Table of Contents

September 1, 2010; Volume 30,Issue 17

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Articles of Significant Interest Selected from This Issue by the Editors

Articles

Articles
Myristoylation and Membrane Binding Regulate c-Src Stability and Kinase Activity
Parag Patwardhan, Marilyn D. Resh
Articles
A Flexible RNA Backbone within the Polypyrimidine Tract Is Required for U2AF⁶⁵ Binding and Pre-mRNA Splicing InVivo
Chun Chen, Xinliang Zhao, Ryszard Kierzek, Yi-Tao Yu
Articles
The CRL4^Cdt2 Ubiquitin Ligase Mediates the Proteolysis of Cyclin-Dependent Kinase Inhibitor Xic1 through a Direct Association with PCNA
Dong Hyun Kim, Varija N. Budhavarapu, Carlos R. Herrera, Hyung Wook Nam, Yu Sam Kim, P. Renee Yew
Articles
Myocardin-Related Transcription Factor A Is a Common Mediator of Mechanical Stress- and Neurohumoral Stimulation-Induced Cardiac Hypertrophic Signaling Leading to Activation of Brain Natriuretic Peptide Gene Expression
Koichiro Kuwahara, Hideyuki Kinoshita, Yoshihiro Kuwabara, Yasuaki Nakagawa, Satoru Usami, Takeya Minami, Yuko Yamada, Masataka Fujiwara, Kazuwa Nakao
Articles | Spotlight
Ikaros and Aiolos Inhibit Pre-B-Cell Proliferation by Directly Suppressing c-Myc Expression
Shibin Ma, Simanta Pathak, Malay Mandal, Long Trinh, Marcus R. Clark, Runqing Lu
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Opposing Roles of Dnmt1 in Early- and Late-Stage Murine Prostate Cancer
Shannon R. Morey Kinney, Michael T. Moser, Marien Pascual, John M. Greally, Barbara A. Foster, Adam R. Karpf
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Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor β Heterodimer
Jakob Vejby Larsen, Maria Hansen, Bjarne Møller, Peder Madsen, Jürgen Scheller, Morten Nielsen, Claus Munck Petersen
Articles
Independent and Cooperative Roles of Adaptor Molecules in Proximal Signaling during FcεRI-Mediated Mast Cell Activation
Taku Kambayashi, Mariko Okumura, Rebecca G. Baker, Chih-Jung Hsu, Tobias Baumgart, Weiguo Zhang, Gary A. Koretzky
Articles | Spotlight
miR-375 Inhibits Differentiation of Neurites by Lowering HuD Levels
Kotb Abdelmohsen, Emmette R. Hutchison, Eun Kyung Lee, Yuki Kuwano, Mihee M. Kim, Kiyoshi Masuda, Subramanya Srikantan, Sarah S. Subaran, Bernard S. Marasa, Mark P. Mattson, Myriam Gorospe
Articles
CTCF Controls Expression and Chromatin Architecture of the Human Major Histocompatibility Complex Class II Locus
Parimal Majumder, Jeremy M. Boss
Articles
Cross Talk between Insulin and Bone Morphogenetic Protein Signaling Systems in Brown Adipogenesis
Hongbin Zhang, Tim J. Schulz, Daniel O. Espinoza, Tian Lian Huang, Brice Emanuelli, Karsten Kristiansen, Yu-Hua Tseng
Articles
Islet β-Cell-Specific MafA Transcription Requires the 5′-Flanking Conserved Region 3 Control Domain
Jeffrey C. Raum, Chad S. Hunter, Isabella Artner, Eva Henderson, Min Guo, Lynda Elghazi, Beatriz Sosa-Pineda, Takeshi Ogihara, Raghavendra G. Mirmira, Lori Sussel, Roland Stein
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Deficiency in a Glutamine-Specific Methyltransferase for Release Factor Causes Mouse Embryonic Lethality
Peng Liu, Song Nie, Bing Li, Zhong-Qiang Yang, Zhi-Mei Xu, Jian Fei, Chyuansheng Lin, Rong Zeng, Guo-Liang Xu
Articles
Genes of the Ecdysone Biosynthesis Pathway Are Regulated by the dATAC Histone Acetyltransferase Complex in Drosophila
T. Pankotai, C. Popescu, D. Martín, B. Grau, N. Zsindely, L. Bodai, L. Tora, A. Ferrús, I. Boros
Articles
The Embryonic Transcription Cofactor LBH Is a Direct Target of the Wnt Signaling Pathway in Epithelial Development and in Aggressive Basal Subtype Breast Cancers
Megan E. Rieger, Andrew H. Sims, Ebony R. Coats, Robert B. Clarke, Karoline J. Briegel
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Protein Tyrosine Kinase 6 Directly Phosphorylates AKT and Promotes AKT Activation in Response to Epidermal Growth Factor
Yu Zheng, Maoyu Peng, Zebin Wang, John M. Asara, Angela L. Tyner
Articles | Spotlight
Dynamic Localization of Fus3 Mitogen-Activated Protein Kinase Is Necessary To Evoke Appropriate Responses and Avoid Cytotoxic Effects
Raymond E. Chen, Jesse C. Patterson, Louise S. Goupil, Jeremy Thorner
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Human Pat1b Connects Deadenylation with mRNA Decapping and Controls the Assembly of Processing Bodies
Sevim Ozgur, Marina Chekulaeva, Georg Stoecklin
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Regulation of the Rho Family Small GTPase Wrch-1/RhoU by C-Terminal Tyrosine Phosphorylation Requires Src
Jamie K. Alan, Anastacia C. Berzat, Brian J. Dewar, Lee M. Graves, Adrienne D. Cox
Articles
The Early Isoform of Disabled-1 Functions Independently of Reelin-Mediated Tyrosine Phosphorylation in Chick Retina
Zhihua Gao, Elizabeth A. Monckton, Darryl D. Glubrecht, Cairine Logan, Roseline Godbout
Articles
Phosphoinositide-Dependent Kinase 1 Provides Negative Feedback Inhibition to Toll-Like Receptor-Mediated NF-κB Activation in Macrophages
Bhagirath Chaurasia, Jan Mauer, Linda Koch, Julia Goldau, Anja-Sterner Kock, Jens C. Brüning