TABLE 1.

Blood analysisa

Mice and treatmentWBCs (103/μl)RBCs (103/μl)Hb (g/dl)PLT (103/μl)% in blood WBCs
LymphocytesNeutrophilsEosinophilsMonocytes
Before poly(I · C)
    WT (n = 4)9.5 ± 2.99.8 ± 0.312.6 ± 2.4995 ± 11981.1 ± 2.613.5 ± 2.51.9 ± 1.83.5 ± 0.6
    Ube1L−/− (n = 4)9.5 ± 1.38.9 ± 1.313.2 ± 2.3930 ± 10280.9 ± 1.912.8 ± 3.42.9 ± 1.33.6 ± 1.4
After poly (I · C)
    WT (n = 4)7.3 ± 1.48.2 ± 1.512.6 ± 3.4954 ± 22467.4 ± 2.926.1 ± 4.32.9 ± 1.73.6 ± 1.4
    Ube1L−/− (n = 4)9.5 ± 1.38.5 ± 1.012.5 ± 1.5928 ± 5067.0 ± 2.426.6 ± 3.82.6 ± 1.33.6 ± 0.8
  • a Samples were collected via retro-orbital bleeding from wild-type (WT) and Ube1L knockout (Ube1L−/−) mice before and after daily poly(I·C) injections for 2 days. WBCs, white blood cells; RBCs, red blood cells; Hb, hemoglobin; PLT, platelets. Values are means ± standard deviations.