Human MCF10A Mammary Epithelial Cells Undergo Apoptosis following Actin Depolymerization That Is Independent of Attachment and Rescued by Bcl-2

Stuart S. Martin; Philip Leder

doi:10.1128/MCB.21.19.6529-6536.2001

DOI: 10.1128/MCB.21.19.6529-6536.2001

Article Information

DOI

https://doi.org/10.1128/MCB.21.19.6529-6536.2001

PubMed

11533241

Published By

American Society for Microbiology Journals

History

Received March 27, 2001
Returned for modification June 11, 2001
Accepted July 2, 2001
Published online October 1, 2001.

Author Information

Stuart S. Martin and
Philip Leder*

Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115

↵* Corresponding author. Mailing address: Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, Warren Alpert Bldg., Rm 539, 200 Longwood Ave., Boston, MA 02115. Phone: (617) 432-7667. Fax: (617) 432-7944. E-mail:leder{at}rascal.med.harvard.edu.

View Abstract

Article usage

Article usage: August 2001 to January 2021

Rendering graph...

	Abstract	Full	Pdf
Aug 2001	21	4	17
Sep 2001	136	153	161
Oct 2001	18	116	73
Nov 2001	9	60	26
Dec 2001	9	54	24
Jan 2002	11	90	34
Feb 2002	6	78	22
Mar 2002	10	32	15
Apr 2002	4	36	42
May 2002	3	43	22
Jun 2002	2	39	26
Jul 2002	9	27	35
Aug 2002	1	30	26
Sep 2002	3	28	31
Oct 2002	0	21	21
Nov 2002	1	18	11
Dec 2002	2	24	19
Jan 2003	1	19	17
Feb 2003	0	20	19
Mar 2003	2	29	26
Apr 2003	3	35	31
May 2003	0	29	53
Jun 2003	4	34	25
Jul 2003	6	30	17
Aug 2003	15	44	23
Sep 2003	5	52	34
Oct 2003	12	61	43
Nov 2003	12	65	35
Dec 2003	10	46	23
Jan 2004	11	58	35
Feb 2004	12	73	32
Mar 2004	14	68	28
Apr 2004	14	60	21
May 2004	21	71	30
Jun 2004	16	49	15
Jul 2004	17	50	14
Aug 2004	17	70	47
Sep 2004	21	82	32
Oct 2004	17	81	34
Nov 2004	20	77	36
Dec 2004	21	61	26
Jan 2005	44	71	32
Feb 2005	29	56	33
Mar 2005	14	82	29
Apr 2005	25	50	12
May 2005	38	65	42
Jun 2005	48	63	43
Jul 2005	32	56	26
Aug 2005	36	67	36
Sep 2005	27	43	18
Oct 2005	28	48	31
Nov 2005	36	56	28
Dec 2005	41	41	25
Jan 2006	66	53	28
Feb 2006	50	43	20
Mar 2006	52	36	42
Apr 2006	64	48	36
May 2006	70	41	37
Jun 2006	72	51	42
Jul 2006	62	36	21
Aug 2006	63	44	28
Sep 2006	52	40	35
Oct 2006	85	39	30
Nov 2006	65	26	40
Dec 2006	55	33	21
Jan 2007	86	35	36
Feb 2007	73	25	28
Mar 2007	76	34	31
Apr 2007	97	31	33
May 2007	92	33	43
Jun 2007	119	43	33
Jul 2007	123	49	42
Aug 2007	113	38	17
Sep 2007	54	25	19
Oct 2007	81	50	34
Nov 2007	87	31	20
Dec 2007	78	37	30
Jan 2008	114	36	20
Feb 2008	142	51	26
Mar 2008	102	29	31
Apr 2008	124	50	44
May 2008	142	56	36
Jun 2008	121	41	25
Jul 2008	105	37	35
Aug 2008	106	32	30
Sep 2008	136	62	38
Oct 2008	138	61	40
Nov 2008	122	39	26
Dec 2008	93	25	22
Jan 2009	145	69	54
Feb 2009	135	50	51
Mar 2009	139	62	48
Apr 2009	174	58	44
May 2009	165	65	45
Jun 2009	155	51	56
Jul 2009	135	47	40
Aug 2009	122	59	45
Sep 2009	141	70	52
Oct 2009	167	69	55
Nov 2009	159	74	43
Dec 2009	116	51	34
Jan 2010	118	41	49
Feb 2010	119	58	52
Mar 2010	127	72	41
Apr 2010	145	78	39
May 2010	129	48	45
Jun 2010	90	64	43
Jul 2010	103	45	45
Aug 2010	63	42	31
Sep 2010	99	55	36
Oct 2010	118	56	35
Nov 2010	94	59	33
Dec 2010	93	35	28
Jan 2011	82	49	45
Feb 2011	105	71	38
Mar 2011	112	74	58
Apr 2011	155	56	39
May 2011	170	63	42
Jun 2011	163	55	28
Jul 2011	114	50	38
Aug 2011	92	55	49
Sep 2011	91	46	35
Oct 2011	101	58	31
Nov 2011	105	52	21
Dec 2011	123	30	18
Jan 2012	116	75	22
Feb 2012	93	37	34
Mar 2012	115	76	35
Apr 2012	100	66	49
May 2012	81	64	19
Jun 2012	72	20	23
Jul 2012	88	14	25
Aug 2012	70	9	10
Sep 2012	45	22	14
Oct 2012	57	16	15
Nov 2012	80	19	19
Dec 2012	67	11	10
Jan 2013	62	10	19
Feb 2013	63	12	10
Mar 2013	87	13	16
Apr 2013	58	55	21
May 2013	41	27	15
Jun 2013	54	50	11
Jul 2013	51	40	9
Aug 2013	56	23	12
Sep 2013	83	17	12
Oct 2013	114	35	28
Nov 2013	61	28	47
Dec 2013	63	22	44
Jan 2014	74	16	10
Feb 2014	67	8	11
Mar 2014	60	27	13
Apr 2014	77	30	19
May 2014	72	48	14
Jun 2014	42	29	7
Jul 2014	35	31	7
Aug 2014	13	36	6
Sep 2014	17	24	6
Oct 2014	27	14	9
Nov 2014	33	25	6
Dec 2014	21	17	2
Jan 2015	32	18	6
Feb 2015	20	29	7
Mar 2015	36	30	14
Apr 2015	14	23	4
May 2015	25	12	6
Jun 2015	18	13	7
Jul 2015	24	13	10
Aug 2015	25	16	9
Sep 2015	29	16	11
Oct 2015	12	12	6
Nov 2015	15	14	6
Dec 2015	19	21	9
Jan 2016	17	14	6
Feb 2016	13	18	8
Mar 2016	33	20	15
Apr 2016	8	18	7
May 2016	11	14	5
Jun 2016	13	7	7
Jul 2016	21	22	6
Aug 2016	15	21	6
Sep 2016	35	15	6
Oct 2016	17	14	5
Nov 2016	25	15	5
Dec 2016	26	12	3
Jan 2017	18	31	8
Feb 2017	22	28	7
Mar 2017	23	28	4
Apr 2017	12	10	2
May 2017	20	24	8
Jun 2017	11	19	6
Jul 2017	6	29	6
Aug 2017	13	27	9
Sep 2017	6	21	5
Oct 2017	11	27	5
Nov 2017	7	24	4
Dec 2017	7	19	10
Jan 2018	15	13	9
Feb 2018	9	5	4
Mar 2018	7	32	5
Apr 2018	13	36	9
May 2018	10	26	8
Jun 2018	11	18	5
Jul 2018	4	24	5
Aug 2018	3	12	4
Sep 2018	1	37	13
Oct 2018	1	23	6
Nov 2018	3	27	8
Dec 2018	2	17	3
Jan 2019	2	16	7
Feb 2019	7	15	8
Mar 2019	3	19	6
Apr 2019	3	23	3
May 2019	4	27	11
Jun 2019	2	22	11
Jul 2019	6	37	12
Aug 2019	2	32	6
Sep 2019	7	46	14
Oct 2019	4	44	30
Nov 2019	3	64	11
Dec 2019	5	60	11
Jan 2020	1	43	3
Feb 2020	3	75	11
Mar 2020	3	40	5
Apr 2020	5	50	11
May 2020	1	48	5
Jun 2020	3	72	10
Jul 2020	1	46	1
Aug 2020	2	37	17
Sep 2020	5	60	8
Oct 2020	0	45	7
Nov 2020	3	57	16
Dec 2020	4	50	6
Jan 2021	2	19	5