Table of Contents

Articles

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  Articles

  The Unfolded Protein Response Selectively Targets Active Smoothened Mutants

  Suresh Marada, Daniel P. Stewart, William J. Bodeen, Young-Goo Han, Stacey K. Ogden
• Articles

  LOXL4 Is Induced by Transforming Growth Factor β1 through Smad and JunB/Fra2 and Contributes to Vascular Matrix Remodeling

  Oscar Busnadiego, José González-Santamaría, David Lagares, Juan Guinea-Viniegra, Cathy Pichol-Thievend, Laurent Muller, Fernando Rodríguez-Pascual
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  Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels

  Takafumi Suzuki, Tatsuhiro Shibata, Kai Takaya, Kouya Shiraishi, Takashi Kohno, Hideo Kunitoh, Koji Tsuta, Koh Furuta, Koichi Goto, Fumie Hosoda, Hiromi Sakamoto, Hozumi Motohashi, Masayuki Yamamoto
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  Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation

  Jana Bagarova, Ashley J. Vonner, Kelli A. Armstrong, Jan Börgermann, Carol S. C. Lai, Donna Y. Deng, Hideyuki Beppu, Ivan Alfano, Panagis Filippakopoulos, Nicholas W. Morrell, Alex N. Bullock, Petra Knaus, Yuji Mishina, Paul B. Yu
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  Macrophage Glucose-6-Phosphate Dehydrogenase Stimulates Proinflammatory Responses with Oxidative Stress

  Mira Ham, Joo-Won Lee, A Hyun Choi, Hagoon Jang, Goun Choi, Jiyoung Park, Chisayo Kozuka, Dorothy D. Sears, Hiroaki Masuzaki, Jae Bum Kim
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  Arsenic Inhibits Autophagic Flux, Activating the Nrf2-Keap1 Pathway in a p62-Dependent Manner

  Alexandria Lau, Yi Zheng, Shasha Tao, Huihui Wang, Samantha A. Whitman, Eileen White, Donna D. Zhang
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  NuMA Is Required for the Selective Induction of p53 Target Genes

  Hirokazu Ohata, Makoto Miyazaki, Ryo Otomo, Yuko Matsushima-Hibiya, Chihiro Otsubo, Takahiro Nagase, Hirofumi Arakawa, Jun Yokota, Hitoshi Nakagama, Yoichi Taya, Masato Enari
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  Macrophage Fusion Is Controlled by the Cytoplasmic Protein Tyrosine Phosphatase PTP-PEST/PTPN12

  Inmoo Rhee, Dominique Davidson, Cleiton Martins Souza, Jean Vacher, André Veillette
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  Activation of Extracellular Signal-Regulated Kinase but Not of p38 Mitogen-Activated Protein Kinase Pathways in Lymphocytes Requires Allosteric Activation of SOS

  Jesse E. Jun, Ming Yang, Hang Chen, Arup K. Chakraborty, Jeroen P. Roose
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  CAPNS1 Regulates USP1 Stability and Maintenance of Genome Integrity

  Francesca Cataldo, Leticia Y. Peche, Enio Klaric, Claudio Brancolini, Michael P. Myers, Francesca Demarchi, Claudio Schneider
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  BRD4 Coordinates Recruitment of Pause Release Factor P-TEFb and the Pausing Complex NELF/DSIF To Regulate Transcription Elongation of Interferon-Stimulated Genes

  Mira C. Patel, Maxime Debrosse, Matthew Smith, Anup Dey, Walter Huynh, Naoyuki Sarai, Tom D. Heightman, Tomohiko Tamura, Keiko Ozato