TABLE 1.

Half-lives of Nrf2 proteins

Nrf2 proteinat1/2 (h)b
Wild-type Nrf21.23
R7-Nrf22.96
  • a MDA-MB-231 cells were transfected with expression vectors for wild-type Keap1 and either wild-type Nrf2 or R7-Nrf2. The ratio of expression vectors for Keap1 and Nrf2 in the transfection was 1:4.

  • b The half-life of HA-Nrf2 was determined by pulse-chase labeling.