Table 6.

Absence of Cds1 exacerbates deletion mutator phenotype

AlleleTemp (°C)Relative mutation rate in cellsa
cds1+cds1Δ
Wild-type301.0≤1.0
polαts11 2150.7SL
polαts13 2152.4
polδts1 211.324.3
polδts2 25≤1.0≤1.0
polδts3 252.412.2
cdc6-121 254.416.0
cdc1-7 212.018.6
cdc27-K3 25≤1.05.9
cdc17-K42 252.08.1
rad2Δ3016.511.4
  • a The relative mutation rate is the rate compared to that of wild-type cells. SL, synthetic lethal; −, grew too poorly to be assayed.