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Articles

Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G2/M Checkpoint Arrest

Atsushi Shibata, Olivia Barton, Angela T. Noon, Kirsten Dahm, Dorothee Deckbar, Aaron A. Goodarzi, Markus Löbrich, Penny A. Jeggo
Atsushi Shibata
1Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, United Kingdom
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Olivia Barton
2Darmstadt University of Technology, Radiation Biology and DNA Repair, 64287 Darmstadt, Germany
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Angela T. Noon
1Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, United Kingdom
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Kirsten Dahm
1Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, United Kingdom
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Dorothee Deckbar
2Darmstadt University of Technology, Radiation Biology and DNA Repair, 64287 Darmstadt, Germany
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Aaron A. Goodarzi
1Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, United Kingdom
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Markus Löbrich
2Darmstadt University of Technology, Radiation Biology and DNA Repair, 64287 Darmstadt, Germany
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  • For correspondence: p.a.jeggo@sussex.ac.uk lobrich@bio.tu-darmstadt.de
Penny A. Jeggo
1Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, United Kingdom
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  • For correspondence: p.a.jeggo@sussex.ac.uk lobrich@bio.tu-darmstadt.de
DOI: 10.1128/MCB.01644-09
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Article Information

DOI 
https://doi.org/10.1128/MCB.01644-09
PubMed 
20421415

Published By 
American Society for Microbiology Journals
History 
  • Received December 22, 2009
  • Returned for modification January 12, 2010
  • Accepted April 16, 2010
  • Published online June 10, 2010.

Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (April 26, 2010).
  • You are viewing the most recent version of this article.

Author Information

  1. Atsushi Shibata1,
  2. Olivia Barton2,
  3. Angela T. Noon1,
  4. Kirsten Dahm1,
  5. Dorothee Deckbar2,
  6. Aaron A. Goodarzi1,
  7. Markus Löbrich2* and
  8. Penny A. Jeggo1*
  1. 1Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, United Kingdom
  2. 2Darmstadt University of Technology, Radiation Biology and DNA Repair, 64287 Darmstadt, Germany
  • ↵* Corresponding author. Mailing address for Penny A. Jeggo: Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, United Kingdom. Phone: 0044 1273 678482. Fax: 0044 1273 678121. E-mail: p.a.jeggo{at}sussex.ac.uk . Mailing address for Markus Löbrich: Darmstadt University of Technology, Radiation Biology and DNA Repair, 64287 Darmstadt, Germany. Phone: 0049 6151 167460. Fax: 0049 6151 167462. E-mail: lobrich{at}bio.tu-darmstadt.de
  • † Supplemental material for this article may be found at http://mcb.asm.org/ .

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Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G2/M Checkpoint Arrest
Atsushi Shibata, Olivia Barton, Angela T. Noon, Kirsten Dahm, Dorothee Deckbar, Aaron A. Goodarzi, Markus Löbrich, Penny A. Jeggo
Molecular and Cellular Biology Jun 2010, 30 (13) 3371-3383; DOI: 10.1128/MCB.01644-09

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Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G2/M Checkpoint Arrest
Atsushi Shibata, Olivia Barton, Angela T. Noon, Kirsten Dahm, Dorothee Deckbar, Aaron A. Goodarzi, Markus Löbrich, Penny A. Jeggo
Molecular and Cellular Biology Jun 2010, 30 (13) 3371-3383; DOI: 10.1128/MCB.01644-09
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KEYWORDS

Cell Cycle Proteins
cell division
DNA damage
DNA repair
DNA-Binding Proteins
G2 Phase
Intracellular Signaling Peptides and Proteins
Protein-Serine-Threonine Kinases
Tumor Suppressor Proteins

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