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Articles

The DNA Binding and Catalytic Domains of Poly(ADP-Ribose) Polymerase 1 Cooperate in the Regulation of Chromatin Structure and Transcription

David A. Wacker, Donald D. Ruhl, Ehsan H. Balagamwala, Kristine M. Hope, Tong Zhang, W. Lee Kraus
David A. Wacker
1Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
2Graduate Field of Biophysics, Cornell University, Ithaca, New York 14853
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Donald D. Ruhl
1Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
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Ehsan H. Balagamwala
1Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
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Kristine M. Hope
1Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
3Graduate Field of Environmental Toxicology, Cornell University, Ithaca, New York 14853
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Tong Zhang
1Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
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W. Lee Kraus
1Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
3Graduate Field of Environmental Toxicology, Cornell University, Ithaca, New York 14853
4Department of Pharmacology, Weill Medical College of Cornell University, New York, New York 10021
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  • For correspondence: wlk5@cornell.edu
DOI: 10.1128/MCB.01314-07
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Article Information

DOI 
https://doi.org/10.1128/MCB.01314-07
PubMed 
17785446

Published By 
American Society for Microbiology Journals
History 
  • Received July 21, 2007
  • Accepted August 16, 2007
  • Published online October 16, 2007.

Copyright & Usage 
Copyright © 2007 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (September 04, 2007).
  • You are viewing the most recent version of this article.

Author Information

  1. David A. Wacker1,2†‡,
  2. Donald D. Ruhl1‡,
  3. Ehsan H. Balagamwala1,
  4. Kristine M. Hope1,3,
  5. Tong Zhang1 and
  6. W. Lee Kraus1,3,4*
  1. 1Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
  2. 2Graduate Field of Biophysics, Cornell University, Ithaca, New York 14853
  3. 3Graduate Field of Environmental Toxicology, Cornell University, Ithaca, New York 14853
  4. 4Department of Pharmacology, Weill Medical College of Cornell University, New York, New York 10021
  • ↵‡ D.A.W. and D.D.R. contributed equally to this work.

  • ↵* Corresponding author. Mailing address: Department of Molecular Biology and Genetics, Cornell University, 465 Biotechnology Building, Ithaca, NY 14853. Phone: (607) 255-6087. Fax: (607) 255-6249. E-mail: wlk5{at}cornell.edu
  • ↵† Present address: School of Medicine, Yale University, New Haven, CT 06510.

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The DNA Binding and Catalytic Domains of Poly(ADP-Ribose) Polymerase 1 Cooperate in the Regulation of Chromatin Structure and Transcription
David A. Wacker, Donald D. Ruhl, Ehsan H. Balagamwala, Kristine M. Hope, Tong Zhang, W. Lee Kraus
Molecular and Cellular Biology Oct 2007, 27 (21) 7475-7485; DOI: 10.1128/MCB.01314-07

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The DNA Binding and Catalytic Domains of Poly(ADP-Ribose) Polymerase 1 Cooperate in the Regulation of Chromatin Structure and Transcription
David A. Wacker, Donald D. Ruhl, Ehsan H. Balagamwala, Kristine M. Hope, Tong Zhang, W. Lee Kraus
Molecular and Cellular Biology Oct 2007, 27 (21) 7475-7485; DOI: 10.1128/MCB.01314-07
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KEYWORDS

Catalytic Domain
chromatin
DNA
Poly(ADP-ribose) Polymerases
Transcription, Genetic

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