TABLE 5.

Expression of 1.36kb γpr-β gene in (1.36kb γpr-β)(ΔGγAγ) YAC transgenic micea

LineCopy no.Gene expressionb (mean ± SD) in:
Day 12 bloodDay 12 YSDay 12 FLDay 14 bloodDay 14 FLDay 16 bloodDay 16 FLAd blood
A220.8 ± 2.729.1 ± 5.239.3 ± 0.233.2 ± 2.721.7 ± 8.324.7 ± 3.924.2 ± 4.34.3 ± 0.5
B116.4 ± 2.929.2 ± 9.312.6 ± 8.112.6 ± 1.89.5 ± 5.01.2 ± 0.9
C223.4 ± 1.735.4 ± 2.620.6 ± 3.314.4 ± 0.912.4 ± 4.48.9 ± 0.812.7 ± 0.80.9 ± 0.0
D133.3 ± 3.737.6 ± 8.255.5 ± 26.932.2 ± 6.223.5 ± 8.132.126.62.7 ± 0.8
E228.4 ± 3.452.4 ± 13.855.2 ± 0.835.6 ± 4.537.9 ± 12.237.1 ± 2.88.9 ± 1.1
Avg24.5 ± 6.636.8 ± 9.536.7 ± 19.725.6 ± 11.221.0 ± 11.225.7 ± 12.321.2 ± 7.43.6 ± 3.3
Αmt of γ gene expression in wt YAC29.4 ± 2.035.8 ± 10.313.2 ± 2.95.6 ± 1.32.8 ± 0.41.9 ± 0.51.2 ± 0.3<0.1
  • a YS, yolk sac; FL, fetal liver; wt, wild type; Ad, adult.

  • b Percentage of murine α-like globin genes per copy.