Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy

Markos Leggas; Masashi Adachi; George L. Scheffer; Daxi Sun; Peter Wielinga; Guoqing Du; Kelly E. Mercer; Yanli Zhuang; John C. Panetta; Brad Johnston; Rik J. Scheper; Clinton F. Stewart; John D. Schuetz

doi:10.1128/MCB.24.17.7612-7621.2004

DOI: 10.1128/MCB.24.17.7612-7621.2004

Article Information

DOI

https://doi.org/10.1128/MCB.24.17.7612-7621.2004

PubMed

15314169

Published By

American Society for Microbiology Journals

History

Received April 6, 2004
Returned for modification May 29, 2004
Accepted June 12, 2004
Published online August 16, 2004.

Author Information

Markos Leggas¹,
Masashi Adachi¹,
George L. Scheffer²,
Daxi Sun¹,
Peter Wielinga³,
Guoqing Du¹,
Kelly E. Mercer¹,
Yanli Zhuang¹,
John C. Panetta¹,
Brad Johnston¹,
Rik J. Scheper²,
Clinton F. Stewart¹ and
John D. Schuetz¹ *

¹Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee
²Department of Pathology, VU Medical Center
³Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

↵* Corresponding author. Mailing address: Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105-2794. Phone: (901) 495-2174. Fax: (901) 525-6869. E-mail: John.schuetz{at}stjude.org .

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