, G A Kassavetis, E P Geiduschek
• Research Article

  Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice.

  M I Ramirez, D Karaoglu, D Haro, C Barillas, R Bashirzadeh, G Gil
• Research Article

  Histone H1 expressed in Saccharomyces cerevisiae binds to chromatin and affects survival, growth, transcription, and plasmid stability but does not change nucleosomal spacing.

  C Linder, F Thoma