TABLE 3.

TUNEL results

GenotypeNo. of TUNEL-positive β-cell nuclei per islet
3 mo9-12 mo
Wild type0.0034 ± 0.00070.0018 ± 0.0012
cyclin D2−/−0.0022 ± 0.00210.0024 ± 0.0024
cyclin D1+/− D2−/−0.0020 ± 0.0020Dead