Table of Contents

Research Article

• Research Article

  Induction of the rat prodynorphin gene through Gs-coupled receptors may involve phosphorylation-dependent derepression and activation.

  J Collins-Hicok, L Lin, C Spiro, P J Laybourn, R Tschumper, B Rapacz, C T McMurray
• Research Article

  Biological activity of the growth factor-induced cytokine N51: structure-function analysis using N51/Interleukin-8 chimeric molecules.

  J N Heinrich, E C O'Rourke, L Chen, H Gray, K S Dorfman, R Bravo
• Research Article

  The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lck.

  M Raab, M Yamamoto, C E Rudd
• Research Article

  xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity.

  C H Hu, B McStay, S W Jeong, R H Reeder
• Research Article

  Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase.

  B J Mayer, D Baltimore
• Research Article

  Facilitated folding of actins and tubulins occurs via a nucleotide-dependent interaction between cytoplasmic chaperonin and distinctive folding intermediates.

  R Melki, N J Cowan
• Research Article

  Suppression of yeast RNA polymerase III mutations by FHL1, a gene coding for a fork head protein involved in rRNA processing.

  S Hermann-Le Denmat, M Werner, A Sentenac, P Thuriaux
• Research Article

  Definition of a lipopolysaccharide-responsive element in the 5'-flanking regions of MuRantes and crg-2.

  H S Shin, B E Drysdale, M L Shin, P W Noble, S N Fisher, W A Paznekas
• Research Article

  Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits.

  A M Brown, M W Linhoff, B Stein, K L Wright, A S Baldwin, P V Basta, J P Ting
• Research Article

  Cloning and characterization of a novel RNA involved in cellular growth regulation.

  B M Moats-Staats, H W Jarvis, A J D'Ercole, A D Stiles
• Research Article

  Poly(A) polymerase contains multiple functional domains.

  T Raabe, K G Murthy, J L Manley
• Research Article

  Characterization of tobacco protein kinase NPK5, a homolog of Saccharomyces cerevisiae SNF1 that constitutively activates expression of the glucose-repressible SUC2 gene for a secreted invertase of S. cerevisiae.

  T Muranaka, H Banno, Y Machida
• Research Article

  In vitro study of processing of the intron-encoded U16 small nucleolar RNA in Xenopus laevis.

  E Caffarelli, M Arese, B Santoro, P Fragapane, I Bozzoni
• Research Article

  Developmental gene expression in Leishmania donovani: differential cloning and analysis of an amastigote-stage-specific gene.

  H Charest, G Matlashewski
• Research Article

  Activation of the glycoprotein hormone alpha-subunit promoter by a LIM-homeodomain transcription factor.

  M S Roberson, W E Schoderbek, G Tremml, R A Maurer
• Research Article

  Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly.

  D Staknis, R Reed
• Research Article

  Direct activation of phospholipase C-gamma by fibroblast growth factor receptor is not required for mesoderm induction in Xenopus animal caps.

  A J Muslin, K G Peters, L T Williams
• Research Article

  Mediators of activation of fushi tarazu gene transcription by BmFTZ-F1.

  F Q Li, H Ueda, S Hirose
• Research Article

  The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivo.

  M G Goebl, L Goetsch, B Byers
• Research Article

  Nuclear localization and cell cycle regulation of a murine protein tyrosine phosphatase.

  U Tillmann, J Wagner, D Boerboom, H Westphal, M L Tremblay
• Research Article

  DNA-binding-defective mutants of the Epstein-Barr virus lytic switch activator Zta transactivate with altered specificities.

  E K Flemington, J P Lytle, C Cayrol, A M Borras, S H Speck
• Research Article

  Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC.

  G Lagna, R Kovelman, J Sukegawa, R G Roeder
• Research Article

  Two distinctly regulated genes are required for ferric reduction, the first step of iron uptake in Saccharomyces cerevisiae.

  E Georgatsou, D Alexandraki
• Research Article

  Internally located and oppositely oriented polymerase II promoters direct convergent transcription of a LINE-like retroelement, the Dictyostelium repetitive element, from Dictyostelium discoideum.

  G Schumann, I Zündorf, J Hofmann, R Marschalek, T Dingermann
• Research Article

  A novel mechanism of Ha-ras oncogene action: regulation of fibronectin mRNA levels by a nuclear posttranscriptional event.

  L A Chandler, C P Ehretsmann, S Bourgeois
• Research Article

  The Mauriceville plasmid of Neurospora spp. uses novel mechanisms for initiating reverse transcription in vivo.

  J C Kennell, H Wang, A M Lambowitz
• Research Article

  Positive regulators of the lineage-specific transcription factor GATA-1 in differentiating erythroid cells.

  M H Baron, S M Farrington
• Research Article

  A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription.

  C Grépin, L Dagnino, L Robitaille, L Haberstroh, T Antakly, M Nemer
• Research Article

  An estrogen-inducible protein binds specifically to a sequence in the 3' untranslated region of estrogen-stabilized vitellogenin mRNA.

  R E Dodson, D J Shapiro
• Research Article

  MOT2 encodes a negative regulator of gene expression that affects basal expression of pheromone-responsive genes in Saccharomyces cerevisiae.

  R M Cade, B Errede
• Research Article

  The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes.

  K Irie, K Yamaguchi, K Kawase, K Matsumoto
• Research Article

  The Glc7 type 1 protein phosphatase of Saccharomyces cerevisiae is required for cell cycle progression in G2/M.

  N Hisamoto, K Sugimoto, K Matsumoto
• Research Article

  The Drosophila nuclear receptors FTZ-F1 alpha and FTZ-F1 beta compete as monomers for binding to a site in the fushi tarazu gene.

  C K Ohno, H Ueda, M Petkovich
• Research Article

  Species-specific functional interactions of DNA polymerase alpha-primase with simian virus 40 (SV40) T antigen require SV40 origin DNA.

  C Schneider, K Weisshart, L A Guarino, I Dornreiter, E Fanning
• Research Article

  The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.

  U M Wegenka, C Lütticken, J Buschmann, J Yuan, F Lottspeich, W Müller-Esterl, C Schindler, E Roeb, P C Heinrich, F Horn
• Research Article

  The C-terminal domain of Saccharomyces cerevisiae DNA topoisomerase II.

  P R Caron, P Watt, J C Wang
• Research Article

  Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation.

  C R Vazquez de Aldana, A G Hinnebusch
• Research Article

  Genetic identification of residues involved in association of alpha and beta G-protein subunits.

  M Whiteway, K L Clark, E Leberer, D Dignard, D Y Thomas
• Research Article

  DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma.

  R A Bailly, R Bosselut, J Zucman, F Cormier, O Delattre, M Roussel, G Thomas, J Ghysdael
• Research Article

  PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.

  S C Bae, E Ogawa, M Maruyama, H Oka, M Satake, K Shigesada, N A Jenkins, D J Gilbert, N G Copeland, Y Ito
• Research Article

  Analysis of the role of the Shc and Grb2 proteins in signal transduction by the v-ErbB protein.

  S Meyer, K LaBudda, J McGlade, M J Hayman
• Research Article

  Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia.

  I Faus, H J Hsu, E Fuchs
• Research Article

  Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines.

  S Miyamoto, P J Chiao, I M Verma
• Research Article

  The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1.

  P Shore, A D Sharrocks
• Research Article

  ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development.

  M Lopez, P Oettgen, Y Akbarali, U Dendorfer, T A Libermann
• Research Article

  The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor.

  S Dou, X Zeng, P Cortes, H Erdjument-Bromage, P Tempst, T Honjo, L D Vales
• Research Article

  An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells.

  T T Nugroho, M D Mendenhall
• Research Article

  Ligand modulates the conversion of DNA-bound vitamin D3 receptor (VDR) homodimers into VDR-retinoid X receptor heterodimers.

  B Cheskis, L P Freedman
• Research Article

  The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization.

  C J Stefan, K J Blumer
• Research Article

  A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4.

  J Weinstein, F W Jacobsen, J Hsu-Chen, T Wu, L G Baum
• Research Article

  Specific DNA recognition and intersite spacing are critical for action of the bicoid morphogen.

  S D Hanes, G Riddihough, D Ish-Horowicz, R Brent
• Research Article

  The DNA-bending protein HMG-1 enhances progesterone receptor binding to its target DNA sequences.

  S A Oñate, P Prendergast, J P Wagner, M Nissen, R Reeves, D E Pettijohn, D P Edwards
• Research Article

  The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase.

  P H Stein, J D Fraser, A Weiss
• Research Article

  DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein.

  T Inaba, L H Shapiro, T Funabiki, A E Sinclair, B G Jones, R A Ashmun, A T Look
• Research Article

  Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae.

  E L Ivanov, N Sugawara, C I White, F Fabre, J E Haber
• Research Article

  Imprecise excision of the Caenorhabditis elegans transposon Tc1 creates functional 5' splice sites.

  B Carr, P Anderson
• Research Article

  Intron definition in splicing of small Drosophila introns.

  M Talerico, S M Berget
• Research Article

  The yeast UME5 gene regulates the stability of meiotic mRNAs in response to glucose.

  R T Surosky, R Strich, R E Esposito
• Research Article

  Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle.

  A Shisheva, T C Südhof, M P Czech
• Research Article

  Endocrine and neurogenic regulation of the orphan nuclear receptors Nur77 and Nurr-1 in the adrenal glands.

  I J Davis, L F Lau
• Research Article

  Transcriptional activation by herpes simplex virus type 1 VP16 in vitro and its inhibition by oligopeptides.

  T J Wu, G Monokian, D F Mark, C R Wobbe
• Research Article

  Melanocyte-specific gene expression: role of repression and identification of a melanocyte-specific factor, MSF.

  U Yavuzer, C R Goding
• Research Article

  Novel muscle-specific enhancer sequences upstream of the cardiac actin gene.

  C Biben, B J Kirschbaum, I Garner, M Buckingham
• Research Article

  Glucagon gene expression is negatively regulated by hepatocyte nuclear factor 3 beta.

  J Philippe, C Morel, V R Prezioso
• Research Article

  Chromosomal DNA replication initiates at the same origins in meiosis and mitosis.

  I Collins, C S Newlon