Characteristics of mice by age group
| Genotype | Result for mice in indicated age group | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fasting blood glucose (mg/dl) | Fed blood glucose (mg/dl) | Fasting serum insulin (pg/ml) | Fed serum insulin (pg/ml) | |||||||||||||
| 3 mo | P | 9-12 mo | P | 3 mo | P | 9-12 mo | P | 3 mo | P | 9-12 mo | P | 3 mo | P | 9-12 mo | P | |
| Wild type | 89 ± 10 | 136 ± 11 | 139 ± 6 | 155 ± 15 | 371 ± 218 | 2,068 ± 1,074 | 1,131 ± 638 | 4,141 ± 1788 | ||||||||
| cyclin D2−/− | 100 ± 10 | 171 ± 19 | 143 ± 7 | 262 ± 27 | <0.05 | ≤156 | 213 ± 78 | <0.05 | 1,935 ± 638 | 559 ± 152 | <0.01 | |||||
| cyclin D1+/− | 71 ± 10 | N.D.a | 130 ± 3 | N.D. | ≤156 | N.D. | 259 ± 167 | N.D. | ||||||||
| cyclin D1+/− D2−/− | 282 ± 78 | <0.05 | Dead | 454 ± 64 | <0.01 | Dead | 217 ± 141 | Dead | 1,183 ± 571 | Dead | ||||||
↵a N.D., not done.