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GENE EXPRESSION

Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)-Binding Protein, and Eukaryotic Translation Initiation Factor 4G

Barsanjit Mazumder, Vasudevan Seshadri, Hiroaki Imataka, Nahum Sonenberg, Paul L. Fox
Barsanjit Mazumder
Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, and
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Vasudevan Seshadri
Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, and
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Hiroaki Imataka
Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec, Canada H3G 1Y6
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Nahum Sonenberg
Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec, Canada H3G 1Y6
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Paul L. Fox
Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, and
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DOI: 10.1128/MCB.21.19.6440-6449.2001
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Article Information

DOI 
https://doi.org/10.1128/MCB.21.19.6440-6449.2001
PubMed 
11533233

Published By 
American Society for Microbiology Journals
History 
  • Received March 13, 2001
  • Returned for modification May 2, 2001
  • Accepted July 6, 2001
  • Published online October 1, 2001.

Copyright & Usage 
Copyright © 2001 American Society for Microbiology

Author Information

  1. Barsanjit Mazumder1,
  2. Vasudevan Seshadri1,
  3. Hiroaki Imataka2,
  4. Nahum Sonenberg2 and
  5. Paul L. Fox1*
  1. Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195,1 and
  2. Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec, Canada H3G 1Y62
  • ↵* Corresponding author. Mailing address: Department of Cell Biology, The Lerner Research Institute/NC10, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195. Phone: (216) 444-8053. Fax: (216) 444-9404. E-mail: foxp{at}ccf.org.

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Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)-Binding Protein, and Eukaryotic Translation Initiation Factor 4G
Barsanjit Mazumder, Vasudevan Seshadri, Hiroaki Imataka, Nahum Sonenberg, Paul L. Fox
Molecular and Cellular Biology Oct 2001, 21 (19) 6440-6449; DOI: 10.1128/MCB.21.19.6440-6449.2001

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Translational Silencing of Ceruloplasmin Requires the Essential Elements of mRNA Circularization: Poly(A) Tail, Poly(A)-Binding Protein, and Eukaryotic Translation Initiation Factor 4G
Barsanjit Mazumder, Vasudevan Seshadri, Hiroaki Imataka, Nahum Sonenberg, Paul L. Fox
Molecular and Cellular Biology Oct 2001, 21 (19) 6440-6449; DOI: 10.1128/MCB.21.19.6440-6449.2001
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KEYWORDS

Ceruloplasmin
gene silencing
Peptide Initiation Factors
Protein Biosynthesis
RNA, Messenger
RNA-binding proteins

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