TABLE 3.

Frequency of NK cells in spleens of ISG15-deficient micea

Duration of poly(I:C) treatment and dosePhenotype% of total cells in spleen
ISG15+/+ISG15−/−
36 h
    0 μgCD3 DX5+ 8.4 ± 0.38.1 ± 0.7
    500 μgCD3 DX5+ 13.2 ± 1.212.6 ± 0.7
3 days
    500 μg/dayCD3 DX5+ 20.3 ± 1.321.1 ± 0.9
  • a Mean percentage ± standard error of the mean is given for groups of 5 to 12 animals analyzed.