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CHROMOSOME STRUCTURE AND DYNAMICS

Double-Strand Break Formation by the RAG Complex at the Bcl-2 Major Breakpoint Region and at Other Non-B DNA Structures In Vitro

Sathees C. Raghavan, Patrick C. Swanson, Yunmei Ma, Michael R. Lieber
Sathees C. Raghavan
1Norris Comprehensive Cancer Center and Departments of
2Pathology
3Biochemistry & Molecular Biology
4Biological Sciences
5Molecular Microbiology & Immunology, University of Southern California Keck School of Medicine, 1441 Eastlake Ave., Los Angeles, California 90033
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Patrick C. Swanson
6Department of Medical Microbiology and Immunology, Creighton University Medical Center, 2500 California Plaza, Omaha, Nebraska 68178
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Yunmei Ma
1Norris Comprehensive Cancer Center and Departments of
2Pathology
3Biochemistry & Molecular Biology
4Biological Sciences
5Molecular Microbiology & Immunology, University of Southern California Keck School of Medicine, 1441 Eastlake Ave., Los Angeles, California 90033
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Michael R. Lieber
1Norris Comprehensive Cancer Center and Departments of
2Pathology
3Biochemistry & Molecular Biology
4Biological Sciences
5Molecular Microbiology & Immunology, University of Southern California Keck School of Medicine, 1441 Eastlake Ave., Los Angeles, California 90033
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  • For correspondence: lieber@usc.edu
DOI: 10.1128/MCB.25.14.5904-5919.2005
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Article Information

DOI 
https://doi.org/10.1128/MCB.25.14.5904-5919.2005
PubMed 
15988007

Published By 
American Society for Microbiology Journals
History 
  • Received November 22, 2004
  • Returned for modification December 30, 2004
  • Accepted April 10, 2005
  • Published online June 29, 2005.

Copyright & Usage 
Copyright © 2005 American Society for Microbiology

Author Information

  1. Sathees C. Raghavan1,2,3,4,5,
  2. Patrick C. Swanson6,
  3. Yunmei Ma1,2,3,4,5 and
  4. Michael R. Lieber1,2,3,4,5*
  1. 1Norris Comprehensive Cancer Center and Departments of
  2. 2Pathology
  3. 3Biochemistry & Molecular Biology
  4. 4Biological Sciences
  5. 5Molecular Microbiology & Immunology, University of Southern California Keck School of Medicine, 1441 Eastlake Ave., Los Angeles, California 90033
  6. 6Department of Medical Microbiology and Immunology, Creighton University Medical Center, 2500 California Plaza, Omaha, Nebraska 68178
  • ↵* Corresponding author. Mailing address: Norris Comprehensive Cancer Center, Rm. 5428, University of Southern California, 1441 Eastlake Ave., MC9176, Los Angeles, CA 90033. Phone: (323) 865-0568. Fax: (323) 865-3019. E-mail: lieber{at}usc.edu .
  • † Supplemental material for this article may be found at http://mcb.asm.org/ .

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Double-Strand Break Formation by the RAG Complex at the Bcl-2 Major Breakpoint Region and at Other Non-B DNA Structures In Vitro
Sathees C. Raghavan, Patrick C. Swanson, Yunmei Ma, Michael R. Lieber
Molecular and Cellular Biology Jun 2005, 25 (14) 5904-5919; DOI: 10.1128/MCB.25.14.5904-5919.2005

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Double-Strand Break Formation by the RAG Complex at the Bcl-2 Major Breakpoint Region and at Other Non-B DNA Structures In Vitro
Sathees C. Raghavan, Patrick C. Swanson, Yunmei Ma, Michael R. Lieber
Molecular and Cellular Biology Jun 2005, 25 (14) 5904-5919; DOI: 10.1128/MCB.25.14.5904-5919.2005
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KEYWORDS

DNA
DNA-Binding Proteins
Genes, bcl-2
Homeodomain Proteins
Lymphoma, Follicular
Translocation, Genetic

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