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GENE EXPRESSION

The Properties of a tRNA-Specific Adenosine Deaminase from Drosophila melanogaster Support an Evolutionary Link between Pre-mRNA Editing and tRNA Modification

Liam P. Keegan, André P. Gerber, Jim Brindle, Ronny Leemans, Angela Gallo, Walter Keller, Mary A. O'Connell
Liam P. Keegan
MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom,and
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André P. Gerber
Department of Cell Biology, Biozentrum of the University of Basel, CH-4056 Basel, and
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Jim Brindle
MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom,and
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Ronny Leemans
Zoological Institute, University of Basel, CH-4051 Basel, Switzerland
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Angela Gallo
MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom,and
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Walter Keller
Department of Cell Biology, Biozentrum of the University of Basel, CH-4056 Basel, and
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Mary A. O'Connell
MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom,and
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DOI: 10.1128/MCB.20.3.825-833.2000
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Article Information

DOI 
https://doi.org/10.1128/MCB.20.3.825-833.2000
PubMed 
10629039

Published By 
American Society for Microbiology Journals
History 
  • Received August 16, 1999
  • Returned for modification September 30, 1999
  • Accepted November 1, 1999
  • Published online February 1, 2000.

Copyright & Usage 
Copyright © 2000 American Society for Microbiology

Author Information

  1. Liam P. Keegan1,
  2. André P. Gerber2,
  3. Jim Brindle1,
  4. Ronny Leemans3,
  5. Angela Gallo1,
  6. Walter Keller2 and
  7. Mary A. O'Connell1*
  1. MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom,1and
  2. Department of Cell Biology, Biozentrum of the University of Basel, CH-4056 Basel,2 and
  3. Zoological Institute, University of Basel, CH-4051 Basel,3 Switzerland
  • ↵* Corresponding author. Mailing address: MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, United Kingdom. Phone: 44-131-467 8417. Fax: 44-131-343 2620. E-mail:Mary.O-Connell{at}hgu.mrc.ac.uk.

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The Properties of a tRNA-Specific Adenosine Deaminase from Drosophila melanogaster Support an Evolutionary Link between Pre-mRNA Editing and tRNA Modification
Liam P. Keegan, André P. Gerber, Jim Brindle, Ronny Leemans, Angela Gallo, Walter Keller, Mary A. O'Connell
Molecular and Cellular Biology Feb 2000, 20 (3) 825-833; DOI: 10.1128/MCB.20.3.825-833.2000

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The Properties of a tRNA-Specific Adenosine Deaminase from Drosophila melanogaster Support an Evolutionary Link between Pre-mRNA Editing and tRNA Modification
Liam P. Keegan, André P. Gerber, Jim Brindle, Ronny Leemans, Angela Gallo, Walter Keller, Mary A. O'Connell
Molecular and Cellular Biology Feb 2000, 20 (3) 825-833; DOI: 10.1128/MCB.20.3.825-833.2000
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KEYWORDS

adenosine deaminase
Drosophila melanogaster
Evolution, Molecular
Phylogeny
RNA editing
RNA Processing, Post-Transcriptional

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