Table of Contents

Articles

• Articles

  Reconstitution of the Reelin Signaling Pathway in Fibroblasts Demonstrates that Dab1 Phosphorylation Is Independent of Receptor Localization in Lipid Rafts

  Harald Mayer, Sarah Duit, Christoph Hauser, Wolfgang J. Schneider, Johannes Nimpf
• Articles

  Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival following DNA Damage

  Jonathan M. Solomon, Rao Pasupuleti, Lei Xu, Thomas McDonagh, Rory Curtis, Peter S. DiStefano, L. Julie Huber
• Articles

  Recruitment of DNA Damage Checkpoint Proteins to Damage in Transcribed and Nontranscribed Sequences

  Guochun Jiang, Aziz Sancar
• Articles

  Transactivation of Platelet-Derived Growth Factor Receptor α by the GTPase-Deficient Activated Mutant of Gα₁₂

  Rashmi N. Kumar, Ji Hee Ha, Rangasudhagar Radhakrishnan, Danny N. Dhanasekaran
• Articles

  Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation

  Alexandros Tzatsos, Konstantin V. Kandror
• Articles

  Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65

  Elizabeth M. Morin-Kensicki, Brian N. Boone, Michael Howell, Jaclyn R. Stonebraker, Jeremy Teed, James G. Alb, Terry R. Magnuson, Wanda O'Neal, Sharon L. Milgram
• Articles

  Distinct Roles of Phosphoinositide-3 Kinase and Phospholipase Cγ2 in B-Cell Receptor-Mediated Signal Transduction

  Xuezhi Dai, Yuhong Chen, James Schuman, Zichun Hua, John W. Adamson, Renren Wen, Demin Wang
• Articles

  Distinct Utilization of Effectors and Biological Outcomes Resulting from Site-Specific Ras Activation: Ras Functions in Lipid Rafts and Golgi Complex Are Dispensable for Proliferation and Transformation

  David Matallanas, Victoria Sanz-Moreno, Imanol Arozarena, Fernando Calvo, Lorena Agudo-Ibáñez, Eugenio Santos, María T. Berciano, Piero Crespo
• Articles

  PTF1 Is an Organ-Specific and Notch-Independent Basic Helix-Loop-Helix Complex Containing the Mammalian Suppressor of Hairless (RBP-J) or Its Paralogue, RBP-L

  Thomas M. Beres, Toshihiko Masui, Galvin H. Swift, Ling Shi, R. Michael Henke, Raymond J. MacDonald
• Articles

  Alternative Pathways for the Repair of RAG-Induced DNA Breaks

  David M. Weinstock, Maria Jasin
• Articles

  Nox2 and Rac1 Regulate H₂O₂-Dependent Recruitment of TRAF6 to Endosomal Interleukin-1 Receptor Complexes

  Qiang Li, Maged M. Harraz, Weihong Zhou, Liang N. Zhang, Wei Ding, Yulong Zhang, Tim Eggleston, Charles Yeaman, Botond Banfi, John F. Engelhardt
• Articles

  The Forkhead Transcription Factor FoxI1 Remains Bound to Condensed Mitotic Chromosomes and Stably Remodels Chromatin Structure

  Jizhou Yan, Lisha Xu, Gregory Crawford, Zenfeng Wang, Shawn M. Burgess
• Articles

  A Family of Human Zinc Finger Proteins That Bind Methylated DNA and Repress Transcription

  Guillaume J. P. Filion, Svetlana Zhenilo, Sergey Salozhin, Daisuke Yamada, Egor Prokhortchouk, Pierre-Antoine Defossez
• Articles

  Mice with a Targeted Disruption of the Cl⁻/HCO₃⁻ Exchanger AE3 Display a Reduced Seizure Threshold

  Moritz Hentschke, Martin Wiemann, Suna Hentschke, Ingo Kurth, Irm Hermans-Borgmeyer, Thomas Seidenbecher, Thomas J. Jentsch, Andreas Gal, Christian A. Hübner
• Articles

  Tissue-Specific Differences of p53 Inhibition by Mdm2 and Mdm4

  Jason D. Grier, Shunbin Xiong, Ana C. Elizondo-Fraire, John M. Parant, Guillermina Lozano
• Articles

  Kaiso-Deficient Mice Show Resistance to Intestinal Cancer

  Anna Prokhortchouk, Owen Sansom, Jim Selfridge, Isabel M. Caballero, Sergey Salozhin, Dana Aithozhina, Leandro Cerchietti, Fan Guo Meng, Leonard H. Augenlicht, John M. Mariadason, Brian Hendrich, Ari Melnick, Egor Prokhortchouk, Alan Clarke, Adrian Bird
• Articles

  Notch Activation Is an Early and Critical Event during T-Cell Leukemogenesis in Ikaros-Deficient Mice

  Alexis Dumortier, Robin Jeannet, Peggy Kirstetter, Eva Kleinmann, MacLean Sellars, Nuno R. dos Santos, Christelle Thibault, Jochen Barths, Jacques Ghysdael, Jennifer A. Punt, Philippe Kastner, Susan Chan
• Articles

  Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap1

  Akira Kobayashi, Moon-Il Kang, Yoriko Watai, Kit I. Tong, Takahiro Shibata, Koji Uchida, Masayuki Yamamoto
• Articles

  Mitogen-Activated Protein Kinase Cascade-Mediated Histone H3 Phosphorylation Is Critical for Telomerase Reverse Transcriptase Expression/Telomerase Activation Induced by Proliferation

  Zheng Ge, Cheng Liu, Magnus Björkholm, Astrid Gruber, Dawei Xu
• Articles

  Procollagen C Proteinase Enhancer 1 Genes Are Important Determinants of the Mechanical Properties and Geometry of Bone and the Ultrastructure of Connective Tissues

  Barry M. Steiglitz, Jaclynn M. Kreider, Elizabeth P. Frankenburg, William N. Pappano, Guy G. Hoffman, Jeffrey A. Meganck, Xiaowen Liang, Magnus Höök, David E. Birk, Steven A. Goldstein, Daniel S. Greenspan
• Articles

  Drosophila Paf1 Modulates Chromatin Structure at Actively Transcribed Genes

  Karen Adelman, Wenxiang Wei, M. Behfar Ardehali, Janis Werner, Bing Zhu, Danny Reinberg, John T. Lis
• Articles

  Focal Adhesion Kinase Is a Substrate and Downstream Effector of SHP-2 Complexed with Helicobacter pylori CagA

  Ryouhei Tsutsumi, Atsushi Takahashi, Takeshi Azuma, Hideaki Higashi, Masanori Hatakeyama
• Articles

  Akt-Mediated YB-1 Phosphorylation Activates Translation of Silent mRNA Species

  Valentina Evdokimova, Peter Ruzanov, Michael S. Anglesio, Alexey V. Sorokin, Lev P. Ovchinnikov, Jonathan Buckley, Timothy J. Triche, Nahum Sonenberg, Poul H. B. Sorensen
• Articles

  Innate Immune Responses in NF-κB-Repressing Factor-Deficient Mice

  Natali Froese, Michael Schwarzer, Ina Niedick, Ursula Frischmann, Mario Köster, Andrea Kröger, Peter P. Mueller, Mahtab Nourbakhsh, Bastian Pasche, Jörg Reimann, Peter Staeheli, Hansjörg Hauser
• Articles

  Direct Interaction with Rab11a Targets the Epithelial Ca²⁺ Channels TRPV5 and TRPV6 to the Plasma Membrane

  Stan F. J. van de Graaf, Qing Chang, Arjen R. Mensenkamp, Joost G. J. Hoenderop, René J. M. Bindels
• Articles

  Identifying Optimal Lipid Raft Characteristics Required To Promote Nanoscale Protein-Protein Interactions on the Plasma Membrane

  Dan V. Nicolau, Kevin Burrage, Robert G. Parton, John F. Hancock
• Articles

  Exploring the Cellular Activity of Camptothecin-Triple-Helix-Forming Oligonucleotide Conjugates

  Paola B. Arimondo, Craig J. Thomas, Kahina Oussedik, Brigitte Baldeyrou, Christine Mahieu, Ludovic Halby, Dominique Guianvarc'h, Amélie Lansiaux, Sidney M. Hecht, Christian Bailly, Carine Giovannangeli
• Articles

  Central Role for Protein Targeting to Glycogen in the Maintenance of Cellular Glycogen Stores in 3T3-L1 Adipocytes

  Cynthia C. Greenberg, Arpad M. Danos, Matthew J. Brady
• Articles

  Rhp51-Dependent Recombination Intermediates That Do Not Generate Checkpoint Signal Are Accumulated in Schizosaccharomyces pombe rad60 and smc5/6 Mutants after Release from Replication Arrest

  Izumi Miyabe, Takashi Morishita, Takashi Hishida, Shuji Yonei, Hideo Shinagawa
• Articles

  Deletion of the Gene Encoding Proprotein Convertase 5/6 Causes Early Embryonic Lethality in the Mouse

  Rachid Essalmani, Josée Hamelin, Jadwiga Marcinkiewicz, Ann Chamberland, Majambu Mbikay, Michel Chrétien, Nabil G. Seidah, Annik Prat
• Articles

  Regulation of CD44 Alternative Splicing by SRm160 and Its Potential Role in Tumor Cell Invasion

  Chonghui Cheng, Phillip A. Sharp
• Articles

  The Short-Lived Matα2 Transcriptional Repressor Is Protected from Degradation In Vivo by Interactions with Its Corepressors Tup1 and Ssn6

  Jeffrey D. Laney, Erika F. Mobley, Mark Hochstrasser
• Articles

  Replication past a trans-4-Hydroxynonenal Minor-Groove Adduct by the Sequential Action of Human DNA Polymerases ι and κ

  William T. Wolfle, Robert E. Johnson, Irina G. Minko, R. Stephen Lloyd, Satya Prakash, Louise Prakash