TABLE 1.

Average recombination rate and standard error in the hprt gene and SCneo constructs as determined by fluctuation assays in S8SN.11 cells

TreatmentRecombination rateExpected recombination rate, SCneo and hprtObserved recombination rate, SCneo and hprt
hprtSCneo
None5.5 ± 0.3 × 10−62.5 ± 0.8 × 10−61.4 × 10−11< 9.8 × 10−11
Thymidine (10 mM)1.6 ± 0.4 × 10−57.2 ± 2.5 × 10−61.1 × 10−10< 9.6 × 10−11