RT Journal Article
SR Electronic
T1 Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.
JF Molecular and Cellular Biology
JO Mol. Cell. Biol.
FD American Society for Microbiology
SP 851
OP 853
DO 10.1128/MCB.9.2.851
VO 9
IS 2
A1 Fornace, A J
A1 Zmudzka, B
A1 Hollander, M C
A1 Wilson, S H
YR 1989
UL http://mcb.asm.org/content/9/2/851.abstract
AB Only a few of the genes involved in DNA repair in mammalian cells have been isolated, and induction of a DNA repair gene in response to DNA damage has not yet been established. DNA polymerase beta (beta-polymerase) appears to have a synthetic role in DNA repair after certain types of DNA damage. Here we show that the level of beta-polymerase mRNA is increased in CHO cells after treatment with several DNA-damaging agents.