TABLE 3.

Expression of the 1.36kb γpr-β gene in 1.36kb γpr-βYAC transgenic micea

LineCopy no.Gene expressionb (mean ± SD) in:
Day 12 bloodDay 12 YSDay 12 FLDay 14 bloodDay 14 FLDay 16 bloodDay 16 FLAd blood
A41.4 ± 1.01.8 ± 0.719.1 ± 4.79.9 ± 4.212.8 ± 1.811.7 ± 2.610.2 ± 2.30.5 ± 0.1
B22.4 ± 0.22.4 ± 0.521.7 ± 6.917.1 ± 2.412.5 ± 1.110.2 ± 0.09.0 ± 0.02.2 ± 0.4
C20.8 ± 0.10.8 ± 0.17.6 ± 2.25.7 ± 0.49.6 ± 1.48.3 ± 1.57.1 ± 2.32.5 ± 0.4
Avg1.5 ± 0.81.7 ± 0.816.1 ± 7.510.9 ± 5.811.7 ± 1.810.1 ± 1.78.8 ± 1.51.7 ± 1.1
Αmt of β gene expression in wt YAC2.9 ± 1.25.1 ± 2.043.9 ± 15.749.2 ± 3.643.4 ± 2.156.1 ± 2.849.6 ± 4.7126.9 ± 23.0
  • a YS, yolk sac; FL, fetal liver; wt, wild type; Ad, adult.

  • b Percentage of α-like globin genes per copy.