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Research Article

Human DnaJB6 Antiamyloid Chaperone Protects Yeast from Polyglutamine Toxicity Separately from Spatial Segregation of Aggregates

Jyotsna Kumar, Neila L. Kline, Daniel C. Masison
Jyotsna Kumar
aLaboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
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Neila L. Kline
aLaboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
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Daniel C. Masison
aLaboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
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DOI: 10.1128/MCB.00437-18
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Article Information

DOI 
https://doi.org/10.1128/MCB.00437-18
PubMed 
30224519

Published By 
American Society for Microbiology Journals
History 
  • Received September 5, 2018
  • Returned for modification September 7, 2018
  • Accepted September 10, 2018
  • Published online November 13, 2018.

Copyright & Usage 
This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply.

Article Versions

  • Accepted Manuscript version (September 17, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Jyotsna Kumara,
  2. Neila L. Klinea and
  3. Daniel C. Masisona
  1. aLaboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
  • Address correspondence to Daniel C. Masison, danielmas{at}niddk.nih.gov.
  • J.K. and N.L.K. contributed equally.

  • Citation Kumar J, Kline NL, Masison DC. 2018. Human DnaJB6 antiamyloid chaperone protects yeast from polyglutamine toxicity separately from spatial segregation of aggregates. Mol Cell Biol 38:e00437-18. https://doi.org/10.1128/MCB.00437-18.

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Human DnaJB6 Antiamyloid Chaperone Protects Yeast from Polyglutamine Toxicity Separately from Spatial Segregation of Aggregates
Jyotsna Kumar, Neila L. Kline, Daniel C. Masison
Molecular and Cellular Biology Nov 2018, 38 (23) e00437-18; DOI: 10.1128/MCB.00437-18

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Human DnaJB6 Antiamyloid Chaperone Protects Yeast from Polyglutamine Toxicity Separately from Spatial Segregation of Aggregates
Jyotsna Kumar, Neila L. Kline, Daniel C. Masison
Molecular and Cellular Biology Nov 2018, 38 (23) e00437-18; DOI: 10.1128/MCB.00437-18
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KEYWORDS

DnaJB6
Huntington's disease
J-protein
molecular chaperone
heat shock protein (HSP)
amyloid

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