Table of Contents

Articles

• Articles

  A Novel Mechanism for the Control of Translation Initiation by Amino Acids, Mediated by Phosphorylation of Eukaryotic Initiation Factor 2B

  Xuemin Wang, Christopher G. Proud
• Articles

  Recombination-Based Telomere Maintenance Is Dependent on Tel1-MRN and Rap1 and Inhibited by Telomerase, Taz1, and Ku in Fission Yeast

  Lakxmi Subramanian, Bettina A. Moser, Toru M. Nakamura
• Articles

  Basic Helix-Loop-Helix Transcription Factors Cooperate To Specify a Cortical Projection Neuron Identity

  Pierre Mattar, Lisa Marie Langevin, Kathryn Markham, Natalia Klenin, Salma Shivji, Dawn Zinyk, Carol Schuurmans
• Articles

  DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair

  Jillian L. Youds, Louise J. Barber, Jordan D. Ward, Spencer J. Collis, Nigel J. O'Neil, Simon J. Boulton, Ann M. Rose
• Articles

  Gα₁₂/Gα₁₃ Deficiency Causes Localized Overmigration of Neurons in the Developing Cerebral and Cerebellar Cortices

  Alexandra Moers, Alexander Nürnberg, Sandra Goebbels, Nina Wettschureck, Stefan Offermanns
• Articles

  Development of Hepatocellular Carcinoma in Iqgap2-Deficient Mice Is IQGAP1 Dependent

  Valentina A. Schmidt, Carmine S. Chiariello, Encarnación Capilla, Frederick Miller, Wadie F. Bahou
• Articles

  ARS2 Is a Conserved Eukaryotic Gene Essential for Early Mammalian Development

  Michael D. Wilson, Diana Wang, Rebecca Wagner, Hilde Breyssens, Marina Gertsenstein, Corrinne Lobe, Xin Lu, Andras Nagy, Robert D. Burke, Ben F. Koop, Perry L. Howard
• Articles

  The Wnt Pool of Glycogen Synthase Kinase 3β Is Critical for Trophic-Deprivation-Induced Neuronal Death

  Vesa Hongisto, Jenni C. Vainio, Róisín Thompson, Michael J. Courtney, Eleanor T. Coffey
• Articles

  Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis

  Maria Escrivà, Sandra Peiró, Nicolás Herranz, Patricia Villagrasa, Natàlia Dave, Bàrbara Montserrat-Sentís, Stephen A. Murray, Clara Francí, Thomas Gridley, Ismo Virtanen, Antonio García de Herreros
• Articles

  CARD6 Is Interferon Inducible but Not Involved in Nucleotide-Binding Oligomerization Domain Protein Signaling Leading to NF-κB Activation

  Almut Dufner, Gordon S. Duncan, Andrew Wakeham, Alisha R. Elford, Håkan T. Hall, Pamela S. Ohashi, Tak W. Mak
• Articles

  An Evolutionarily Conserved Nuclear Export Signal Facilitates Cytoplasmic Localization of the Tbx5 Transcription Factor

  Andre Kulisz, Hans-Georg Simon
• Articles

  Sizn1 Is a Novel Protein That Functions as a Transcriptional Coactivator of Bone Morphogenic Protein Signaling

  Ginam Cho, Youngshin Lim, Dina Zand, Jeffrey A. Golden
• Articles

  Integration of Transforming Growth Factor β and RAS Signaling Silences a RAB5 Guanine Nucleotide Exchange Factor and Enhances Growth Factor-Directed Cell Migration

  Hailiang Hu, Marc Milstein, Joanne M. Bliss, Minh Thai, Gautam Malhotra, Lucia C. Huynh, John Colicelli
• Articles

  Corepressor CtBP and Nuclear Speckle Protein Pnn/DRS Differentially Modulate Transcription and Splicing of the E-Cadherin Gene

  Roman Alpatov, Yujiang Shi, Gustavo C. Munguba, Babak Moghimi, Jeong-Hoon Joo, Jorg Bungert, Stephen P. Sugrue
• Articles

  Two RNA Polymerase I Subunits Control the Binding and Release of Rrn3 during Transcription

  Frédéric Beckouet, Sylvie Labarre-Mariotte, Benjamin Albert, Yukiko Imazawa, Michel Werner, Olivier Gadal, Yasuhisa Nogi, Pierre Thuriaux
• Articles

  Deubiquitylating Enzyme UBP64 Controls Cell Fate through Stabilization of the Transcriptional Repressor Tramtrack

  Prashanth Kumar Bajpe, Jan A. van der Knaap, Jeroen A. A. Demmers, Karel Bezstarosti, Andrew Bassett, Heleen M. M. van Beusekom, Andrew A. Travers, C. Peter Verrijzer
• Articles

  Myocyte Enhancer Factor 2 and Chorion Factor 2 Collaborate in Activation of the Myogenic Program in Drosophila

  Kathleen K. Kelly Tanaka, Anton L. Bryantsev, Richard M. Cripps
• Articles

  Up-Regulation of P-TEFb by the MEK1-Extracellular Signal-Regulated Kinase Signaling Pathway Contributes to Stimulated Transcription Elongation of Immediate Early Genes in Neuroendocrine Cells

  Toshitsugu Fujita, Stephan Ryser, Isabelle Piuz, Werner Schlegel
• Articles

  Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP) Response Element Binding Protein (CREB) and cAMP-Responsive CREB Coactivator 2

  Su-Jin Kim, Cuilan Nian, Scott Widenmaier, Christopher H. S. McIntosh
• Articles

  Contribution of Annexin 2 to the Architecture of Mature Endothelial Adherens Junctions

  Stéphanie Heyraud, Michel Jaquinod, Claire Durmort, Emilie Dambroise, Evelyne Concord, Jean Patrick Schaal, Philippe Huber, Danielle Gulino-Debrac
• Articles

  Early Embryonic Lethality of Mice Lacking ZO-2, but Not ZO-3, Reveals Critical and Nonredundant Roles for Individual Zonula Occludens Proteins in Mammalian Development

  Jianliang Xu, P. Jaya Kausalya, Dominic C. Y. Phua, Safiah Mohamed Ali, Zakir Hossain, Walter Hunziker
• Articles

  Protein Kinase A-Dependent Phosphorylation Modulates β₁Pix Guanine Nucleotide Exchange Factor Activity through 14-3-3β Binding

  Ahmed Chahdi, Andrey Sorokin
• Articles

  Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

  Yu Zhang, SoHee Kwon, Teppei Yamaguchi, Fabien Cubizolles, Sophie Rousseaux, Michaela Kneissel, Chun Cao, Na Li, Hwei-Ling Cheng, Katrin Chua, David Lombard, Adam Mizeracki, Gabriele Matthias, Frederick W. Alt, Saadi Khochbin, Patrick Matthias
• Articles

  Mosaic Complementation Demonstrates a Regulatory Role for Myosin VIIa in Actin Dynamics of Stereocilia

  Haydn M. Prosser, Agnieszka K. Rzadzinska, Karen P. Steel, Allan Bradley
• Articles

  β-Catenin Expression Results in p53-Independent DNA Damage and Oncogene-Induced Senescence in Prelymphomagenic Thymocytes In Vivo

  Mai Xu, Qing Yu, Ramesh Subrahmanyam, Michael J. Difilippantonio, Thomas Ried, Jyoti Misra Sen
• Articles

  Minichromosome Maintenance Proteins Interact with Checkpoint and Recombination Proteins To Promote S-Phase Genome Stability

  Julie M. Bailis, Douglas D. Luche, Tony Hunter, Susan L. Forsburg
• Articles

  Histone H3 Tails Containing Dimethylated Lysine and Adjacent Phosphorylated Serine Modifications Adopt a Specific Conformation during Mitosis and Meiosis

  Adrien Eberlin, Cédric Grauffel, Mustapha Oulad-Abdelghani, Flavie Robert, Maria-Elena Torres-Padilla, Romain Lambrot, Danièle Spehner, Lourdes Ponce-Perez, Jean-Marie Würtz, Roland H. Stote, Sarah Kimmins, Patrick Schultz, Annick Dejaegere, Laszlo Tora
• Articles

  Centrin 2 Localizes to the Vertebrate Nuclear Pore and Plays a Role in mRNA and Protein Export

  Karen K. Resendes, Beth A. Rasala, Douglass J. Forbes
• Articles

  Peroxisome Proliferator-Activated Receptor γ Is a Target of Progesterone Regulation in the Preovulatory Follicles and Controls Ovulation in Mice

  Jaeyeon Kim, Marcey Sato, Quanxi Li, John P. Lydon, Francesco J. DeMayo, Indrani C. Bagchi, Milan K. Bagchi
• Articles

  Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL-1 Receptor-Associated Kinase 1 To Facilitate NEMO Binding and the Activation of IκBα Kinase

  Mark Windheim, Margaret Stafford, Mark Peggie, Philip Cohen
• Articles

  Jak2 FERM Domain Interaction with the Erythropoietin Receptor Regulates Jak2 Kinase Activity

  Megumi Funakoshi-Tago, Stéphane Pelletier, Hiroshi Moritake, Evan Parganas, James N. Ihle
• Articles

  The Atypical Rho GTPase Wrch1 Collaborates with the Nonreceptor Tyrosine Kinases Pyk2 and Src in Regulating Cytoskeletal Dynamics

  Aino Ruusala, Pontus Aspenström
• Articles

  Wingless Signaling Induces Widespread Chromatin Remodeling of Target Loci

  David S. Parker, Yunyun Y. Ni, Jinhee L. Chang, Jiong Li, Ken M. Cadigan
• Articles

  Centrin/Cdc31 Is a Novel Regulator of Protein Degradation

  Li Chen, Kiran Madura
• Articles

  ATP Binding by Monarch-1/NLRP12 Is Critical for Its Inhibitory Function

  Zhengmao Ye, John D. Lich, Chris B. Moore, Joseph A. Duncan, Kristi L. Williams, Jenny P.-Y. Ting
• Articles

  Mitochondrial Iba57p Is Required for Fe/S Cluster Formation on Aconitase and Activation of Radical SAM Enzymes

  Cristy Gelling, Ian W. Dawes, Nadine Richhardt, Roland Lill, Ulrich Mühlenhoff
• Articles

  Role of hPHF1 in H3K27 Methylation and Hox Gene Silencing

  Ru Cao, Hengbin Wang, Jin He, Hediye Erdjument-Bromage, Paul Tempst, Yi Zhang