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GENE EXPRESSION

Thymidylate Synthase Protein and p53 mRNA Form an In Vivo Ribonucleoprotein Complex

Edward Chu, Sitki M. Copur, Jingfang Ju, Tian-men Chen, Samir Khleif, Donna M. Voeller, Nobuyuki Mizunuma, Mahendra Patel, Gladys F. Maley, Frank Maley, Carmen J. Allegra
Edward Chu
Department of Medicine and Pharmacology, Yale Cancer Center and VA CT Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520;
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Sitki M. Copur
Medicine Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20889-5105; and
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Jingfang Ju
Department of Medicine and Pharmacology, Yale Cancer Center and VA CT Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520;
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Tian-men Chen
Department of Medicine and Pharmacology, Yale Cancer Center and VA CT Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520;
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Samir Khleif
Medicine Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20889-5105; and
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Donna M. Voeller
Medicine Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20889-5105; and
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Nobuyuki Mizunuma
Medicine Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20889-5105; and
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Mahendra Patel
Medicine Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20889-5105; and
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Gladys F. Maley
Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany, New York 12201
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Frank Maley
Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany, New York 12201
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Carmen J. Allegra
Medicine Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20889-5105; and
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DOI: 10.1128/MCB.19.2.1582
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Article Information

DOI 
https://doi.org/10.1128/MCB.19.2.1582
PubMed 
9891091

Published By 
American Society for Microbiology Journals
History 
  • Received June 15, 1998
  • Returned for modification August 18, 1998
  • Accepted October 22, 1998
  • Published online February 1, 1999.

Copyright & Usage 
Copyright © 1999 American Society for Microbiology

Author Information

  1. Edward Chu1*,
  2. Sitki M. Copur2,
  3. Jingfang Ju1,
  4. Tian-men Chen1,
  5. Samir Khleif2,
  6. Donna M. Voeller2,
  7. Nobuyuki Mizunuma2,
  8. Mahendra Patel2,
  9. Gladys F. Maley3,
  10. Frank Maley3 and
  11. Carmen J. Allegra2
  1. Department of Medicine and Pharmacology, Yale Cancer Center and VA CT Cancer Center, Yale University School of Medicine, New Haven, Connecticut 065201;
  2. Medicine Branch, Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20889-51052; and
  3. Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany, New York 122013
  • ↵* Corresponding author. Mailing address: VA CT Healthcare System, Cancer Center-111D, 950 Campbell Ave., West Haven, CT 06516. Phone: (203) 937-3421. Fax: (203) 937-3803.

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Thymidylate Synthase Protein and p53 mRNA Form an In Vivo Ribonucleoprotein Complex
Edward Chu, Sitki M. Copur, Jingfang Ju, Tian-men Chen, Samir Khleif, Donna M. Voeller, Nobuyuki Mizunuma, Mahendra Patel, Gladys F. Maley, Frank Maley, Carmen J. Allegra
Molecular and Cellular Biology Feb 1999, 19 (2) 1582-1594; DOI: 10.1128/MCB.19.2.1582

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Thymidylate Synthase Protein and p53 mRNA Form an In Vivo Ribonucleoprotein Complex
Edward Chu, Sitki M. Copur, Jingfang Ju, Tian-men Chen, Samir Khleif, Donna M. Voeller, Nobuyuki Mizunuma, Mahendra Patel, Gladys F. Maley, Frank Maley, Carmen J. Allegra
Molecular and Cellular Biology Feb 1999, 19 (2) 1582-1594; DOI: 10.1128/MCB.19.2.1582
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KEYWORDS

Genes, p53
RNA, Messenger
Ribonucleoproteins
Thymidylate Synthase

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