TABLE 2.

Characteristics of mice by age group

GenotypeResult for mice in indicated age group
Fasting blood glucose (mg/dl)Fed blood glucose (mg/dl)Fasting serum insulin (pg/ml)Fed serum insulin (pg/ml)
3 moP9-12 moP3 moP9-12 moP3 moP9-12 moP3 moP9-12 moP
Wild type89 ± 10136 ± 11139 ± 6155 ± 15371 ± 218        2,068 ± 1,074        1,131 ± 638        4,141 ± 1788
cyclin D2−/−100 ± 10171 ± 19143 ± 7262 ± 27<0.05≤156213 ± 78<0.051,935 ± 638559 ± 152<0.01
cyclin D1+/−71 ± 10N.D.a130 ± 3N.D.≤156N.D.259 ± 167N.D.
cyclin D1+/− D2−/−282 ± 78<0.05Dead454 ± 64<0.01Dead217 ± 141Dead1,183 ± 571Dead
  • a N.D., not done.