TABLE 1.

Phenotypes of leukemias induced by coexpressed Hoxa7 and Meis1c

Cell type injectedLatency (days)Organ wt (mg)WBC count (1,000/μl)bLeukemia FACSa
SpleenNodeMacI+B220+
Hoxa7 + Meis1 (progenitor line)70 ± 10500 ± 10026 ± 585 ± 1778 ± 1625 ± 6
Hoxa7 + Meis1 (fresh marrow)74 ± 21637 ± 20031 ± 692 ± 1280 ± 1818 ± 9
  • a FACS results (percentage) of leukemia cells from spleen and bone marrow.

  • b WBC, white blood cells in peripheral blood.

  • c Values are averages ± standard deviations.