Cover photograph: ¹⁵N/¹⁴N nanoscale secondary ion mass spectrometry image showing [¹⁵N]anthrolysin O domain 4 (ALO-D4) binding to 3T3-L1 cells treated with an Aster-Aspecific antisense oligonucleotide. [¹⁵N]ALO-D4 binding reflects the accessible pool of plasma membrane cholesterol. (See related article at e00255-20.) (Copyright © 2020 American Society for Microbiology. All Rights Reserved.)