TABLE 4.

Effect of rad52 group mutations on the frequency of two BIRa events

Relevant genotypeFrequency of BIR (10−2)Frequency relative to wild type
RAD17 ± 15100
rad52<0.004<0.02
rad51<0.009<0.05
rad597.8 ± 5.246
rad51 rad59<0.008<0.05
rad5013 ± 1176
rad50 rad510.018 ± 0.030.1
rad50 rad595.6 ± 333
rad50 rad51 rad59<0.005<0.03
  • a The frequency of BIR is the number of stable Ura+ transformants per microgram with cut DNA divided by the number of transformants per microgram with uncut DNA transformed and corrected for the number containing CFs.