TABLE 2.

Sequence comparisons between TrexBF candidate binding sites and the MCK Trex site

SequenceBase(s)
CNBP (reverse)aCACCCCAG
Trex permittedC/A/TAC/TC/TC/T/GGAG/A/T
MCK TrexCACCCGAG
MEF3 (reverse)bAACCTGA
Trex permittedC/A/TAC/TC/TC/T/GGAG/A/T
MCK TrexCACCCGAG
  • a Comparison between the CNBP (reverse) consensus sequence, the Trex permitted sequence (based on individual base pair mutation), and the Trex sequence from the MCK enhancer. Matching bases are indicated in bold, and mismatches with the candidate binding site are underlined.

  • b Comparison between the MEF3 (reverse) consensus sequence (the element recognized by Six proteins), the Trex permitted sequence, and the Trex sequence from the MCK enhancer.