DOI: 10.1128/MCB.00627-20
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- Top
- Article
- ABSTRACT
- INTRODUCTION
- SHOC2 DISCOVERY
- SHOC2: A CANONICAL LRR PROTEIN
- THE MRAS/SHOC2/PP1 HOLOPHOSPHATASE
- THE MRAS/RAF1/SHOC2/HUWE1 COMPLEX
- ERBIN/SCRIB: LAP PROTEINS CONTROL SHOC2-MEDIATED MAPK SIGNALING
- NONCANONICAL ROLE OF RPTOR IN MAPK SIGNALING
- SHOC2 PHOSPHORYLATION AND DEGRADATION CONTROL
- SHOC2 IN PI3K-AKT AND MTOR SIGNALING
- THE DYNAMICS OF SHOC2 SUBCELLULAR LOCALIZATION
- SHOC2 IN RAS MUTANT CANCERS
- SHOC2 AS A POTENTIAL THERAPEUTIC TARGET
- FURTHER AREAS OF INTEREST IN SHOC2 BIOLOGY
- ACKNOWLEDGMENTS
- REFERENCES
- Figures & Data
- Info & Metrics