TABLE 1.

Human homologs to yeast NuA4 subunits

Yeast NuA4 subunitHuman homolog(s)Domain(s)a
Tra1TRRAP (transformation/transcription domain-associated protein)PI-3 kinase/ATM
Eaf1hDomino? (p400)SANT, HSA
Epl1Enhancer of Polycomb (EPC1, EPC-like)EpcA
Eaf2DMAP1 (DNMT1-associated protein)SANT
Arp4BAF53a (BRG1-associated factor)Actin related
Esa1Tip60/Tip60b (Tat interactive protein)Chromodomain/MYST HAT
Eaf3Mortality factor related genes (MORF4, MRG15/X)Chromodomains
Act1Actin
Yng2Inhibitor of growth gene family (ING1 to -5)PHD finger
Eaf5?
Yaf9YEATS family (AF9, ENL, GAS41)YEATS
Eaf6hEaf6 (FLJ11730)
  • a PI-3 kinase, phosphatidylinositol 3-kinase.