Table of Contents

Articles

• Journal Article | Research Support, Non-U.S. Gov't

  The polycomb group protein complex of Drosophila melanogaster has different compositions at different target genes.

  H Strutt, R Paro
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Mutational analysis of the D1/E1 core helices and the conserved N-terminal region of yeast transcription factor IIB (TFIIB): identification of an N-terminal mutant that stabilizes TATA-binding protein-TFIIB-DNA complexes.

  C S Bangur, T S Pardee, A S Ponticelli
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains.

  S Chou, K Struhl
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes.

  D Tantin, A Kansal, M Carey
• Journal Article | Research Support, Non-U.S. Gov't

  Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation.

  R W Deed, E Hara, G T Atherton, G Peters, J D Norton
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Initiation of DNA interstrand cross-link repair in humans: the nucleotide excision repair system makes dual incisions 5' to the cross-linked base and removes a 22- to 28-nucleotide-long damage-free strand.

  T Bessho, D Mu, A Sancar
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  A disease-associated G5703A mutation in human mitochondrial DNA causes a conformational change and a marked decrease in steady-state levels of mitochondrial tRNA(Asn).

  H Hao, C T Moraes
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Hepatitis B virus X protein induces RNA polymerase III-dependent gene transcription and increases cellular TATA-binding protein by activating the Ras signaling pathway.

  H D Wang, A Trivedi, D L Johnson
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology.

  C J Bonangelino, N L Catlett, L S Weisman
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Transmembrane glycoprotein gp150 is a substrate for receptor tyrosine phosphatase DPTP10D in Drosophila cells.

  S J Fashena, K Zinn
• Journal Article

  Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance.

  J M Murray, H D Lindsay, C A Munday, A M Carr
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Binding of eukaryotic translation initiation factor 4E (eIF4E) to eIF4G represses translation of uncapped mRNA.

  S Z Tarun, A B Sachs
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Differential recognition of liganded and unliganded thyroid hormone receptor by retinoid X receptor regulates transcriptional repression.

  J Zhang, I Zamir, M A Lazar
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Promoter activity of Tat at steps subsequent to TATA-binding protein recruitment.

  H Xiao, J T Lis, K T Jeang
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation.

  A Richardson, R K Malik, J D Hildebrand, J T Parsons
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't

  Identification and characterization of XPC-binding domain of hHR23B.

  C Masutani, M Araki, K Sugasawa, P J van der Spek, A Yamada, A Uchida, T Maekawa, D Bootsma, J H Hoeijmakers, F Hanaoka
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't

  Two human homologs of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity.

  K Sugasawa, J M Ng, C Masutani, T Maekawa, A Uchida, P J van der Spek, A P Eker, S Rademakers, C Visser, A Aboussekhra, R D Wood, F Hanaoka, D Bootsma, J H Hoeijmakers
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution.

  W Li, P Swanson, S Desiderio
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't

  Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A.

  H Imataka, N Sonenberg
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  A heterologous maize rpoB editing site is recognized by transgenic tobacco chloroplasts.

  M L Reed, M R Hanson
• In Vitro | Journal Article

  Sin mutations of histone H3: influence on nucleosome core structure and function.

  H Kurumizaka, A P Wolffe
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB.

  P L Jones, D Ping, J M Boss
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.

  L Fernandes, C Rodrigues-Pousada, K Struhl
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Subunit composition determines E2F DNA-binding site specificity.

  Y Tao, R F Kassatly, W D Cress, J M Horowitz
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  The Saccharomyces cerevisiae Hap5p homolog from fission yeast reveals two conserved domains that are essential for assembly of heterotetrameric CCAAT-binding factor.

  D S McNabb, K A Tseng, L Guarente
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S.

  Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein.

  J M Yingling, M B Datto, C Wong, J P Frederick, N T Liberati, X F Wang
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  SSP1, a gene necessary for proper completion of meiotic divisions and spore formation in Saccharomyces cerevisiae.

  D K Nag, M P Koonce, J Axelrod
• Journal Article

  Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

  A Kelekar, B S Chang, J E Harlan, S W Fesik, C B Thompson
• Comparative Study | Journal Article

  Npp106p, a Schizosaccharomyces pombe nucleoporin similar to Saccharomyces cerevisiae Nic96p, functionally interacts with Rae1p in mRNA export.

  J H Yoon, W A Whalen, A Bharathi, R Shen, R Dhar
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  The yeast silent information regulator Sir4p anchors and partitions plasmids.

  A Ansari, M R Gartenberg
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S.

  Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes.

  M T Hess, D Gunz, N Luneva, N E Geacintov, H Naegeli
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  DNA in transcriptionally silent chromatin assumes a distinct topology that is sensitive to cell cycle progression.

  X Bi, J R Broach
• Journal Article | Research Support, Non-U.S. Gov't

  Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.

  T Gautier, T Bergès, D Tollervey, E Hurt
• Journal Article | Research Support, Non-U.S. Gov't

  U1 small nuclear RNA-promoted exon selection requires a minimal distance between the position of U1 binding and the 3' splice site across the exon.

  D Y Hwang, J B Cohen
• Journal Article | Research Support, Non-U.S. Gov't

  Concerted activity of host cell factor subregions in promoting stable VP16 complex assembly and preventing interference by the acidic activation domain.

  S LaBoissière, S Walker, P O'Hare
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  A tetratricopeptide repeat mutation in yeast transcription factor IIIC131 (TFIIIC131) facilitates recruitment of TFIIB-related factor TFIIIB70.

  R D Moir, I Sethy-Coraci, K Puglia, M D Librizzi, I M Willis
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Novel receptor interaction and repression domains in the orphan receptor SHP.

  W Seol, M Chung, D D Moore
• Comparative Study | In Vitro | Journal Article | Research Support, Non-U.S. Gov't

  The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.

  K H Nielsen, A G Papageorge, W C Vass, B M Willumsen, D R Lowy
• In Vitro | Journal Article

  A histone octamer blocks branch migration of a Holliday junction.

  M Grigoriev, P Hsieh
• Journal Article | Research Support, U.S. Gov't, Non-P.H.S.

  Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase.

  S J Xia, M A Shammas, R J Shmookler Reis
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Architecture of the yeast origin recognition complex bound to origins of DNA replication.

  D G Lee, S P Bell
• Journal Article | Research Support, Non-U.S. Gov't

  The amino terminus of the F1-ATPase beta-subunit precursor functions as an intramolecular chaperone to facilitate mitochondrial protein import.

  P Hájek, J Y Koh, L Jones, D M Bedwell
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  3' processing of human pre-U2 small nuclear RNA: a base-pairing interaction between the 3' extension of the precursor and an internal region.

  Q Huang, M R Jacobson, T Pederson
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  POU domain transcription factor brain 4 confers pancreatic alpha-cell-specific expression of the proglucagon gene through interaction with a novel proximal promoter G1 element.

  M A Hussain, J Lee, C P Miller, J F Habener
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S.

  Constitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression.

  J S Qi, V Desai-Yajnik, Y Yuan, H H Samuels
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Functional interaction of a novel cellular protein with the papillomavirus E2 transactivation domain.

  D E Breiding, F Sverdrup, M J Grossel, N Moscufo, W Boonchai, E J Androphy
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S.

  p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.

  L J Ko, S Y Shieh, X Chen, L Jayaraman, K Tamai, Y Taya, C Prives, Z Q Pan
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Interaction of yeast repressor-activator protein Ume6p with glycogen synthase kinase 3 homolog Rim11p.

  K Malathi, Y Xiao, A P Mitchell
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Regulatory sequences for the amplification and replication of the ribosomal DNA minichromosome in Tetrahymena thermophila.

  P Blomberg, C Randolph, C H Yao, M C Yao
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  A role for cyclin D3 in the endomitotic cell cycle.

  J M Zimmet, D Ladd, C W Jackson, P E Stenberg, K Ravid
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Mutations in the hrp48 gene, which encodes a Drosophila heterogeneous nuclear ribonucleoprotein particle protein, cause lethality and developmental defects and affect P-element third-intron splicing in vivo.

  L E Hammond, D Z Rudner, R Kanaar, D C Rio
• Journal Article | Research Support, Non-U.S. Gov't

  E2F activity is regulated by cell cycle-dependent changes in subcellular localization.

  R Verona, K Moberg, S Estes, M Starz, J P Vernon, J A Lees
• Journal Article | Research Support, Non-U.S. Gov't

  Fal1p is an essential DEAD-box protein involved in 40S-ribosomal-subunit biogenesis in Saccharomyces cerevisiae.

  D Kressler, J de la Cruz, M Rojo, P Linder
• In Vitro | Journal Article | Research Support, U.S. Gov't, P.H.S.

  OCA-B is a functional analog of VP16 but targets a separate surface of the Oct-1 POU domain.

  R Babb, M A Cleary, W Herr
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Transformed cells require continuous activity of RNA polymerase II to resist oncogene-induced apoptosis.

  C Koumenis, A Giaccia
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S.

  High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice.

  W Yan, A Z Young, V C Soares, R Kelley, R Benezra, Y Zhuang
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein.

  M You, P T Ku, R Hrdlicková, H R Bose
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression.

  D J Riley, C Y Liu, W H Lee
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice.

  N A Timchenko, T E Harris, M Wilde, T A Bilyeu, B L Burgess-Beusse, M J Finegold, G J Darlington
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase.

  J A Diehl, C J Sherr
• Journal Article | Research Support, Non-U.S. Gov't

  I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain.

  P Crépieux, H Kwon, N Leclerc, W Spencer, S Richard, R Lin, J Hiscott
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes.

  P M Sharma, K Egawa, T A Gustafson, J L Martin, J M Olefsky
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase.

  J N Davis, C O Rock, M Cheng, J B Watson, R A Ashmun, H Kirk, R J Kay, M F Roussel
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase.

  Z Wu, J Wu, E Jacinto, M Karin