TABLE 2.

Phenotypic abnormalities in ATX-deficient embryos and yolk sacsa

Stage and phenotype% PenetranceNo. of embryos analyzed
E8.5
    Allantois malformation4129
    Neural tube malformation7512
    Dorsal effusions4427
    Asymmetric headfolds8335
E9.5
    No yolk sac vascularization10026
    Enlarged vessels in embryo1004
    No axial turning8526
    Dorsal effusions4226
    Enlarged head region5426
  • a See text for further details.