TABLE 2.

Multiply used rearrangement breakpoints are observed more frequently than expected

Breakpoint usageaNo. of source breakpointsb (avg identity length)No. of target breakpointsb (avg identity length)
Last IDcFirst IDcRandomdLast IDcFirst IDcRandomd
1286 (3.3)299 (3.3)348281 (3.7)282 (3.7)334
231 (3.7)25 (3.4)1024 (4.5)23 (4.7)0
32 (2.2)3 (6.0)03 (4.9)2 (8.5)0
41 (8.25)00000
  • a Number of times that any single nucleotide was at a rearrangement.

  • b Number of nucleotide positions that are rearrangements.

  • c Distributions calculated using the first and last identifiable definitions for breakpoints (see Fig. 2A).

  • d Number of identical breakpoints that would be predicted by a Poisson distribution of 358 events in 12 kb (for the chromosome V source) or 334 events in 12 Mb (for the unique genome targets).