TABLE 1.

Body fat content of PI5P4Kβ+/+, PI5P4Kβ+/−, and PI5P4Kβ−/− mice

MethodGenderGenotypeaAge (wk)Diet% Body fatbn
DEXAScan
MaleWT10Chow17.2 ± 1.58
MaleKO10Chow16.0 ± 1.78
MaleWT26Chow31.1 ± 2.68
MaleKO26Chow21.6 ± 4.7**8
FemaleWT30Chow23.9 ± 6.96
FemaleKO30Chow22.0 ± 5.86
Carcass analysis
MaleWT36Chow38.7 ± 2.27
MaleHET36Chow30.5 ± 2.8*6
MaleKO36Chow17.6 ± 2.5**,#6
FemaleWT21Chow18.3 ± 8.810
FemaleKO21Chow17.7 ± 4.210
FemaleWT36High fat47.6 ± 11.010
FemaleHET36High fat38.9 ± 14.814
FemaleKO36High fat41.0 ± 18.911
  • a WT, wild type; KO, knockout; HET, heterozygous.

  • b *, P < 0.05 compared to wild type; **, P < 0.01 compared to wild type; #, P < 0.05 compared to heterozygotes.