TABLE 3.

Enrichment of transcription factor motifs (TFMs) and MIPS functional categories in clusters of genes that were differentially expressed in response to anaerobiosis in glucose medium (wild-type strain, SOM clustering with 1D ring topology)a

Cluster no.nTFMReference(s)Percentage sharePMIPS functional categoryP (genomic)
In setGenomic
120MSN2/446955.38.0Metabolism of energy reserves (glycogen, trehalose)11.0
MIG146503.74.5C-compound and carbohydrate metabolism5.7
216MSN2/446883.15.0Cell rescue, defense, and virulence4.4
316ABF191632.02.1Respiration/mitochondrion/energy≥3.5
Transport ATPases3.8
434HAP2/3/4/546443.04.8Respiration/mitochondrion/energy≥8.7
HAP148262.34.9
540PDR154132.43.9Respiration/mitochondrion≥2.7
Homeostasis of cations2.2
675Mitochondrion14.0
Ribosome biogenesis8.5
Phosphate metabolism2.2
710ACE254, 91703.03.2C-compound and carbohydrate metabolism3.6
NDD154502.83.4
SWI454502.63.0
842ROX117952.74.0Vitamin, cofactor, and prosthetic group biosynthesis2.1
HAP2/3/4/554622.62.8
934UPC216767.912.7ABC transporters3.4
Cell rescue, defense, and virulence3.2
1038MCM146, 76, 91823.65.2Cell wall5.6
GLN391712.12.3Cell rescue, defense, and virulence3.7
UPC216634.89.0C-compound and carbohydrate utilization2.4
1120
07Mitochondrion2.2
  • a See Table 1, footnotes a to d.