Molecular and Cellular Biology: 25 (9)

May 1, 2005; Volume 25,Issue 9

Gene Expression

GENE EXPRESSION
Whole-Genome Analysis Reveals a Strong Positional Bias of Conserved dMyc-Dependent E-Boxes
Toby Hulf, Paola Bellosta, Michael Furrer, Dominik Steiger, David Svensson, Andrew Barbour, Peter Gallant
GENE EXPRESSION
cis-Regulatory Logic of Short-Range Transcriptional Repression in Drosophila melanogaster
Meghana M. Kulkarni, David N. Arnosti
GENE EXPRESSION
SPBP Is a Phosphoserine-Specific Repressor of Estrogen Receptor α
Valentina Gburcik, Nathalie Bot, Marcello Maggiolini, Didier Picard
GENE EXPRESSION
Adult Stage γ-Globin Silencing Is Mediated by a Promoter Direct Repeat Element
Akane Omori, Osamu Tanabe, James Douglas Engel, Akiyoshi Fukamizu, Keiji Tanimoto
GENE EXPRESSION
Sequence-Specific DNA Binding by the αNAC Coactivator Is Required for Potentiation of c-Jun-Dependent Transcription of the Osteocalcin Gene
Omar Akhouayri, Isabelle Quélo, René St-Arnaud
GENE EXPRESSION
Interdependent Recruitment of SAGA and Srb Mediator by Transcriptional Activator Gcn4p
Hongfang Qiu, Cuihua Hu, Fan Zhang, Gwo Jiunn Hwang, Mark J. Swanson, Cheunchit Boonchird, Alan G. Hinnebusch
GENE EXPRESSION
Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development
Peili Gu, Bryan Goodwin, Arthur C.-K. Chung, Xueping Xu, David A. Wheeler, Roger R. Price, Cristin Galardi, Li Peng, Anne M. Latour, Beverly H. Koller, Jan Gossen, Steven A. Kliewer, Austin J. Cooney
GENE EXPRESSION
Identification In Vivo of Different Rate-Limiting Steps Associated with Transcriptional Activators in the Presence and Absence of a GAGA Element
Yunyuan Vivian Wang, Hongbing Tang, David S. Gilmour
GENE EXPRESSION
Inhibition of Human Chk1 Causes Increased Initiation of DNA Replication, Phosphorylation of ATR Targets, and DNA Breakage
Randi G. Syljuåsen, Claus Storgaard Sørensen, Lasse Tengbjerg Hansen, Kasper Fugger, Cecilia Lundin, Fredrik Johansson, Thomas Helleday, Maxwell Sehested, Jiri Lukas, Jiri Bartek
GENE EXPRESSION
Id2 Mediates Tumor Initiation, Proliferation, and Angiogenesis in Rb Mutant Mice
Anna Lasorella, Gerson Rothschild, Yoshifumi Yokota, Robert G. Russell, Antonio Iavarone
GENE EXPRESSION
Myocyte Enhancer Factor 2 Acetylation by p300 Enhances Its DNA Binding Activity, Transcriptional Activity, and Myogenic Differentiation
Kewei Ma, Jonathan K. L. Chan, Guang Zhu, Zhenguo Wu
GENE EXPRESSION
Human RNA Polymerase II Elongation in Slow Motion: Role of the TFIIF RAP74 α1 Helix in Nucleoside Triphosphate-Driven Translocation
Chunfen Zhang, Katie L. Zobeck, Zachary F. Burton
GENE EXPRESSION
The Mcp Element from the bithorax Complex Contains an Insulator That Is Capable of Pairwise Interactions and Can Facilitate Enhancer-Promoter Communication
Natalia Gruzdeva, Olga Kyrchanova, Alexander Parshikov, Andrey Kullyev, Pavel Georgiev
GENE EXPRESSION
Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G₂/M Promoters
Carol Imbriano, Aymone Gurtner, Fabienne Cocchiarella, Silvia Di Agostino, Valentina Basile, Monica Gostissa, Matthias Dobbelstein, Giannino Del Sal, Giulia Piaggio, Roberto Mantovani
GENE EXPRESSION
Small Interfering RNAs That Trigger Posttranscriptional Gene Silencing Are Not Required for the Histone H3 Lys9 Methylation Necessary for Transgenic Tandem Repeat Stabilization in Neurospora crassa
Agustin Chicas, Emma C. Forrest, Silvia Sepich, Carlo Cogoni, Giuseppe Macino
GENE EXPRESSION
Defining the Order in Which Nmd3p and Rpl10p Load onto Nascent 60S Ribosomal Subunits
Matthew West, John B. Hedges, Anthony Chen, Arlen W. Johnson

Chromosome Structure and Dynamics

CHROMOSOME STRUCTURE AND DYNAMICS
Recql5 and Blm RecQ DNA Helicases Have Nonredundant Roles in Suppressing Crossovers
Yiduo Hu, Xincheng Lu, Ellen Barnes, Min Yan, Hua Lou, Guangbin Luo
CHROMOSOME STRUCTURE AND DYNAMICS
Mismatch Repair Proteins Are Activators of Toxic Responses to Chromium-DNA Damage
Elizabeth Peterson-Roth, Mindy Reynolds, George Quievryn, Anatoly Zhitkovich
CHROMOSOME STRUCTURE AND DYNAMICS
The Human Stress-Activated Protein kin17 Belongs to the Multiprotein DNA Replication Complex and Associates In Vivo with Mammalian Replication Origins
Laurent Miccoli, Isabelle Frouin, Olivia Novac, Domenic Di Paola, Francis Harper, Maria Zannis-Hadjopoulos, Giovanni Maga, Denis S. F. Biard, Jaime F. Angulo

Signal Transduction

SIGNAL TRANSDUCTION
The Mechanism of Endogenous Receptor Activation Functionally Distinguishes Prototype Canonical and Noncanonical Wnts
Guizhong Liu, Anna Bafico, Stuart A. Aaronson
SIGNAL TRANSDUCTION
FAT10, a Ubiquitin-Independent Signal for Proteasomal Degradation
Mark Steffen Hipp, Birte Kalveram, Shahri Raasi, Marcus Groettrup, Gunter Schmidtke
SIGNAL TRANSDUCTION
SUMO-1 Modification of PIASy, an E3 Ligase, Is Necessary for PIASy-Dependent Activation of Tcf-4
Motomasa Ihara, Hideki Yamamoto, Akira Kikuchi
SIGNAL TRANSDUCTION
The Pleckstrin Homology Domain-Containing Protein CKIP-1 Is Involved in Regulation of Cell Morphology and the Actin Cytoskeleton and Interaction with Actin Capping Protein
David A. Canton, Mary Ellen K. Olsten, Kyoungtae Kim, Amanda Doherty-Kirby, Gilles Lajoie, John A. Cooper, David W. Litchfield
SIGNAL TRANSDUCTION
Induction of Ectopic Olfactory Structures and Bone Morphogenetic Protein Inhibition by Rossy, a Group XII Secreted Phospholipase A₂
Ignacio Muñoz-Sanjuán, Ali H. Brivanlou
SIGNAL TRANSDUCTION
Caspase-3-Dependent β-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus
Nicole Liadis, Kiichi Murakami, Mohamed Eweida, Alisha R. Elford, Laura Sheu, Herbert Y. Gaisano, Razqallah Hakem, Pamela S. Ohashi, Minna Woo
SIGNAL TRANSDUCTION
The Phosphatidylinositol 3-Phosphate Phosphatase Myotubularin- Related Protein 6 (MTMR6) Is a Negative Regulator of the Ca²⁺-Activated K⁺ Channel K_Ca3.1
Shekhar Srivastava, Zhai Li, Lin Lin, GongXin Liu, Kyung Ko, William A. Coetzee, Edward Y. Skolnik
SIGNAL TRANSDUCTION
Integrin-Linked Kinase Mediates Bone Morphogenetic Protein 7-Dependent Renal Epithelial Cell Morphogenesis
Chungyee Leung-Hagesteijn, Ming Chang Hu, Ahalya S. Mahendra, Sunny Hartwig, Henry J. Klamut, Norman D. Rosenblum, Gregory E. Hannigan
SIGNAL TRANSDUCTION
Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases
Dirk-E. Schmidt-Arras, Annette Böhmer, Boyka Markova, Chunaram Choudhary, Hubert Serve, Frank-D. Böhmer
SIGNAL TRANSDUCTION
Caspase-Dependent Regulation and Subcellular Redistribution of the Transcriptional Modulator YY1 during Apoptosis
Anja Krippner-Heidenreich, Gesa Walsemann, Maroun J. Beyrouthy, Stefanie Speckgens, Regine Kraft, Hubert Thole, Robert V. Talanian, Myra M. Hurt, Bernhard Lüscher
SIGNAL TRANSDUCTION
Interaction of BAG1 and Hsp70 Mediates Neuroprotectivity and Increases Chaperone Activity
Jan Liman, Sundar Ganesan, Christoph P. Dohm, Stan Krajewski, John C. Reed, Mathias Bähr, Fred S. Wouters, Pawel Kermer
SIGNAL TRANSDUCTION
p21-Activated Kinase 1 Regulates Microtubule Dynamics by Phosphorylating Tubulin Cofactor B
Ratna K. Vadlamudi, Christopher J. Barnes, Suresh Rayala, Feng Li, Seetharaman Balasenthil, Stevan Marcus, Holly V. Goodson, Aysegul A. Sahin, Rakesh Kumar
SIGNAL TRANSDUCTION
Cyclins D2 and D1 Are Essential for Postnatal Pancreatic β-Cell Growth
Jake A. Kushner, Maria A. Ciemerych, Ewa Sicinska, Lynn M. Wartschow, Monica Teta, Simon Y. Long, Piotr Sicinski, Morris F. White
SIGNAL TRANSDUCTION
Interaction of Paxillin with Poly(A)-Binding Protein 1 and Its Role in Focal Adhesion Turnover and Cell Migration
Alison J. Woods, Theodoros Kantidakis, Hisataka Sabe, David R. Critchley, Jim C. Norman
SIGNAL TRANSDUCTION
Selective Regulation of c-jun Gene Expression by Mitogen-Activated Protein Kinases via the 12-O-Tetradecanoylphorbol-13-Acetate- Responsive Element and Myocyte Enhancer Factor 2 Binding Sites
Midori Kayahara, Xin Wang, Cathy Tournier
SIGNAL TRANSDUCTION
Dok-R Mediates Attenuation of Epidermal Growth Factor-Dependent Mitogen-Activated Protein Kinase and Akt Activation through Processive Recruitment of c-Src and Csk
Paul Van Slyke, Mariano Loza Coll, Zubin Master, Harold Kim, Jorge Filmus, Daniel J. Dumont
SIGNAL TRANSDUCTION
Proteasomal ATPase-Associated Factor 1 Negatively Regulates Proteasome Activity by Interacting with Proteasomal ATPases
Yoon Park, Yong-Pil Hwang, Jong-Sik Lee, Sang-Hyun Seo, Sungjoo Kim Yoon, Jong-Bok Yoon

Mammalian Genetic Models With Minimal Or Complex Phenotypes

MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
Inactivation of CtIP Leads to Early Embryonic Lethality Mediated by G₁ Restraint and to Tumorigenesis by Haploid Insufficiency
Phang-Lang Chen, Feng Liu, Suna Cai, Xiaoqin Lin, Aihua Li, Yumay Chen, Bingnan Gu, Eva Y.-H. P. Lee, Wen-Hwa Lee
MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
Targeted Disruption of Tgif, the Mouse Ortholog of a Human Holoprosencephaly Gene, Does Not Result in Holoprosencephaly in Mice
Jun Shen, Christopher A. Walsh
MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
The Distal Sequence Element of the Selenocysteine tRNA Gene Is a Tissue-Dependent Enhancer Essential for Mouse Embryogenesis
Vincent P. Kelly, Takafumi Suzuki, Osamu Nakajima, Tsuyoshi Arai, Yoshitaka Tamai, Satoru Takahashi, Susumu Nishimura, Masayuki Yamamoto
MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
Role of MLK3 in the Regulation of Mitogen-Activated Protein Kinase Signaling Cascades
Deborah Brancho, Juan-Jose Ventura, Anja Jaeschke, Beth Doran, Richard A. Flavell, Roger J. Davis

Intracellular Trafficking

INTRACELLULAR TRAFFICKING
An Evolutionarily Conserved Coiled-Coil Protein Implicated in Polycystic Kidney Disease Is Involved in Basal Body Duplication and Flagellar Biogenesis in Trypanosoma brucei
Gareth W. Morgan, Paul W. Denny, Sue Vaughan, David Goulding, Tim R. Jeffries, Deborah F. Smith, Keith Gull, Mark C. Field

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Table of Contents

Gene Expression

Chromosome Structure and Dynamics

Signal Transduction

Mammalian Genetic Models With Minimal Or Complex Phenotypes

Intracellular Trafficking

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