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Research Article | Spotlight

TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity

Alexandra M. Pike, Margaret A. Strong, John Paul T. Ouyang, Carol W. Greider
Alexandra M. Pike
aDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
bGraduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Margaret A. Strong
aDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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John Paul T. Ouyang
aDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
cGraduate Program in Biochemistry Cell and Molecular Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Carol W. Greider
aDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
bGraduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
cGraduate Program in Biochemistry Cell and Molecular Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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DOI: 10.1128/MCB.00593-18
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Article Information

DOI 
https://doi.org/10.1128/MCB.00593-18
PubMed 
31383750

Published By 
American Society for Microbiology Journals
History 
  • Received December 30, 2018
  • Returned for modification February 10, 2019
  • Accepted July 30, 2019
  • Published online October 11, 2019.

Copyright & Usage 
Copyright © 2019 Pike et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Article Versions

  • Accepted Manuscript version (August 05, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. Alexandra M. Pikea,b*,
  2. Margaret A. Stronga,
  3. John Paul T. Ouyanga,c and
  4. Carol W. Greidera,b,c
  1. aDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  2. bGraduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  3. cGraduate Program in Biochemistry Cell and Molecular Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  • Address correspondence to Carol W. Greider, cgreider{at}jhmi.edu.
  • ↵* Present address: Alexandra M. Pike, MIT Department of Biology, Cambridge, Massachusetts, USA.

  • Citation Pike AM, Strong MA, Ouyang JPT, Greider CW. 2019. TIN2 functions with TPP1/POT1 to stimulate telomerase processivity. Mol Cell Biol 39:e00593-18. https://doi.org/10.1128/MCB.00593-18.

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TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity
Alexandra M. Pike, Margaret A. Strong, John Paul T. Ouyang, Carol W. Greider
Molecular and Cellular Biology Oct 2019, 39 (21) e00593-18; DOI: 10.1128/MCB.00593-18

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TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity
Alexandra M. Pike, Margaret A. Strong, John Paul T. Ouyang, Carol W. Greider
Molecular and Cellular Biology Oct 2019, 39 (21) e00593-18; DOI: 10.1128/MCB.00593-18
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KEYWORDS

POT1
TIN2
TPP1
alternative splicing
processivity
shelterin
telomerase
telomere

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