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Research Article | Spotlight

Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor

Ji Seul Han, Jung Hyun Lee, Jinuk Kong, Yul Ji, Jiwon Kim, Sung Sik Choe, Jae Bum Kim
Ji Seul Han
aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
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Jung Hyun Lee
aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
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Jinuk Kong
aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
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Yul Ji
aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
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Jiwon Kim
aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
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Sung Sik Choe
aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
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Jae Bum Kim
aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
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DOI: 10.1128/MCB.00390-18
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Article Information

DOI 
https://doi.org/10.1128/MCB.00390-18
PubMed 
30397073

Published By 
American Society for Microbiology Journals
History 
  • Received August 1, 2018
  • Returned for modification August 24, 2018
  • Accepted October 22, 2018
  • Published online January 3, 2019.

Copyright & Usage 
Copyright © 2019 American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (November 05, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Ji Seul Hana,
  2. Jung Hyun Leea,
  3. Jinuk Konga,
  4. Yul Jia,
  5. Jiwon Kima,
  6. Sung Sik Choea and
  7. Jae Bum Kima
  1. aNational Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University, Seoul, South Korea
  • Address correspondence to Jae Bum Kim, jaebkim{at}snu.ac.kr.
  • J.S.H. and J.H.L. contributed equally to this work.

  • Citation Han JS, Lee JH, Kong J, Ji Y, Kim J, Choe SS, Kim JB. 2019. Hypoxia restrains lipid utilization via protein kinase A and adipose triglyceride lipase downregulation through hypoxia-inducible factor. Mol Cell Biol 39:e00390-18. https://doi.org/10.1128/MCB.00390-18.

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Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor
Ji Seul Han, Jung Hyun Lee, Jinuk Kong, Yul Ji, Jiwon Kim, Sung Sik Choe, Jae Bum Kim
Molecular and Cellular Biology Jan 2019, 39 (2) e00390-18; DOI: 10.1128/MCB.00390-18

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Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor
Ji Seul Han, Jung Hyun Lee, Jinuk Kong, Yul Ji, Jiwon Kim, Sung Sik Choe, Jae Bum Kim
Molecular and Cellular Biology Jan 2019, 39 (2) e00390-18; DOI: 10.1128/MCB.00390-18
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KEYWORDS

ATGL
HIF
PKA
hypoxia
lipolysis

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