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Table of Contents

May 1, 1998; Volume 18,Issue 5

Gene Expression

  • GENE EXPRESSION
    Double-Stranded RNA-Independent Dimerization of Interferon-Induced Protein Kinase PKR and Inhibition of Dimerization by the Cellular P58IPK Inhibitor
    Seng-Lai Tan, Michael J. Gale, Michael G. Katze
  • GENE EXPRESSION
    Dynamic Regulation of Copper Uptake and Detoxification Genes in Saccharomyces cerevisiae
    Maria Marjorette O. Peña, Keith A. Koch, Dennis J. Thiele
  • GENE EXPRESSION
    Association of Transcription Factor IIA with TATA Binding Protein Is Required for Transcriptional Activation of a Subset of Promoters and Cell Cycle Progression inSaccharomyces cerevisiae
    Josef Ozer, Larissa E. Lezina, Joshua Ewing, Salma Audi, Paul M. Lieberman
  • GENE EXPRESSION
    Yeast RNA Polymerase II Transcription In Vitro Is Inhibited in the Presence of Nucleotide Excision Repair: Complementation of Inhibition by Holo-TFIIH and Requirement for RAD26
    Zhaoyang You, William J. Feaver, Errol C. Friedberg
  • GENE EXPRESSION
    Ski6p Is a Homolog of RNA-Processing Enzymes That Affects Translation of Non-Poly(A) mRNAs and 60S Ribosomal Subunit Biogenesis
    Lionel Benard, Kathleen Carroll, Rosaura C. P. Valle, Reed B. Wickner
  • GENE EXPRESSION
    Dimerization by Translation Initiation Factor 2 Kinase GCN2 Is Mediated by Interactions in the C-Terminal Ribosome-Binding Region and the Protein Kinase Domain
    Hongfang Qiu, Minerva T. Garcia-Barrio, Alan G. Hinnebusch
  • GENE EXPRESSION
    Developmental Regulation of bicoid mRNA Stability Is Mediated by the First 43 Nucleotides of the 3′ Untranslated Region
    P. Surdej, M. Jacobs-Lorena
  • GENE EXPRESSION
    Selenium Deficiency Reduces the Abundance of mRNA for Se-Dependent Glutathione Peroxidase 1 by a UGA-Dependent Mechanism Likely To Be Nonsense Codon-Mediated Decay of Cytoplasmic mRNA
    Patrick M. Moriarty, C. Channa Reddy, Lynne E. Maquat

Transcriptional Regulation

  • TRANSCRIPTIONAL REGULATION
    Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit
    Tomohiko Kanno, Yuka Kanno, Lin-Feng Chen, Eiko Ogawa, Woo-Young Kim, Yoshiaki Ito
  • TRANSCRIPTIONAL REGULATION
    Chromatin Remodeling Mediated by Drosophila GAGA Factor and ISWI Activates fushi tarazu Gene Transcription In Vitro
    Masahiro Okada, Susumu Hirose
  • TRANSCRIPTIONAL REGULATION
    Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences
    Shrikesh Sachdev, Alexander Hoffmann, Mark Hannink
  • TRANSCRIPTIONAL REGULATION
    Transcriptional Activation of the Integrated Chromatin-Associated Human Immunodeficiency Virus Type 1 Promoter
    Aboubaker El Kharroubi, Graziella Piras, Ralf Zensen, Malcolm A. Martin
  • TRANSCRIPTIONAL REGULATION
    Alternative Splicing Variants of IκBβ Establish Differential NF-κB Signal Responsiveness in Human Cells
    Fuminori Hirano, Mirra Chung, Hirotoshi Tanaka, Naoki Maruyama, Isao Makino, David D. Moore, Claus Scheidereit
  • TRANSCRIPTIONAL REGULATION
    The HMG Domain Protein SSRP1/PREIIBF Is Involved in Activation of the Human Embryonic β-Like Globin Gene
    Michael A. Dyer, Patrick J. Hayes, Margaret H. Baron
  • TRANSCRIPTIONAL REGULATION
    Cooperative Pho2-Pho4 Interactions at thePHO5 Promoter Are Critical for Binding of Pho4 to UASp1 and for Efficient Transactivation by Pho4 at UASp2
    Slobodan Barbaric, Martin Münsterkötter, Colin Goding, Wolfram Hörz
  • TRANSCRIPTIONAL REGULATION
    The N-Terminal Domain of IκBα Masks the Nuclear Localization Signal(s) of p50 and c-Rel Homodimers
    Matthew Latimer, Mary K. Ernst, Linda L. Dunn, Marina Drutskaya, Nancy R. Rice
  • TRANSCRIPTIONAL REGULATION
    Two Distinct Domains in Staf To Selectively Activate Small Nuclear RNA-Type and mRNA Promoters
    Catherine Schuster, Alain Krol, Philippe Carbon
  • TRANSCRIPTIONAL REGULATION
    The Drosophila Polycomb Group Protein Psc Contacts ph and Pc through Specific Conserved Domains
    Michael Kyba, Hugh W. Brock
  • TRANSCRIPTIONAL REGULATION
    c-Maf Interacts with c-Myb To Regulate Transcription of an Early Myeloid Gene during Differentiation
    Shrikanth P. Hegde, Alok Kumar, Cornelia Kurschner, Linda H. Shapiro
  • TRANSCRIPTIONAL REGULATION
    Tumor Suppressor p53 Can Participate in Transcriptional Induction of the GADD45 Promoter in the Absence of Direct DNA Binding
    Qimin Zhan, I-Tsuen Chen, Michael J. Antinore, Albert J. Fornace
  • TRANSCRIPTIONAL REGULATION
    Two Distinct Types of Repression Domain in Engrailed: One Interacts with the Groucho Corepressor and Is Preferentially Active on Integrated Target Genes
    Elena N. Tolkunova, Miki Fujioka, Masatomo Kobayashi, Deepali Deka, James B. Jaynes
  • TRANSCRIPTIONAL REGULATION
    Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun
    Alexander Zagariya, Shubhangee Mungre, Rosa Lovis, Michael Birrer, Scott Ness, Bayar Thimmapaya, Richard Pope
  • TRANSCRIPTIONAL REGULATION
    The Drosophila esc and E(z) Proteins Are Direct Partners in Polycomb Group-Mediated Repression
    Clark A. Jones, Joyce Ng, Aidan J. Peterson, Kelly Morgan, Jeffrey Simon, Richard S. Jones
  • TRANSCRIPTIONAL REGULATION
    Interaction of Tumor Necrosis Factor Receptor-Associated Factor Signaling Proteins with the Latent Membrane Protein 1 PXQXT Motif Is Essential for Induction of Epidermal Growth Factor Receptor Expression
    William E. Miller, Jeanette L. Cheshire, Nancy Raab-Traub
  • TRANSCRIPTIONAL REGULATION
    Stepwise Recruitment of Components of the Preinitiation Complex by Upstream Activators In Vivo
    Song He, Steven Jay Weintraub
  • TRANSCRIPTIONAL REGULATION
    Distinct Functions Are Implicated for the GATA-4, -5, and -6 Transcription Factors in the Regulation of Intestine Epithelial Cell Differentiation
    Xiaoping Gao, Tiffany Sedgwick, Yun-Bo Shi, Todd Evans
  • TRANSCRIPTIONAL REGULATION
    Carbon Source-Dependent Phosphorylation of Hexokinase PII and Its Role in the Glucose-Signaling Response in Yeast
    Francisca Randez-Gil, Pascual Sanz, Karl-Dieter Entian, Jose Antonio Prieto
  • TRANSCRIPTIONAL REGULATION
    Nuclear Receptor DAX-1 Recruits Nuclear Receptor Corepressor N-CoR to Steroidogenic Factor 1
    Peter A. Crawford, Christoph Dorn, Yoel Sadovsky, Jeffrey Milbrandt
  • TRANSCRIPTIONAL REGULATION
    p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene
    Yi Qiu, Arun Sharma, Roland Stein
  • TRANSCRIPTIONAL REGULATION
    Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation
    Rongtuan Lin, Christophe Heylbroeck, Paula M. Pitha, John Hiscott
  • TRANSCRIPTIONAL REGULATION
    Induction of Sp1 in Differentiating Human Embryonal Carcinoma Cells Triggers Transcription of the Fibronectin Gene
    Mitsuhiro Suzuki, Eri Oda, Takuma Nakajima, Souei Sekiya, Kinichiro Oda

Cell Growth and Development

  • CELL GROWTH AND DEVELOPMENT
    The Gfi-1B Proto-Oncoprotein Repressesp21WAF1 and Inhibits Myeloid Cell Differentiation
    Betty Tong, H. Leighton Grimes, Tong-Yuan Yang, Susan E. Bear, Zhihai Qin, Keyong Du, Wafik S. El-Deiry, Philip N. Tsichlis
  • CELL GROWTH AND DEVELOPMENT
    Wnt-1 Induces Growth, Cytosolic β-Catenin, and Tcf/Lef Transcriptional Activation in Rat-1 Fibroblasts
    C. S. Young, Marina Kitamura, Stephen Hardy, Jan Kitajewski
  • CELL GROWTH AND DEVELOPMENT
    Activation of the Small GTPase Ral in Platelets
    Rob M. F. Wolthuis, Barbara Franke, Miranda van Triest, Bettina Bauer, Robbert H. Cool, Jacques H. Camonis, Jan-Willem N. Akkerman, Johannes L. Bos
  • CELL GROWTH AND DEVELOPMENT
    Regulation of Cell Size by Glucose Is Exerted via Repression of the CLN1 Promoter
    Karin Flick, Daphne Chapman-Shimshoni, David Stuart, Marisela Guaderrama, Curt Wittenberg
  • CELL GROWTH AND DEVELOPMENT
    Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation
    James Turkson, Tammy Bowman, Roy Garcia, Eric Caldenhoven, Rolf P. De Groot, Richard Jove
  • CELL GROWTH AND DEVELOPMENT
    Stat3 Activation Is Required for Cellular Transformation by v-src
    Jacqueline F. Bromberg, Curt M. Horvath, Daniel Besser, Wyndham W. Lathem, James E. Darnell
  • CELL GROWTH AND DEVELOPMENT
    Multiple Grb2-Mediated Integrin-Stimulated Signaling Pathways to ERK2/Mitogen-Activated Protein Kinase: Summation of Both c-Src- and Focal Adhesion Kinase-Initiated Tyrosine Phosphorylation Events
    David D. Schlaepfer, K. C. Jones, Tony Hunter
  • CELL GROWTH AND DEVELOPMENT
    Ras Signals to the Cell Cycle Machinery via Multiple Pathways To Induce Anchorage-Independent Growth
    Jaw-Ji Yang, Jong-Sun Kang, Robert S. Krauss
  • CELL GROWTH AND DEVELOPMENT
    The Second Catalytic Domain of Protein Tyrosine Phosphatase δ (PTPδ) Binds to and Inhibits the First Catalytic Domain of PTPς
    Megan J. Wallace, Christopher Fladd, Jane Batt, Daniela Rotin
  • CELL GROWTH AND DEVELOPMENT
    Increased c-fos mRNA Expression By Human Fibroblasts Contracting Stressed Collagen Matrices
    Hans Rosenfeldt, David J. Lee, Frederick Grinnell
  • CELL GROWTH AND DEVELOPMENT
    Fission Yeast rad12+Regulates Cell Cycle Checkpoint Control and Is Homologous to the Bloom’s Syndrome Disease Gene
    Scott Davey, Christine S. Han, Sarah A. Ramer, Jennifer C. Klassen, Adam Jacobson, Andrew Eisenberger, Kevin M. Hopkins, Howard B. Lieberman, Greg A. Freyer
  • CELL GROWTH AND DEVELOPMENT
    Bub1p Kinase Activates the Saccharomyces cerevisiae Spindle Assembly Checkpoint
    Katie A. Farr, M. Andrew Hoyt
  • CELL GROWTH AND DEVELOPMENT
    Negative Regulation of DNA Replication by the Retinoblastoma Protein Is Mediated by Its Association with MCM7
    Jacqueline M. Sterner, Susan Dew-Knight, Christine Musahl, Sally Kornbluth, Jonathan M. Horowitz
  • CELL GROWTH AND DEVELOPMENT
    Human CDC6/Cdc18 Associates with Orc1 and Cyclin-cdk and Is Selectively Eliminated from the Nucleus at the Onset of S Phase
    Partha Saha, Junjie Chen, Kelly C. Thome, Stephanie J. Lawlis, Zhi-hui Hou, Marvin Hendricks, Jeffrey D. Parvin, Anindya Dutta
  • CELL GROWTH AND DEVELOPMENT
    Regulation of Proliferation-Survival Decisions during Tumor Cell Hypoxia
    Cornelius Schmaltz, Patricia Harrigan Hardenbergh, Audrey Wells, David E. Fisher
  • CELL GROWTH AND DEVELOPMENT
    Genetic Evidence of a Role for Lck in T-Cell Receptor Function Independent or Downstream of ZAP-70/Syk Protein Tyrosine Kinases
    Jane Wong, David Straus, Andrew C. Chan
  • CELL GROWTH AND DEVELOPMENT
    Axil, a Member of the Axin Family, Interacts with Both Glycogen Synthase Kinase 3β and β-Catenin and Inhibits Axis Formation ofXenopus Embryos
    Hideki Yamamoto, Shosei Kishida, Takaaki Uochi, Satoshi Ikeda, Shinya Koyama, Makoto Asashima, Akira Kikuchi
  • CELL GROWTH AND DEVELOPMENT
    Ash1, a Daughter Cell-Specific Protein, Is Required for Pseudohyphal Growth of Saccharomyces cerevisiae
    Sarat Chandarlapaty, Beverly Errede
  • CELL GROWTH AND DEVELOPMENT
    Commitment and Effector Phases of the Physiological Cell Death Pathway Elucidated with Respect to Bcl-2, Caspase, and Cyclin-Dependent Kinase Activities
    Kevin J. Harvey, James F. Blomquist, David S. Ucker
  • CELL GROWTH AND DEVELOPMENT
    Molecular Evolution Allows Bypass of the Requirement for Activation Loop Phosphorylation of the Cdc28 Cyclin-Dependent Kinase
    Frederick R. Cross, Kristi Levine
  • CELL GROWTH AND DEVELOPMENT
    Protein Tyrosine Phosphatase 1B Antagonizes Signalling by Oncoprotein Tyrosine Kinase p210 bcr-abl In Vivo
    Kenneth R. LaMontagne, Andrew J. Flint, B. Robert Franza, Ann Marie Pendergast, Nicholas K. Tonks
  • CELL GROWTH AND DEVELOPMENT
    AP-1 Factors Play an Important Role in Transformation Induced by the v-rel Oncogene
    Jarmila Kralova, Andrew S. Liss, William Bargmann, Henry R. Bose
  • CELL GROWTH AND DEVELOPMENT
    Mutation in the Arabidopsis PASTICCINO1Gene, Which Encodes a New FK506-Binding Protein-Like Protein, Has a Dramatic Effect on Plant Development
    Paola Vittorioso, Rachel Cowling, Jean-Denis Faure, Michel Caboche, Catherine Bellini
  • CELL GROWTH AND DEVELOPMENT
    Activation of Rho-Dependent Cell Spreading and Focal Adhesion Biogenesis by the v-Crk Adaptor Protein
    Zeynep F. Altun-Gultekin, Sanjay Chandriani, Cecile Bougeret, Toshimasa Ishizaki, Shuh Narumiya, Petra de Graaf, Paul Van Bergen en Henegouwen, Hidesaburo Hanafusa, John A. Wagner, Raymond B. Birge
  • CELL GROWTH AND DEVELOPMENT
    Laron Dwarfism and Non-Insulin-Dependent Diabetes Mellitus in the Hnf-1α Knockout Mouse
    Ying-Hue Lee, Brian Sauer, Frank J. Gonzalez
  • CELL GROWTH AND DEVELOPMENT
    Localization of Atypical Protein Kinase C Isoforms into Lysosome-Targeted Endosomes through Interaction with p62
    Pilar Sanchez, Guillermo De Carcer, Ignacio V. Sandoval, Jorge Moscat, María T. Diaz-Meco
  • CELL GROWTH AND DEVELOPMENT
    Selective Disruption of Genes Transiently Induced in Differentiating Mouse Embryonic Stem Cells by Using Gene Trap Mutagenesis and Site-Specific Recombination
    Irmgard S. Thorey, Katrin Muth, Andreas P. Russ, Jürgen Otte, Armin Reffelmann, Harald von Melchner

Dna Dynamics and Chromosome Structure

  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    Posttranslational Regulation of Ty1 Retrotransposition by Mitogen-Activated Protein Kinase Fus3
    Darryl Conte, Ellen Barber, Mukti Banerjee, David J. Garfinkel, M. Joan Curcio
  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    Assembly of T-Antigen Double Hexamers on the Simian Virus 40 Core Origin Requires Only a Subset of the Available Binding Sites
    Woo S. Joo, Henry Y. Kim, John D. Purviance, K. R. Sreekumar, Peter A. Bullock
  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t)
    Robert J. Kokoska, Lela Stefanovic, Hiep T. Tran, Michael A. Resnick, Dmitry A. Gordenin, Thomas D. Petes
  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    Transcription-Dependent DNA Transactions in the Mitochondrial Genome of a Yeast Hypersuppressive Petite Mutant
    Eric Van Dyck, David A. Clayton
  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    A Promoter Region Mutation Affecting Replication of the Tetrahymena Ribosomal DNA Minichromosome
    Renata C. Gallagher, Elizabeth H. Blackburn
  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    Gene Amplification in a p53-Deficient Cell Line Requires Cell Cycle Progression under Conditions That Generate DNA Breakage
    Thomas G. Paulson, Alexandru Almasan, Linnea L. Brody, Geoffrey M. Wahl

Cell and Organelle Structure and Assembly

  • CELL AND ORGANELLE STRUCTURE AND ASSEMBLY
    Mutants of the Yeast Yarrowia lipolyticaDefective in Protein Exit from the Endoplasmic Reticulum Are Also Defective in Peroxisome Biogenesis
    Vladimir I. Titorenko, Richard A. Rachubinski

Errata

  • Erratum
    Mutations of the Drosophila dDP, dE2F, andcyclin E Genes Reveal Distinct Roles for the E2F-DP Transcription Factor and Cyclin E during the G1-S Transition
    Robert J. Duronio, Peter C. Bonnette, Patrick H. O’Farrell
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